Results 191 to 200 of about 150,516 (303)

Brain Imaging Changes Following Deep Brain Stimulation Patients with Parkinson's Disease: A Literature Review

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Parkinson's Disease (PD) is a progressive neurodegenerative disorder primarily characterized by motor symptoms such as tremors, rigidity, and bradykinesia. Structural brain changes, including atrophy in the midbrain, basal ganglia, and cortical regions such as the frontal and temporal lobes, are observed in advanced stages.
Suraiya Mangra, Stanislaw Szlufik, Chao‐Kai Hu, Alexandre Boutet, Jürgen Germann, Andres M. Lozano   +5 more
wiley   +1 more source

Safety and neuroprotective efficacy of the VCP inhibitor ML240 in large-animal and human retinal explants: a preclinical ex vivo study. [PDF]

BMC Med
Almansa-García AC, Armento A, Cao B, Petremann-Dumé AS, Salmaso S, Caliceti P, Henes C, Bolz S, Kilger E, Süsskind D, Ueffing M, Arango-Gonzalez B.   +11 more
europepmc   +1 more source

What does monkey malaria mean to you? A participatory photovoice study in rural Malaysian Borneo. [PDF]

Malar J
Naserrudin NA, Rahman AB, Manah AM, Donnie EM, Jamaji L, Lin PYP, Miller A, Krishnan M, Hassan MR.   +8 more
europepmc   +1 more source

Convergence Deficits in Myoclonus‐Dystonia Point to Cerebellar Impairment

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Myoclonus‐dystonia (M‐D) is a monogenic movement disorder, with proposed cerebellar dysfunction. Vergence eye movement deficits, characteristics of degenerative cerebellar disease, have not been studied in M‐D. Cerebellar transcranial alternating current stimulation (tACS) is considered a potential therapeutic approach.
Skadi Gerkensmeier, Christina Bolte, Jan‐Ole Radecke, Feline Hamami, Andreas Sprenger, Christoph Helmchen, Robert Chen, Marcus Callister, Talyta Cortez Grippe, Christine Klein, Norbert Brüggemann, Tobias Bäumer, Alexander Münchau, Anne Weissbach   +13 more
wiley   +1 more source

Expert opinion: Seeking truth through inquiry: A discussion on the online news from Science on November 21, "Exclusive: CDC to end all monkey research". [PDF]

Animal Model Exp Med
Xiang Z, Qin C.
europepmc   +1 more source

Quantitative Analysis of Locus Coeruleus Neurons and Thalamic Noradrenergic Axons in a Progressive 1‐Methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine Monkey Model of Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Parkinson's disease is mainly characterized by dopaminergic neurodegeneration in the substantia nigra pars compacta (SNc) and α‐synuclein accumulation. The locus coeruleus (LC) is also affected in Parkinson's disease and linked to some nonmotor symptoms, but the extent and timing of its degeneration remain unclear.
Megan Carrillo, Nagore Hernández‐Pinedo, Josefa Zaldivar‐Diez, Isabel Pérez‐Santos, José A. Obeso, Carmen Cavada, Javier Blesa   +6 more
wiley   +1 more source

When yellow fever silenced the forest: Ecological collapse and reduced malaria transmission in the Rio de Janeiro Atlantic Forest, Brazil. [PDF]

One Health
de Pina-Costa A, Lourenço-de-Oliveira R, Brasil P, Daniel-Ribeiro CT.   +3 more
europepmc   +1 more source

Current Status of Kidney Xenotransplantation in Basic Research

Organ Medicine, EarlyView.
Kidney xenotransplantation is a potential solution to the organ shortage for end‐stage kidney disease. This review systematically elaborates on the application advances of donor pig gene editing technologies, the molecular mechanisms and regulatory strategies of xenogeneic immune rejection, and the optimization approaches of immune compatibility ...
Yu Luo, Bingzhuo Liu, Weijie Lai
wiley   +1 more source

Molecular Characterization of Complete Simian Foamy Virus Genomes from Three Colobine Monkeys Reveals Highly Divergent Evolutionary Trajectories and Identifies Transmission to Humans. [PDF]

Viruses
Shankar A, Zheng H, Cowan D, Jia H, Osis G, Burgin A, Sheth M, Hoff NA, Halbrook M, Rimoin AW, Goldberg TL, Chapman CA, Ting N, Switzer WM.   +13 more
europepmc   +1 more source

Understanding smallholder decision‐making to increase farm tree diversity: Enablers and barriers for forest landscape restoration in Western Kenya

People and Nature, EarlyView.
Abstract Integrating diverse trees and shrubs (hereafter ‘trees’) in agricultural landscapes has emerged as a crucial nature‐based solution to the triple challenge of biodiversity loss, climate change and food security. The potential benefits of on‐farm trees for both people and nature, however, are often constrained by inadequate consideration of ...
Ennia Bosshard, Harrison Carter, Lillian Aluso, Reuben Chumba, Christopher N. Kaiser‐Bunbury, Chris J. Kettle, Ana Nuno   +6 more
wiley   +1 more source