Cannabis sativa and the endogenous cannabinoid system: therapeutic potential for appetite regulation [PDF]
, 2011 The herb Cannabis sativa (C. sativa) has been used in China and on the Indian subcontinent for thousands of years as a medicine. However, since it was brought to the UK and then the rest of the western world in the late 19th century, its use has been a ...
Adams +215 more
core +3 more sources
Caspase‐6 Controls Lipid and Energy Metabolism in Diet‐Induced Obesity
Advanced Science, Volume 13, Issue 21, 13 April 2026.This study reveals an unknown metabolic role of caspase‐6 beyond cell death. Caspase‐6 deficiency protects against HFD‐induced obesity by increasing energy expenditure, reducing inflammation, and improving glucose metabolism. Mechanistically, caspase‐6 cleaves PPARγ and SP1 to suppress ATGL expression.
Abhishek Gupta +7 more
wiley +1 more source
Pathological Roles of Astrocytes in Traumatic Brain Injury
CNS Neuroscience &Therapeutics, Volume 32, Issue 4, April 2026.TBI induces intrinsic astrocytic changes, including reactive astrogliosis, A1 and A2 polarization, ion channels activation, pathological edema, oxidative stress, and metabolic dysregulation. These injury‐responsive astrocytes regulate neuroinflammation and tissue remodeling through dynamic crosstalk with microglia, macrophages, vascular endothelial ...
Di Wu +7 more
wiley +1 more source
Evaluating FABP5 as a Therapeutic Target for Pain Management
European Journal of Pain, Volume 30, Issue 4, April 2026.ABSTRACT Background and Objective Fatty acid‐binding proteins (FABPs) are intracellular lipid transporters. Pharmacological inhibition of FABP5 is analgesic in preclinical visceral, inflammatory, neuropathic and joint pain models. Genetic knockout or knockdown of FABP5 induces analgesia in select visceral and inflammatory pain models.
William Warren +4 more
wiley +1 more source
Mechanisms of lipid malabsorption in Cystic Fibrosis: the impact of essential fatty acids deficiency [PDF]
, 2005 Affiliation: CHU-Sainte-Justine, Université de MontréalTransport mechanisms, whereby alimentary lipids are digested and packaged into small emulsion particles that enter intestinal cells to be translocated to the plasma in the form of chylomicrons, are ...
Drouin, Éric +3 more
core +2 more sources
Regulation of energy metabolism in skeletal muscle cells by PPARδ activation, in vitro exercise and perilipin 2 ablation [PDF]
, 2015 The prevalence of type 2 diabetes (T2D) has increased worldwide during the last decades. Obesity and accumulation of lipids in skeletal muscles are strongly associated with T2D.
Feng, Yuan Zeng
core +1 more source
Kinetic and Crystallization Behaviour of Palm Oil, Palm Kernel Oil and Their Lipase-Catalyzed Interestified Blends Using Viscometry [PDF]
, 2004 The oil crystallization induction time is an important kinetic parameter that provides fundamental information in elucidating their physical and chemical properties. The main criterion for the selection of technique in determining oil induction time is
Chen, Chit Way
core
Fatty acid profiles of the main lipid classes of green seaweeds from fish pond aquaculture [PDF]
, 2017 The lipid composition of five species of green seaweeds (Chaetomorpha linum, Rhizoclonium riparium, Ulva intestinalis, Ulva lactuca, and Ulva prolifera) grown in fish pond aquaculture systems was studied.
Bandarra +24 more
core +1 more source
Novel Aminocyclobutanes as Monoacylglycerol Lipase Modulators [PDF]
ACS Medicinal Chemistry Letters, 2022 openaire +2 more sources
Liver and extrahepatic contributions to postheparin serum lipase activity of the rat [PDF]
, 1974 The influence of the amount of heparin injected on the contributions of liver and of extrahepatic tissues to the lipase activity of postheparin serum of the rat was studied.
Hülsmann, W.C. (William) +1 more
core +1 more source