Results 11 to 20 of about 10,102 (222)

Evaluation and validation of an RT‐PCR assay for specific detection of monkeypox virus (MPXV)

open access: yesJournal of Medical Virology, 2022
AbstractMonkeypox virus (MPXV) is a zoonotic orthopoxvirus within the Poxviridae family. MPXV is endemic to Central and West Africa. However, the world is currently witnessing an international outbreak with no clear epidemiological links to travel or animal exposure and with ever‐increasing numbers of reported cases worldwide.
Alberto Paniz‐Mondolfi   +43 more
openaire   +4 more sources

Monkeypox virus (MPXV)

open access: yesWorld Journal of Advanced Research and Reviews, 2022
Monkeypox (MPXV) is a zoonosis with a double-origin DNA (DNA), caused by monkeypox virus, an orthopox virus and close relative of variola virus (smallpox). It was first reported in central Africa in 1970 and has historically affected some of the poorest and most marginalized communities in the world.
Abdulkareem Salman, Khudhair
openaire   +2 more sources

An immunoinformatic approach towards development of a potent and effective multi-epitope vaccine against monkeypox virus (MPXV)

open access: yesJournal of Biomolecular Structure and Dynamics, 2023
Monkeypox is a viral zoonotic disease, often transmitted to humans from animals. While the whole world is haggling with the COVID-19 pandemic, the emergence of the monkeypox virus (MPXV) arose as a new challenge to mankind. Till date, numerous cases related to the MPXV have been reported in several countries across the globe, but, its momentary ...
Sarbani Mishra   +6 more
openaire   +3 more sources

Human Monkeypox: A Comprehensive Overview of Epidemiology, Pathogenesis, Diagnosis, Treatment, and Prevention Strategies [PDF]

open access: yesPathogens, 2023
Monkeypox virus (MPXV) is an emerging zoonotic virus that belongs to the Orthopoxvirus genus and presents clinical symptoms similar to those of smallpox, such as fever and vesicular–pustular skin lesions.
Diana Emilia Martínez-Fernández   +6 more
doaj   +3 more sources

Defining antigen targets to dissect vaccinia virus (VACV) and Monkeypox virus (MPXV)-specific T cell responses in humans

open access: yesbioRxiv, 2022
AbstractThe current Monkeypox virus (MPXV) outbreak in non-endemic countries is raising concern about the pandemic potential of novel orthopoxviruses. Little is known regarding MPXV immunity in the context of MPXV infection or vaccination with Vaccinia-based vaccines (VACV).
Alba Grifoni   +9 more
openaire   +2 more sources

Complete Genome Sequence of Monkeypox Virus Strain MPXV-ROK-P1-2022 Isolated from the First Monkeypox Patient in the Republic of Korea

open access: yesMicrobiology Resource Announcements, 2022
We report the complete genome sequence of the monkeypox virus strain MPXV-ROK-P1-2022, isolated from the first patient diagnosed with monkeypox in the Republic of Korea in June 2022. The virus was fully sequenced on the Illumina MiSeq instrument, and the phylogenetic tree showed that the strain belongs to lineage B.1.1.
Chi-Hwan Choi   +7 more
openaire   +3 more sources

Monkeypox virus quadrivalent mRNA vaccine induces immune response and protects against vaccinia virus

open access: yesSignal Transduction and Targeted Therapy, 2023
Monkeypox has been declared a public health emergency by the World Health Organization. There is an urgent need for efficient and safe vaccines against the monkeypox virus (MPXV) in response to the rapidly spreading monkeypox epidemic.
Ye Sang   +15 more
doaj   +2 more sources

A Customized Monkeypox Virus Genomic Database (MPXV DB v1.0) for Rapid Sequence Analysis and Phylogenomic Discoveries in CLC Microbial Genomics

open access: yesViruses, 2022
Monkeypox has been a neglected, zoonotic tropical disease for over 50 years. Since the 2022 global outbreak, hundreds of human clinical samples have been subjected to next-generation sequencing (NGS) worldwide with raw data deposited in public repositories. However, sequence analysis for in-depth investigation of viral evolution remains hindered by the
Jane Shen-Gunther, Hong Cai, Yufeng Wang
openaire   +4 more sources

Ocular manifestations of Monkeypox virus (MPXV) infection with viral persistence in ocular samples: A case series

open access: yesInternational Journal of Infectious Diseases
We describe the clinical presentation and ocular viral dynamics in patients with Monkeypox virus-related ophthalmic disease (MPXROD).In this case series, we investigated five consecutive patients with confirmed mpox, diagnosed through a positive Monkeypox virus (MPXV) Polymerase Chain Reaction (PCR) test and presenting with ocular symptoms.
Luciana P.S. Finamor   +16 more
openaire   +4 more sources

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