Results 181 to 190 of about 6,030,936 (310)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Exploring Environmental Element Monitoring Data Using Chemometric Techniques: A Practical Case Study from the Tremiti Islands (Italy). [PDF]

Molecules
Russo RE, Fattobene M, Zamponi S, Conti P, Herrero A, Berrettoni M.   +5 more
europepmc   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Data Flow Quality Monitoring in Data Infrastructures

, 2017
In the last decade, a lot of attention worldwide has been brought by researchers, organizations, and funders on the realization ofData Infrastructures (DIs), namely systems supporting researchers with the broad spectrum of resources they need to perform science. DIs are here intended as ICT (eco)systems offering data and processing components which can
openaire   +2 more sources

Beyond Time in Range: Hidden Statistical Challenges of Continuous Glucose Monitoring Data in Diabetes Drug Development. [PDF]

J Diabetes Sci Technol
Kim Y, Crackel R, Cho HS, Tu W, Wang Y.
europepmc   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Monitoring data of the openLAB research bridge - Part 1: Reference condition. [PDF]

Data Brief
Jansen A, Herbers M, Richter B, Walker M, Jesse F, Marx S.   +5 more
europepmc   +1 more source

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

FEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca, Anna Tricarico, Martina Furfaro, Priyam Ghosh, Ennio Prosperi, Lucia Anna Stivala, Ornella Cazzalini   +6 more
wiley   +1 more source

Real-time traffic monitoring using mobile phone data [PDF]

, 2005
Wilson, Eddie
core  

Implantable Cardioverter-Defibrillator Therapies Following Generator Replacements-Long-Term Remote Monitoring Data. [PDF]

Clin Pract
Dyrbuś M, Pyka Ł, Kurek A, Niedziela J, Adamowicz-Czoch E, Sokoła K, Machowicz J, Ostręga M, Pres D, Skrzypek M, Gąsior M, Tajstra M.   +11 more
europepmc   +1 more source