Diagnosis of Autoimmune Blistering Diseases
Frontiers in Medicine, 2018 Autoimmune skin blistering diseases (AIBD) are characterized by autoantibodies that are directed against structural proteins in the skin and adjacent mucous membranes.
M. Witte, D. Zillikens, E. Schmidt
semanticscholar +1 more source
Novel anti-tumour necrosis factor receptor-1 (TNFR1) domain antibody prevents pulmonary inflammation in experimental acute lung injury. [PDF]
, 2018 BACKGROUND: Tumour necrosis factor alpha (TNF-α) is a pleiotropic cytokine with both injurious and protective functions, which are thought to diverge at the level of its two cell surface receptors, TNFR1 and TNFR2.
core +2 more sources
Ancient hybridization and strong adaptation to viruses across African vervet monkey populations
Nature Genetics, 2016 Vervet monkeys are among the most widely distributed nonhuman primates, show considerable phenotypic diversity, and have long been an important biomedical model for a variety of human diseases and in vaccine research.
Hannes Svardal +21 more
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Large-scale survey to estimate the prevalence of disorders for 192 Kennel Club registered breeds [PDF]
, 2017 Background Pedigree or purebred dogs are often stated to have high prevalence of disorders which are commonly assumed to be a consequence of inbreeding and selection for exaggerated features.
Evans, K M +4 more
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eLife, 2012 Human hepatitis B virus (HBV) infection and HBV-related diseases remain a major public health problem. Individuals coinfected with its satellite hepatitis D virus (HDV) have more severe disease.
Huan Yan +19 more
semanticscholar +1 more source
1st INCF Workshop on Genetic Animal Models for Brain Diseases [PDF]
, 2011 The INCF Secretariat organized a workshop to focus on the “role of neuroinformatics in the processes of building, evaluating, and using genetic animal models for brain diseases” in Stockholm, December 13–14, 2009.
Holm Graessner, Olaf Riess
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Establishment and ultrasound characteristics of atherosclerosis in rhesus monkey
BioMedical Engineering OnLine, 2015 BackgroundAtherosclerosis is one of the main risk factors cause acute cerebral-cardio vascular diseases. It's of great significance to establish an atherosclerosis animal model that can mimic the characteristics and nature course of human patients ...
Wen Zeng +9 more
semanticscholar +1 more source
An experimental study on (131)I-CHIBA-1001: a radioligand for α7 nicotinic acetylcholine receptors. [PDF]
PLoS ONE, 2013 OBJECTIVE: The α7 nicotinic acetylcholine receptors (nAChRs) play a vital role in the pathophysiology of neuropsychiatric diseases such as Alzheimer's disease and depression.
Lei Yin +10 more
doaj +1 more source
Inferring collective dynamical states from widely unobserved systems
, 2018 When assessing spatially-extended complex systems, one can rarely sample the states of all components. We show that this spatial subsampling typically leads to severe underestimation of the risk of instability in systems with propagating events.
Priesemann, Viola, Wilting, Jens
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Comparative Analysis of Field-Isolate and Monkey-Adapted Plasmodium vivax Genomes
PLoS Neglected Tropical Diseases, 2015 Significant insights into the biology of Plasmodium vivax have been gained from the ability to successfully adapt human infections to non-human primates. P.
Ernest R. Chan +3 more
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