Results 191 to 200 of about 2,336,793 (302)

Multifocal Oral Epithelial Hyperplasia Associated With Papillomavirus Infection in a Road Killed Brown Howler Monkey (Alouatta guariba clamitans). [PDF]

J Med Primatol
Pulecio-Santos SL, Kida VR, de Souza AJS, Catão-Dias JL, Suarez PEN, de Sá LRM.   +5 more
europepmc   +1 more source

Boronic Acid Inhibitors of β‐Lactamases: A Promising Strategy Against Antimicrobial Resistance

Medicinal Research Reviews, EarlyView.
ABSTRACT The rise of antimicrobial resistance (AMR) poses a critical threat to global health, mostly due to the proliferation of β‐lactamases, a class of enzymes responsible for the inactivation of β‐lactam antibiotics. Among the most promising strategies to restore β‐lactam efficacy is the use of β‐lactamase inhibitors (BLIs), with boronic acid ...
Nicolò Santi, Federico Corsini, Robert A. Bonomo, Emilia Caselli, Fabio Prati   +4 more
wiley   +1 more source

Developing the Dopamine D3 Receptor (D3R) Antagonist, (R)‐VK4‐116, as a Non‐Opioid Medication for the Treatment of Opioid Use Disorder

Medicinal Research Reviews, EarlyView.
ABSTRACT Opioid use disorder (OUD) remains a major global health challenge, and currently approved treatments (methadone, buprenorphine, and naltrexone) are all opioid receptor‐targeting drugs with limitations in access, adherence, stigma, and use in polysubstance use disorders. Because the dopamine D3 receptor (D3R) is enriched in limbic brain regions
Chia‐Kuei Wu, Yu‐Chih Lin, Junfeng Huang, Bangwei Ding, Pramod Terse, Rahul Nandre, Haksong Jin, Molly Congdon, Kun Shen, Philip Sanderson, Gregory Tawa, Stephanie Mounaud, Marta De Santis, Donald Lo, Elizabeth A. Ottinger, Amy Hauck Newman   +15 more
wiley   +1 more source

Longitudinal Characterization of Giant <i>ANK2</i>-Depleted Monkeys Suggests Neurodevelopmental-Disorder-Like Phenotypes. [PDF]

Research (Wash D C)
Huang HD, Ji YC, Zhang L, Xu M, Qiao Y, Li CY, Xie HH, Li Y, Zhang BL, Qiu MH, Zhang YL, Yu XM, Zhang YB, Wang Y, Wang Q, Li YJ, Lv LB, Huang XX, Mao BY, Wu DD, Zheng P, Liu N, Wang JH, Yao YG.   +23 more
europepmc   +1 more source

Neurological Adverse Effects Associated With Commonly Used H1‐Antihistamines: A Narrative Review of Age‐Stratified Risk Profiles in Paediatric and Geriatric Populations

Medicine Advances, EarlyView.
This narrative review examines the neurological adverse effects associated with commonly used H1‐antihistamines, focusing on how blood–brain barrier (BBB) penetration and patient age influence central nervous system (CNS) toxicity. The major finding is that first‐generation antihistamines, because of higher CNS penetration, are associated with ...
Syeda Samia Fatima, Zahabia Adnan, Rabia Nizam, Marium Fawad, Zainab Mehmood, Areeba Asif, Ali Aamir   +6 more
wiley   +1 more source

Case Report: Transitional meningioma in a free ranging mantled howler monkey (<i>Alouatta palliata</i>). [PDF]

Front Vet Sci
Romero-Vega M, Gregor K, Hagnauer I, Alfaro-Alarcón A, Beineke A.   +4 more
europepmc   +1 more source

In Vivo Dynamic D2O‐MRI for Quantifying Apparent CSF Water Renewal Across Ventricular and Extraventricular Compartments

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose The choroid plexus has long been regarded as the principal source of cerebrospinal fluid (CSF), yet this view remains unresolved. We developed a dynamic indirect D2O MRI approach to quantify regional apparent CSF water renewal in vivo in rats at 9.4 T.
Zhao Zhang, Yun Wu, Yanmin Zheng, Zhuoyang Lin, Ye Li, Qiong Ye   +5 more
wiley   +1 more source

Molecular Identification of Entamoeba spp. From Captive Proboscis Monkey (Nasalis larvatus) in Indonesia. [PDF]

J Med Primatol
Priastomo IB, Nurhidayah N, Kurniawati DA, Pramardika DD, Ekawasti F, Mufasirin M, Rachmawati K, Hidayatik N.   +7 more
europepmc   +1 more source

Early Identification of Aggression Risk in Hospitalized Adults: Evaluating the Dynamic Appraisal of Situational Aggression Tool

Research in Nursing &Health, EarlyView.
ABSTRACT As violence toward healthcare personnel escalates worldwide, nurses seek methods to identify patients at risk for aggression before harm occurs. Multiple assessment guides for aggression risk are available for psychiatric patients. However, few assessment tools have been tested with patients hospitalized in non‐psychiatric settings.
K. Renee Samples Twibell, Karrie Osborne, Melissa Hicks, Jessica Marshall, Gena Coers, Monica Goble, Guadalupe E. Montero, Sarah Rogillio, James A. Jones   +8 more
wiley   +1 more source

Parasitological study of animals maintained under human care at a Zoobotanical Park in Bahia, Northeastern Brazil. [PDF]

Front Parasitol
Batista AIV, Gurgel JVO, Pereira LMF, Ferreira PRB, Gomes MC, Brasil AWL, Lima VFS, Coelho WAC, Carvalho LRRA, Pereira JS.   +9 more
europepmc   +1 more source