Results 201 to 210 of about 67,779 (299)

Inferring Patterns of Purifying, Positive, and Balancing Selection in the Coppery Titi Monkey (Plecturocebus cupreus) Utilizing a Well-Fit Evolutionary Baseline Model. [PDF]

Genome Biol Evol
Soni V, Versoza CJ, Terbot JW, Spatola GJ, Bales KL, Pfeifer SP, Jensen JD.   +6 more
europepmc   +1 more source

In Utero HSC Transplantation for Sickle Cell Disease: A Potential Therapeutic Approach That Overcomes Complications of Current Therapies

Prenatal Diagnosis, EarlyView.
ABSTRACT Sickle cell disease (SCD) affects millions worldwide but has limited treatment options, most of which carry significant side effects. At present, the only curative treatment for SCD is allogeneic or gene‐modified autologous hematopoietic stem cell (HSC) transplantation (Tx).
Oluwaseun O. Babatunde, Madeleine G. Bibby, Anthony Atala, Graça Almeida‐Porada, Christopher D. Porada   +4 more
wiley   +1 more source

Hepatitis B Virus in Gabonese Non-Human Primate: Potential Zoonotic Circulation and Long-Term Strain Persistence. [PDF]

Pathogens
Koumba Mavoungou DS, Boundenga L, Lekana-Douki SE, Pendy NML, Moukouama SEK, Kombila LB, Falque G, Mangombi JB, Mouinga-Ondeme A, Dedkov V, Dacheux L, Aghokeng AF, N'dilimabaka N.   +12 more
europepmc   +1 more source

Integrating tunable LED‐induced plant responses with novel solar cell technologies for energy‐efficient agrivoltaic systems

PLANTS, PEOPLE, PLANET, EarlyView.
The increasing demand for sustainable food production requires innovative solutions that balance productivity, resource efficiency, and environmental impact. Vertical Farming Systems (VFSs) offer a promising approach; however, their high energy consumption remains challenging.
Alessio Dessì, Carlo Spampinato, Fabiano Sillo, Salvatore Valastro, Mauro Centritto, Cecilia Brunetti, Andrea Ghirardo, Jörg‐Peter Schnitzler, Alessandra Alberti, Gianna Reginato, Aurora Rizzo, Raffaella Balestrini   +11 more
wiley   +1 more source

Ethnobotanical and genetic assessments of Central American avocado landraces reveal novel sources of biodiversity and ancient migration patterns

PLANTS, PEOPLE, PLANET, EarlyView.
Avocados are a multibillion‐dollar global commodity, but their growing export market pressures local farmers to abandon local fruit tree diversity in favor of commercial cultivar production. Interviews with rural avocado farmers and households from the Southern Mexican Highlands, Pacific Coastal Honduras, and Western Nicaragua, as well as the genetic ...
Kevin Wann, Heather B. Thakar, Courtney A. Hofman, Hector Neff, Logan Kistler   +4 more
wiley   +1 more source

Reported Cases and Deaths of National Notifiable Infectious Diseases - China, December 2025. [PDF]

China CDC Wkly
europepmc   +1 more source

Structural Insights Into the Function of Leishmania major Adenylosuccinate Lyase

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT One of several intriguing aspects of kinetoplastid biochemistry is the complete dependence on host purines and purine recycling due to the lack of a de novo purine biosynthesis pathway. Adenylosuccinate lyase (ASL, EC 4.3.2.2) is a key enzyme in the purine synthesis pathway responsible for the conversion of adenylosuccinate into adenosine ...
Ivan R. e Silva, Monique Mantovani, Maria E. S. D. Lino, Aline O. Albuquerque, João H. M. da Silva, Ronaldo A. P. Nagem, Adriana L. Rojas, Geraldo R. Sartori, Eduardo Horjales, David Campbell, Otavio H. Thiemann   +10 more
wiley   +1 more source

CXCR4-tropic HIV-1 infection in an immunocompetent monkey model. [PDF]

Nat Commun
Meyerson NR, Bauer VL, Fattor WT, Warren CJ, Barbachano-Guerrero A, Weiss MJ, Dirasantha O, Burris BL, Adesina AS, Timpona JL, Feldman ER, Fahy RT, Gendler P, Fainberg A, Nehete PN, Shelton KA, Galvan A, Tustin GW, Koehle PJ, Salinas MD, Davila O, Lindemann EI, Clark SE, Garnett ML, DeMarco CT, Scianna SR, Denny TN, Kuhn JH, Aye PP, Veazey RS, Kezar SM, Wilkerson GK, Sawyer SL.   +32 more
europepmc   +1 more source

Sodium Ions Affect GPR17 Conformational States and Functionality

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Sodium is an allosteric modulator of several class‐A GPCR regulating active versus inactive conformation state and may be a critical issue for the optimization of crystallization procedures. Herein, the role of Na+ in the regulation of GPR17 conformational states was studied through MD simulations of GPR17 wild‐type and mutated on two ...
Luca Palazzolo, Simona Daniele, Davide Bianchi, Lara Russo, Stefano Capaldi, Maria Letizia Trincavelli, Ivano Eberini   +6 more
wiley   +1 more source

Effects of bioinsecticide exposure route on aphids and their natural enemies in oilseed rape

Pest Management Science, EarlyView.
Fatty acids, silicone polymers and surfactants reduced aphid numbers but caused natural enemy mortality under direct exposure, while minimal residual activity suggests potential for targeted, compatible use in integrated pest management. Abstract BACKGROUND Myzus persicae Sulzer and Brevicoryne brassicae L.
Aimee J. Tonks, Tom W. Pope, Simon Cooper, Joe M. Roberts   +3 more
wiley   +1 more source