Results 141 to 150 of about 2,173,093 (267)

A novelty mode decomposition method and its application in dynamic characteristic identification of bridge GNSS monitoring data. [PDF]

Sci Prog
Wang X, Luo L, Liu J.
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Atmospheric mercury monitoring data across Italy: A multi-year national dataset (2020 - 2023). [PDF]

Data Brief
Bencardino M, Tassone A, Martino M, D'Amore F, Sprovieri T, Ungaro C, Andreoli V, Esposito G, Siliprandi G, Lanzani G, Angiuli L, Nocioni A, Leonardi C, Sprovieri F, Pirrone N.   +14 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Twenty years (2000-2020) of butterfly monitoring data across the contiguous United States. [PDF]

Sci Data
Henry EH, Edwards CB, Shirey V, Pippen JS, Waetjen D, Forister ML, Larsen EA, Schultz CB, Michielini J, Brockman N, Burls KJ, Drum RG, Gatch M, Glassberg J, Hamlett NV, Hershcovich S, Le C, McGaffin S, Meilinger J, Richter L, Rochefort R, Schelz C, Shapiro AM, Sullivan K, Taron DJ, Thogmartin WE, Walker A, Westphal A, Wiedmann J, Wilcockson IU, Zaspel J, Ries L.   +31 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Natural Language Processing for Automated Extraction of Continuous Glucose Monitoring Data. [PDF]

Diabetes Care
Zheng Y, Song Y, Iturrate E, Wu B, Zweig S, Johnson SB.   +5 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Long-term biodiversity monitoring data from two hydroelectric dam projects in northeast Portugal, 2006-2023. [PDF]

Sci Data
Múrias T, Figueira R, Madeira J, Bertoluci V, Beja P.   +4 more
europepmc   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source