Results 21 to 30 of about 1,041,172 (171)
Monkeypox Virus in Nigeria: Infection Biology, Epidemiology, and Evolution [PDF]
Viruses, 2020 Monkeypox is a zoonotic disease caused by monkeypox virus (MPXV), which is a member of orthopoxvirus genus. The reemergence of MPXV in 2017 (at Bayelsa state) after 39 years of no reported case in Nigeria, and the export of travelers’ monkeypox (MPX ...
Emmanuel Alakunle +3 more
doaj +2 more sources
In-silico primer designing and PCR for detection of monkeypox virus (MPXV). [PDF]
J Infect Public Health, 2022 Khoo YW, Li S, Chong KP.
europepmc +4 more sources
Need for Vaccination Policies to Face Asymptomatic Monkeypox Virus Infection
Vaccines, 2022 The emergence of the monkeypox virus (MPXV) outbreak in 2022 represents a global threat to health [...]
Alexandre Vallée
doaj +2 more sources
Viruses, 2022 Monkeypox has been a neglected, zoonotic tropical disease for over 50 years. Since the 2022 global outbreak, hundreds of human clinical samples have been subjected to next-generation sequencing (NGS) worldwide with raw data deposited in public repositories. However, sequence analysis for in-depth investigation of viral evolution remains hindered by the
Jane Shen-Gunther, Hong Cai, Yufeng Wang
openaire +4 more sources
Dose-dependent pathogenicity and inflammatory imbalance in severely immunodeficient mice infected with mpox virus. [PDF]
Animal Model Exp MedThis study establishes an NPG (NOD.Cg‐Prkdcscid Il2rgtm1/Vst) mouse model for severe monkeypox virus infection in immunocompromised hosts, demonstrating dose‐dependent disease severity and revealing that unbalanced pro‐inflammatory cytokine release drives pathogenesis, providing insights for therapeutic interventions. Abstract The global spread of mpox
Li N +11 more
europepmc +2 more sources
A comprehensive review of monkeypox virus and mpox characteristics [PDF]
Frontiers in Cellular and Infection MicrobiologyMonkeypox virus (MPXV) is the etiological agent of monkeypox (mpox), a zoonotic disease. MPXV is endemic in the forested regions of West and Central Africa, but the virus has recently spread globally, causing outbreaks in multiple non-endemic countries ...
Emmanuel Alakunle +6 more
doaj +2 more sources
Transmissibility of Clade IIb Monkeypox Virus in Young Rabbits
MicroorganismsThe monkeypox virus (MPXV) has spread globally, posing a severe challenge to global public health. This study systematically evaluated the aerosol shedding dynamics of the epidemic Clade IIb MPXV strain in infected young rabbits, along with its direct ...
Zhaoliang Chen +9 more
doaj +2 more sources
International Journal of Infectious DiseasesIntroduction: Monkeypox virus (MPXV), a DNA virus in the genus Orthopoxvirus, causes the clinical disease mpox. Human-to-human transmission occurs, primarily through contact with infectious lesions. The cycle threshold (Ct) value at which mpox virus can be isolated varies in the literature.
Dr Helen Callaby +10 more
openaire +3 more sources
Updated Information on Monkeypox Virus (MPXV) Ophthalmic Disease.
JAMA Ophthalmol, 2023 europepmc +3 more sources
Proteomics-based vaccine targets annotation and design of subunit and mRNA-based vaccines for Monkeypox virus (MPXV) against the recent outbreak. [PDF]
Comput Biol Med, 2023 Monkeypox Virus (MPXV) is a growing public health threat with increasing cases and fatalities globally. To date, no specific vaccine or small molecule therapeutic choices are available for the treatment of MPXV disease. In this work, we employed proteomics and structural vaccinology approaches to design mRNA and multi-epitopes-based vaccines (MVC ...
Jin Y +7 more
europepmc +4 more sources