Results 1 to 10 of about 1,041,172 (171)

Isolation and identification of monkeypox virus MPXV-ROK-P1-2022 from the first case in the Republic of Korea [PDF]

Osong Public Health and Research Perspectives, 2022
Objectives Monkeypox outbreaks in nonendemic countries have been reported since early May 2022. The first case of monkeypox in the Republic of Korea was confirmed in a patient who traveled to Europe in June 2022, and an attempt was made to isolate and ...
Jin-Won Kim, Minji Lee, Hwachul Shin, Chi-Hwan Choi, Myung-Min Choi, Jee Woong Kim, Hwajung Yi, Cheon-Kwon Yoo, Gi-Eun Rhie   +8 more
doaj   +4 more sources

Monkeypox virus (MPXV) genomics: A mutational and phylogenomic analyses of B.1 lineages [PDF]

Travel Medicine and Infectious Disease, 2023
The recent increase in monkeypox (MPX) cases has attracted attention of public health authorities due to its quick spread and transmission across non-endemic regions. This outbreak, unlike previous ones, displays different epidemiological features and transmission dynamics, which appear to be largely influenced by the newly divergent MPX lineages (B.1).
Juan David Ramirez, Marina Munoz, D Katterine Bonilla-Aldana   +2 more
exaly   +4 more sources

Phylogenomic analysis of the monkeypox virus (MPXV) 2022 outbreak: Emergence of a novel viral lineage? [PDF]

Travel Medicine and Infectious Disease, 2022
Monkeypox is a zoonotic disease with clinical manifestations similar to smallpox in humans. Since May 13, 2022, an increasing number of suspected and confirmed cases have been reported, affecting non-endemic regions across the globe. More strikingly, reports from the current outbreak reveal unique aspects regarding transmission dynamics and an ...
Juan David Ramirez, Marina Munoz, D Katterine Bonilla-Aldana   +2 more
exaly   +4 more sources

Monkeypox virus (MPXV): A Brief account of global spread, epidemiology, virology, clinical features, pathogenesis, and therapeutic interventions [PDF]

Infectious Medicine, 2023
حدث أكبر تفشي لفيروس MPXV في القرن الحادي والعشرين في عام 2022، مما تسبب في أوبئة في العديد من البلدان. وفقًا لمنظمة الصحة العالمية، قد يكون الاتصال الجسدي مع الأشخاص المصابين أو الأسطح الملوثة أو الحيوانات المصابة مصدرًا لانتقال الفيروس. مرض حموي بما في ذلك بعض الأعراض الموجودة في مرض إم بي إكس.
Ahrar Khan, Md Atiqul Haque, Md Azizul Haque   +2 more
exaly   +5 more sources

Mpox Airborne Transmission: A Systematic Review. [PDF]

Rev Med Virol
ABSTRACT Since May 2022, mpox has been reported across multiple nonendemic regions, with concurrent outbreaks in diverse geographic settings, raising concerns about broader international spread. However, evidence regarding the risk of airborne transmission remains limited.
Theotonio Dos Santos LF, Arcuri LJ, Sant'Anna VAR, Couto PC, Schettino GPP, Rizzo LV, Fonseca HAR.   +6 more
europepmc   +2 more sources

One-Pot RPA-CRISPR/Cas12a Assay With Visual Readout for the Ultra-Specific Detection of Monkeypox Virus Clade I. [PDF]

Microb Biotechnol
This study established a rapid RPA‐CRISPR/Cas12a assay for MPXV clade I detection, achieving an LOD95 of 27.16 copies/μL within 40 min. The assay exhibited no cross‐reactivity with MPXV clade II or other orthopoxviruses. Under simulated conditions, the assay detected more low‐concentration plasmid‐spiked samples than quantitative polymerase chain ...
Li B, Liu L, Jin K, Huang Z, Zhang T, Gao R, Chen H, Niu L, Fan C, Zhang H, Huang P, Wang H.   +11 more
europepmc   +2 more sources

Evaluation of a portable multiplex real-time pcr assay for the detection of monkeypox virus and non-variola orthopoxviruses [PDF]

Virology Journal
Monkeypox (mpox) is the most significant orthopoxvirus (OPXV) infection in humans since smallpox eradication. The World Health Organization (WHO) has twice declared public health emergency of international concern due to the expansive spread of clade I ...
Shanshan Li, Nabojeet Das, Natalie Miller, Ariel Caudle, Kimberly Wilkins, Theodora Khan, Stefan Pfotenhauer, Amy Saunders, Christina L. Hutson, Kodumudi S. Venkateswaran, William M. Nelson, Neeraja Venkateswaran, Panayampalli S. Satheshkumar, Michael B. Townsend   +13 more
doaj   +2 more sources

Virtual Screening of Bacteriocins From Lactic Acid Bacteria Against Monkeypox DNA Polymerase: Sakacin P and Mundticin KS Emerge as Promising Candidates. [PDF]

Food Sci Nutr
This study employs an in silico virtual screening workflow to evaluate lactic acid bacteria (LAB)‐derived bacteriocins as potential inhibitors of the monkeypox virus DNA polymerase (MPDP). Protein‐peptide docking simulations using the HADDOCK platform revealed that Sakacin P and Mundticin KS possess the highest binding affinities for the MPDP target ...
Karaman MZ, Goel K, Zanchi FB, Ozdarendeli A, Mujwar S, Yetiman AE, Fidan O.   +6 more
europepmc   +2 more sources

A Global Health Alert on the Re-Emergence of Mpox a Viral Zoonotic Illness Its Prevention and Management: A Narrative Review. [PDF]

Health Sci Rep
ABSTRACT Background and Aims Monkeypox virus (MPXV) is gaining attention in the global health community due to its potential for human transmission and similarities to the well‐known smallpox virus. Mpox was first detected in the 1970s and mostly affects Central and West Africa.
Aqeel MB, Hanif A, Ahmad S, Shah FI, Javed B, Javed B, Iqbal S.   +6 more
europepmc   +2 more sources

Antifolate agent aminopterin demonstrates potent anti-monkeypox virus activity in vitro and in vivo [PDF]

Microbiology Spectrum
The ongoing spread of the monkeypox outbreak underscores the urgent need for the development of effective therapeutics against the monkeypox virus (MPXV).
Jing Wu, Meimei Duan, Lin Cheng, Deyan Chen   +3 more
doaj   +2 more sources