The Journal of biological chemistry, 2008 Intestinal monoacylglycerol (MG) metabolism is well known to involve its anabolic reesterification to triacylglycerol (TG). We recently provided evidence for enterocyte MG hydrolysis and demonstrated expression of the monoacylglycerol lipase (MGL) gene in human intestinal Caco-2 cells and rodent small intestinal mucosa.
Su-Hyoun, Chon +3 more
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Targeting the Endocannabinoid Metabolic Enzymes to Reduce Inflammatory Pain [PDF]
, 2014 Pain is a debilitating condition that presents a problem of clinical relevance. Common analgesics include opioids and non-steroidal anti-inflammatory drugs (NSIADs).
Ghosh, Sudeshna
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Monoacylglycerol lipase reprograms lipid precursors signaling in liver disease
World Journal of Gastroenterology, 2020 Dietary oversupply of triglycerides represent the hallmark of obesity and connected complications in the liver such as non-alcoholic fatty liver disease and non-alcoholic steatohepatitis, which eventually progress to cirrhosis and hepatocellular carcinoma. Monoacylglycerol lipase is the last enzymatic step in the hydrolysis of triglycerides, generating
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Monoacylglycerol Lipase Is a Therapeutic Target for Alzheimer's Disease
Cell Reports, 2012 Alzheimer's disease (AD) is the most common cause of dementia among older people. There are no effective medications currently available to prevent and treat AD and halt disease progression. Monoacylglycerol lipase (MAGL) is the primary enzyme metabolizing the endocannabinoid 2-arachidonoylglycerol in the brain.
Chen, Rongqing +7 more
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Further characterization of a secreted lipase from the human pathogen Leishmania donovani by determining the effect of various metal ions on its enzymatic activity. [PDF]
, 2014 Leishmania donovani, a protozoan parasite, is the causative agent of the often fatal disease visceral leishmaniasis. The current treatments available are minimal and toxic to the patient.
Hoertz, Lana
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Перетворення триацилгліцеринів в неповні ацилгліцерини за допомогою ферментів [PDF]
, 2006 В статті розглянуто ферментативні перетворення триацилгліцеринів, а саме, моно- і діацилгліцеринів, відомих харчових емульгаторів, за допомогою реакції гліцеролізу. Виявлено найбільш ефективний ферментний препарат – це Novozym 435. Вибрано співвідношення
Гасюк, Лариса Василівна +5 more
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Biocatalysts based on lipases, their immobilization and characterization [PDF]
, 2012 Bakalárska práca sa zaoberá problematikou imobilizovaných enzýmov. V teoretickej časti sú zhrnuté najnovšie používané metódy imobilizácie, typy heterogénnych nosičov a taktiež praktické využitie imobilizovaných enzýmov v potravinárskom priemysle ...
Bančáková, Anna
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Heterocyclic Compounds as Monoacylglycerol Lipase (MAGL) Inhibitors [PDF]
ACS Medicinal Chemistry Letters, 2021 openaire +2 more sources
Synthesis of Monoacylglycerol Rich in Polyunsaturated Fatty Acids from Tuna Oil with Immobilized Lipase AK [PDF]
, 2007 H-Kittikun, Aran +2 more
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