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Non-viral generation of marmoset monkey iPS cells by a six-factor-in-one-vector approach. [PDF]

open access: yesPLoS ONE, 2015
Groundbreaking studies showed that differentiated somatic cells of mouse and human origin could be reverted to a stable pluripotent state by the ectopic expression of only four proteins.
Katharina Debowski   +8 more
doaj   +2 more sources

Comparative plasma lipidome between human and cynomolgus monkey: are plasma polar lipids good biomarkers for diabetic monkeys? [PDF]

open access: yesPLoS ONE, 2011
BACKGROUND: Non-human primates (NHP) are now being considered as models for investigating human metabolic diseases including diabetes. Analyses of cholesterol and triglycerides in plasma derived from NHPs can easily be achieved using methods employed in ...
Guanghou Shui   +7 more
doaj   +2 more sources

Establishment of porcine and monkey colonic organoids for drug toxicity study

open access: yesCell Regeneration, 2021
Pig and monkey are widely used models for exploration of human diseases and evaluation of drug efficiency and toxicity, but high cost limits their uses.
Haonan Li   +7 more
doaj   +1 more source

A draft map of rhesus monkey tissue proteome for biomedical research. [PDF]

open access: yesPLoS ONE, 2015
Though the rhesus monkey is one of the most valuable non-human primate animal models for various human diseases because of its manageable size and genetic and proteomic similarities with humans, proteomic research using rhesus monkeys still remains ...
Jin-Gyun Lee   +9 more
doaj   +1 more source

Sequence Analysis of Macaca mulatta TRIM4 and Its Role in the Interferon Pathway

open access: yesFrontiers in Veterinary Science, 2022
Monkey diseases are becoming increasingly severe, and some may be transmitted to humans through direct and indirect contact. Innate immunity is the first line of defense against foreign microorganisms.
Mengmeng Zhao   +5 more
doaj   +1 more source

Single-Cell Analysis Identify Transcription Factor BACH1 as a Master Regulator Gene in Vascular Cells During Aging

open access: yesFrontiers in Cell and Developmental Biology, 2021
Vascular aging is a potent driver of cardiovascular and cerebrovascular diseases. Vascular aging features cellular and functional changes, while its molecular mechanisms and the cell heterogeneity are poorly understood.
Fei Ge   +12 more
doaj   +1 more source

Heterogeneity of circulating CD4+CD8+ double-positive T cells characterized by scRNA-seq analysis and trajectory inference

open access: yesScientific Reports, 2022
The frequency of CD4+CD8+ double-positive (DP) T cells is highly associated with a variety of diseases. Recently, we used high-throughput single-cell RNA sequencing to show that circulating DP T cells in cynomolgus monkeys comprise nine heterogeneous ...
Sung Min Choi   +4 more
doaj   +1 more source

The basic reproductive ratio of the 2022 outbreak of the monkey pox virus disease for the United Kingdom, Canada, Brazil, the United Arab Emirates, and Nigeria

open access: yesBeni-Suef University Journal of Basic and Applied Sciences, 2022
Background A recent outbreak of the monkey pox virus disease (MPVD) started to spread over the world before the second half of the 2022 year. This outbreak of the monkey pox virus disease is known as the 2022 outbreak of the monkey pox virus disease. The
Marwan Al-Raeei
doaj   +1 more source

Brain Region- and Age-Dependent 5-Hydroxymethylcytosine Activity in the Non-Human Primate

open access: yesFrontiers in Aging Neuroscience, 2022
Because of the difficulty in collecting fresh brains of humans at different ages, it remains unknown how epigenetic regulation occurs in the primate brains during aging.
Yanru Xu   +12 more
doaj   +1 more source

CT anatomy and normal radiography of the skull of the Rhesus monkey (Macaca mulatta)

open access: yesVeterinary Medicine and Science, 2023
Background Considering the relationship between human morphology and physiology with the Rhesus monkey, this animal is the most prominent species of laboratory primate for human and animal health research.
Ali Reza Vajhi   +5 more
doaj   +1 more source

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