Results 41 to 50 of about 65,278 (164)

Establishment of a Rapid Lesion-Controllable Retinal Degeneration Monkey Model for Preclinical Stem Cell Therapy

Cells, 2020
Background: Retinal degenerative disorders (RDs) are the main cause of blindness without curable treatment. Our previous studies have demonstrated that human-induced pluripotent stem cells can differentiate into retinal organoids with all subtypes of ...
Guanjie Gao, Liwen He, Shengxu Liu, Dandan Zheng, Xiaojing Song, Wenxin Zhang, Minzhong Yu, Guangwei Luo, Xiufeng Zhong   +8 more
doaj   +1 more source

Genome-wide characterization of endogenous retroviruses in snub-nosed monkeys [PDF]

PeerJ, 2019
Background Endogenous retroviruses (ERV) are remnants of former exogenous retroviruses that had previously invaded the germ line of the host that can be vertically transmitted across generations. While the majority of ERVs lack infectious capacity due to
Xiao Wang, Boshi Wang, Zhijin Liu, Paul A. Garber, Huijuan Pan   +4 more
doaj   +2 more sources

Terahertz Spectroscopic Diagnosis of Myelin Deficit Brain in Mice and Rhesus Monkey with Chemometric Techniques

Scientific Reports, 2017
While myelin deficit of the central nervous system leads to several severe diseases, the definitive diagnostic means are lacking. We proposed and performed terahertz time-domain spectroscopy (THz-TDS) combined with chemometric techniques to discriminate ...
Yi Zou, Jiang Li, Yiyuan Cui, Peiren Tang, Lianghui Du, Tunan Chen, Kun Meng, Qiao Liu, Hua Feng, Jianheng Zhao, Mina Chen, Li-Guo Zhu   +11 more
doaj   +1 more source

Designing a solar powered automatic hand-dryer to combat the outbreak of ebola and monkey pox diseases in sub-Saharan Africa

Journal of Applied Sciences and Environmental Management, 2018
In recent times, the outbreak and the concomitant spread of Monkey pox and Ebola virus diseases across some countries of sub-Saharan Africa in electrifying waves was terrifying. The countries worst hit are Liberia, Sierra Leone, Ghana, and Nigeria.
U.K. Okpeki, A.O. Oyubu, A.U. Oyubu
doaj   +1 more source

Comparison of femtosecond laser-assisted corneal intrastromal xenotransplantation and the allotransplantation in rhesus monkeys

BMC Ophthalmology, 2017
Background In our previous study, we showed that both allogeneic and autogeneic small-incision femtosecond laser-assisted corneal intrastromal transplantation are safe and effective surgeries.
He Jin, Liangping Liu, Hui Ding, Miao He, Chi Zhang, Xingwu Zhong   +5 more
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Analysis of 10,000 ESTs from lymphocytes of the cynomolgus monkey to improve our understanding of its immune system

BMC Genomics, 2006
Background The cynomolgus monkey (Macaca fascicularis) is one of the most widely used surrogate animal models for an increasing number of human diseases and vaccines, especially immune-system-related ones.
Lin Ying, Wu Zhen-Qiang, He Xiao-Wei, Lin Wei, Wang Xue-Xia, Chen Wei-Hua, Hu Song-Nian, Wang Xiao-Ning   +7 more
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Monkeys excluding apes as a model for studies on metabolic syndrome

Бюллетень сибирской медицины
Aim. To summarize the results of research on metabolic syndrome in monkeys excluding apes and to conduct a comparison with humans.A search for full-text publications in PubMed and Scopus databases was carried out using the following keywords: nonhuman ...
S. V. Orlov, Yu. P. Uspensky, Yu. A. Fominykh, Yu. A. Kolesnik, A. V. Panchenko   +4 more
doaj   +1 more source

Homologous recombination-mediated targeted integration in monkey embryos using TALE nucleases

BMC Biotechnology, 2019
Background Non-human primate (NHP) models can closely mimic human physiological functions and are therefore highly valuable in biomedical research. Genome editing is now developing rapidly due to the precision and efficiency offered by engineered site ...
Chu Chu, Zhaohui Yang, Jiayin Yang, Li Yan, Chenyang Si, Yu Kang, Zhenzhen Chen, Yongchang Chen, Weizhi Ji, Yuyu Niu   +9 more
doaj   +1 more source

An Evaluation of the Safety and Immunogenicity of a Recombinant Protein-Based Pneumococcal Vaccine in ICR Mice and Cynomolgus Macaque Models

Vaccines
Background: Pneumococcal diseases remain a global threat due to the serotype-specific limitations of polysaccharide vaccines. This study evaluated a recombinant protein-based pneumococcal vaccine (PBPV) combining three PspA variants (PRX1/Family1Clade2 ...
Xiuwen Sui, Ying Yang, Qingfu Xu, Xiao Xu, Dongxia Zhang, Kang Li, Jiangjiao Li, Qingshan Mo, Junqiang Li, Bo Hao, Weixue Si, Jianming Shi, Zhongqi Shao, Xuefeng Yu, Tao Zhu   +14 more
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Toll-like Interleukin -1 Receptor Regulator (TILRR) Protein, a Major Modulator of Inflammation, is Expressed in Normal Human and Macaque Tissues and PBMCs

Journal of Inflammation Research, 2022
Mohammad Abul Kashem,1– 3 Lin Li,2 Xin-Yong Yuan,2 Francis A Plummer1 ,† Ma Luo1,2 1Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, MB, Canada; 2JC Wilt Infectious Diseases Research Center, National ...
Kashem MA, Li L, Yuan XY, Plummer FA, Luo M   +4 more
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