Results 91 to 100 of about 67,779 (299)

Bearded capuchin monkeys as a model for Alzheimer’s disease

Scientific Reports
Abstract The absence of a natural animal model is one of the main challenges in Alzheimer’s disease research. Despite the challenges of using nonhuman primates in studies, these animals can bridge mouse models and humans, as nonhuman primates are phylogenetically closer to humans and can spontaneously develop AD-type pathology.
Diehl Rodriguez, Roberta, Tavares, Maria, Brucki, Sonia, Takada, Leonel, Otaduy, Maria, da Graça Morais Martin, Maria, Kimie Suemoto, Claudia, Grinberg, Lea, Leite, Claudia, Tomaz, Carlos, Nitrini, Ricardo   +10 more
openaire   +5 more sources

Psychiatric and Cognitive Features in Italian Women With the FMR1 Premutation: A Comprehensive Assessment Using SCID‐5 and Standardized Cognitive Measures

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Women with the FMR1 premutation (PM) are at increased risk for fragile X‐associated conditions (FXPAC), including cognitive and psychiatric features collectively termed fragile X‐associated neuropsychiatric disorders (FXAND). This study is the first to systematically investigate cognitive and psychiatric features in Italian female premutation ...
Federica Alice Maria Montanaro, Randi J. Hagerman, Giuseppina Spano, Flora Tassone, Giancarlo Logroscino, Andrea Bosco   +5 more
wiley   +1 more source

Strategies for inducing diabetes in laboratory animals: Advances from chemical, surgical, immunologic, dietary, and genetic approaches

Animal Models and Experimental Medicine, EarlyView.
This review summarizes the principal experimental approaches used to induce diabetes in animal models. Strategies include chemical agents (streptozotocin, alloxan, dithizone, gold thioglucose), dietary interventions (high‐fat and high‐sugar diets), surgical methods (total or partial pancreatectomy), genetic models (db/db, ob/ob, Goto‐Kakizaki [GK ...
Milad Faraji, Maedeh Faraji, Nasrin Kazemipour   +2 more
wiley   +1 more source

The mechanism of labor in nonhuman primates: A look inside

The Anatomical Record, EarlyView.
Abstract While in humans, the flexed position of the fetus and its rotating course down the birth canal are well documented, in other primates the mechanism of labor is unknown. Despite the lack of comparative data, it is commonly assumed that the human obstetric mechanism is unique, and anthropologists have disputed when and why the transition to the ...
Melissa K. Stoller
wiley   +1 more source

IL‐31 levels correlate with pruritus in patients with cholestatic and metabolic liver diseases and is farnesoid X receptor responsive in NASH

Hepatology, EarlyView., 2022
IL‐31 levels correlate with pruritus in patients with cholestatic and metabolic liver diseases Abstract Background and Aims Pruritus is associated with multiple liver diseases, particularly those with cholestasis, but the mechanism remains incompletely understood.
Jun Xu, Ya Wang, Mina Khoshdeli, Matt Peach, Jen‐Chieh Chuang, Julie Lin, Wen‐Wei Tsai, Sangeetha Mahadevan, Wesley Minto, Lauri Diehl, Ruchi Gupta, Michael Trauner, Keyur Patel, Mazen Noureddin, Kris V. Kowdley, Aliya Gulamhusein, Christopher L. Bowlus, Ryan S. Huss, Robert P. Myers, Chuhan Chung, Andrew N. Billin   +20 more
wiley   +1 more source

Monkeys excluding apes as a model for studies on metabolic syndrome

Бюллетень сибирской медицины
Aim. To summarize the results of research on metabolic syndrome in monkeys excluding apes and to conduct a comparison with humans.A search for full-text publications in PubMed and Scopus databases was carried out using the following keywords: nonhuman ...
S. V. Orlov, Yu. P. Uspensky, Yu. A. Fominykh, Yu. A. Kolesnik, A. V. Panchenko   +4 more
doaj   +1 more source

Role of the Squirrel Monkey in Parasitic Disease Research [PDF]

ILAR Journal, 2000
Much controversy exists regarding the species of the squirrel monkey. Napier and Napier (Whitney 1995) divide the squirrel monkeys into two species: Saimiri sciureus and Saimiri osterdii; the former is used in biomedical research. Hershkovitz prefers to use two groups of Saimiri based on facial characteristics and other factors, which include "Roman ...
openaire   +2 more sources

Human evolution and the obstetrical dilemma: The pelvic floor hypothesis

The Anatomical Record, EarlyView.
Abstract Human childbirth is mechanically difficult because a large‐headed, broad‐shouldered fetus must pass through a comparatively narrow, twisted bony birth canal. Traditional explanations of this “obstetrical dilemma” emphasize the role of bipedal locomotion in inhibiting the evolution of a wider, more spacious pelvis.
Barbara Fischer, Ekaterina Stansfield
wiley   +1 more source

Statistical analysis of "Plasmodium falciparum" infection dynamics [PDF]

, 2012
Malaria is one of the major contributors to the global burden of disease. Worldwide, there were an estimated number of 200 million malaria cases in the year 2008, with a vast majority (85%) of those being in the African Region.
Bretscher, Michael
core   +1 more source

An overview of monkey pox disease as an important disease in the world [PDF]

Archives of Razi Institute
Monkey pox is a viral disease that has received much attention today due to the spread of re-emerging and emerging diseases, especially epidemic diseases.
Sina Soleimani, Najmeh Motamed
doaj   +1 more source