Results 111 to 120 of about 1,689,796 (314)

One‐Pot Isothermal Nucleic Acid Amplification Assisted CRISPR/Cas Detection Technology: Challenges, Strategies, and Perspectives

open access: yesAdvanced Science, Volume 12, Issue 37, October 6, 2025.
This review combines the current status of CRISPR (Clustered Regularly Interspaced Short Palindromic Repeat)‐based molecular diagnostic technology to expound the necessity and challenges faced in promoting the development of one‐pot detection. Besides, the focus is on a comprehensive summary and incisive analysis of emerging strategies for one‐pot ...
Hongyan Liu   +10 more
wiley   +1 more source

Insights into the Transmission, Host Range, Genomics, Vaccination, and Current Epidemiology of the Monkeypox Virus

open access: yesVeterinary Medicine International
This review delves into the historical context, current epidemiological landscape, genomics, and pathobiology of monkeypox virus (MPXV). Furthermore, it elucidates the present vaccination status and strategies to curb the spread of monkeypox.
Yusha Araf   +14 more
semanticscholar   +1 more source

Computer-assisted drug repurposing for thymidylate kinase drug target in monkeypox virus

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
Introduction Monkeypox is a zoonotic disease caused by brick-shaped enveloped monkeypox (Mpox) virus that belongs to the family of ancient viruses known as Poxviridae. Subsequently, the viruses have been reported in various countries.
Amar Ajmal   +10 more
semanticscholar   +1 more source

Public Health Threat of New, Reemerging, and Neglected Zoonoses in the Industrialized World [PDF]

open access: yes, 2010
Microbiologic infections acquired from animals, known as zoonoses, pose a risk to public health. An estimated 60% of emerging human pathogens are zoonotic. Of these pathogens, >71% have wildlife origins.
Cutler, S.J.   +2 more
core   +4 more sources

Design Strategies for Novel Lipid Nanoparticle for mRNA Vaccine and Therapeutics: Current Understandings and Future Perspectives

open access: yesMedComm, Volume 6, Issue 10, October 2025.
This review summarizes strategies to optimize lipid nanoparticles (LNPs) for improved targeting, endosomal escape, and safety. It highlights mRNA design, alternative delivery systems, and recent therapeutic advances across infectious diseases, cancer, and drug applications.
Xiaochi Li   +7 more
wiley   +1 more source

Detection of Monkeypox Virus DNA in Airport Wastewater, Rome, Italy

open access: yesEmerging Infectious Diseases, 2023
Environmental surveillance can be a complementary tool for detecting pathogens circulating in communities. We detected monkeypox virus DNA in wastewater from Italy’s largest airport by using real-time PCR assays targeting the G2R region and F3L and N3R ...
G. La Rosa   +6 more
semanticscholar   +1 more source

The outbreak of the monkeypox virus in the shadow of the pandemic

open access: yesEnvironmental Science and Pollution Research, 2023
The human monkeypox virus (MPXV) was first identified in 1959. Since then, the incidence of the disease has been sporadic. The endemic regions were identified in Africa's central and western areas. However, the infection started to spread in 2017 to non-endemic regions such as North and South America, Europe, and Asia.
Ankit Majie   +2 more
openaire   +2 more sources

Potential Risk of Local Transmission of Mpox in Nepal: An Emerging Public Health Concern

open access: yesHealth Science Reports, Volume 8, Issue 9, September 2025.
ABSTRACT Background and Aims Monkeypox (Mpox) is a zoonotic disease caused by the monkeypox virus, a double‐stranded DNA virus of the Orthopoxvirus genus with two major clades (Clades I and II), with Clade IIb responsible for most global cases reported during 2022–2024.
Yogendra Shah   +9 more
wiley   +1 more source

The re-emergence and transmission of Monkeypox virus in Nigeria: the role of one health

open access: yesFrontiers in Public Health
The Monkeypox virus, commonly abbreviated as mpox, is a viral zoonosis that is experiencing a resurgence in prevalence. It is endemic to regions of West and Central Africa that are characterized by dense forested areas.
S. C. Ogunleye   +12 more
semanticscholar   +1 more source

Panmicrobial oligonucleotide array for diagnosis of infectious diseases [PDF]

open access: yes, 2007
To facilitate rapid, unbiased, differential diagnosis of infectious diseases, we designed GreeneChipPm, a panmicrobial microarray comprising 29,455 sixty-mer oligonucleotide probes for vertebrate viruses, bacteria, fungi, and parasites.
Briese, Thomas   +23 more
core   +3 more sources

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