Results 161 to 170 of about 2,173,093 (267)

Estimating PM₂.₅-influenza risk using home-school-commute exposure modeling from hourly monitoring data: schoolchildren in Guangzhou, China, 2014-2019. [PDF]

BMC Public Health
Jing F, Hu J, Zhou S, Kan Z, He G, Hu J, Liu T, Zhang M, Luo L, Ma M, Lin Z, Zhu S, Liu Y, Ma W.   +13 more
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Bidirectional associations between sleep and physical activity investigated using large-scale objective monitoring data. [PDF]

Commun Med (Lond)
Fitton J, Nguyen DP, Lechat B, Scott H, Toson B, Manners J, Dunbar C, Sansom K, Pinilla L, Hudson A, Naik G, Vakulin A, Reynolds AC, Catcheside P, Escourrou P, Eckert DJ.   +15 more
europepmc   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Identification of Statewide Hotspots for Respiratory Disease Targets Using Wastewater Monitoring Data. [PDF]

Trop Med Infect Dis
Servello D, Chalasani P, Leasure E, LeMaster KD, Kellar J, Stiverson J, White M, Bohrerova Z.   +7 more
europepmc   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

FEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Monitoring data of the openLAB research bridge - Part 1: Reference condition. [PDF]

Data Brief
Jansen A, Herbers M, Richter B, Walker M, Jesse F, Marx S.   +5 more
europepmc   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Beyond Time in Range: Hidden Statistical Challenges of Continuous Glucose Monitoring Data in Diabetes Drug Development. [PDF]

J Diabetes Sci Technol
Kim Y, Crackel R, Cho HS, Tu W, Wang Y.
europepmc   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source