Results 81 to 90 of about 5,510 (189)

Role of prostacyclin in pulmonary hypertension [PDF]

, 2014
Date of Acceptance: 11/12/2014 This is an open access article distributed under the terms of the Creative Commons Attribution license CC BY-4.0, which permits unrestricted use, distribution and reproduction in any medium, provided the original work is ...
Ali FY, Butrous G, Chester AH, Geiger LE, Newsholme SJ, Nguyen H, Ruan CH, Smith WL, Whittaker N   +8 more
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Design, synthesis and biological evaluation of heterocyclic derivatives as potential MAGL inhibitors. [PDF]

, 2012
Facoltà di Farmacia Corso di laurea in Chimica e tecnologia farmaceutica; Relatore: prof.ssa C.Manera, dott.ssa F.Castelli; SSD: CHIM 08 Candidato: Gianfilippo Martello Titolo tesi: Design, synthesis and biological evaluation of heterocyclic derivatives ...
MARTELLO, GIANFILIPPO
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Interplay between n-3 and n-6 long-chain polyunsaturated fatty acids and the endocannabinoid system in brain protection and repair. [PDF]

, 2017
The brain is enriched in arachidonic acid (ARA) and docosahexaenoic acid (DHA), long-chain polyunsaturated fatty acids (LCPUFA) of the n-6 and n-3 series, respectively. Both are essential for optimal brain development and function.
A Artmann, A Berger, A Bilkei-Gorzo, A Chicca, A Nadjar, A Petroni, A Piyanova, A Tanimura, A Thomazeau, A Thomazeau, A Viader, AA Farooqui, AE Bonnet, AF Domenichiello, AJ Vecchio, AL Groeger, AM Fjell, AP Simopoulos, B Batetta, B Lands, B Lu, BM Fonseca, BN Ames, C Arnold, C Canugovi, C Cipollina, CD Breder, CD Buckley, CE Ramsden, CN Serhan, CN Serhan, CN Serhan, CN Serhan, CT Chen, D Bagga, D Ehninger, D Kempuraj, D Leung, D Piomelli, D Rueda, DK Nomura, E Lien, E Mantzioris, E Molina-Holgado, E Ryberg, EA Placzek, EM Novak, ES Onaivi, G Kaur, GA Garden, GF Grabner, H Sprecher, H Yang, H Yang, HG Kuhn, I Galve-Roperh, I Katona, I Matias, J Liu, JC DeMar Jr, JC Demar Jr, JE Tungen, JF Quinn, JL Harrison, JM Parent, JP Pan, JR Savinainen, JT Wood, JW Phillis, JY Xu, K Jin, K Tsuboi, K Yamagata, K Yurko-Mauro, KD Patel, KD Stark, KE Hopperton, KS Broughton, L Belayev, L Petrocellis De, M Alhouayek, M Aursnes, M Gabbs, M Gabrielli, M Kano, M Lafourcade, M Mecha, M Ouellet, M Perluigi, M Zhu, MA Rashid, MB Goncalves, ME Tremblay, MG Cascio, MK Gregory, MR Flock, MV Sofroniew, MV Sofroniew, N Murataeva, N Murataeva, N Stella, NG Bazan, NG Bazan, NG Bazan, NG Bazan, NR Yerram, P Urquhart, PE Castillo, PJ Jones, PK Yip, R Luostarinen, R Micha, R Yang, RJ Kulmacz, S Forsyth, S Watanabe, S Zelasko, SA Moore, SC Dyall, SC Dyall, SC Dyall, SC Dyall, SC Dyall, SC Strike, SE O’Sullivan, Simon C. Dyall, SN Lim, SU Kim, T Aguado, T Bartsch, T Cassano, T Cederholm, T Larrieu, T Takizawa, TVP Bliss, V Chhor, V Darsalia, V Marzo Di, V Marzo Di, V Smedt-Peyrusse De, W Jiang, WL Huang, X Chen, Y Marchalant, Y Takagi, Y Tian, YC Yung, ZZ Xu   +147 more
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Novel Oxazine Monoacylglycerol Lipase (MAGL) Inhibitors [PDF]

ACS Medicinal Chemistry Letters, 2021
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From Fertilisation to Implantation in Mammalian Pregnancy-Modulation of Early Human Reproduction by the Endocannabinoid System. [PDF]

, 2010
There is an increasing recognition that the endocannabinoid system is the crucial cytokine-hormone system regulating early human pregnancy. The synchronous development of the fertilized embryo and the endometrium to ensure timely implantation has been ...
Abel, Alger, Alpha Gebeh, Anthony H. Taylor, Aquila, Aquila, Aquila, Arnone, Barrett, Battista, Battista, Bisogno, Blankman, Bray, Bray, Carreau, Chabbert Buffet, Chmurzynska, Cobellis, Devane, Devane, Di Marzo, Di Marzo, Di Marzo, Dinh, El-Talatini, El-Talatini, Evers, Fonseca, Francavilla, Furuhashi, Geber, Gervasi, Godlewski, Gong, Grimaldi, Guo, Guzeloglu-Kayisli, Habayeb, Habayeb, Habayeb, Habayeb, Helliwell, Horne, Idris, Jonathon M. Willets, Justin C. Konje, Kaczocha, Katerina N. Bambang, Kim, Lambert, Larqué, Leung, Maccarrone, Maccarrone, Maccarrone, Maccarrone, Maccarrone, Maccarrone, Maccarrone, Maccarrone, Maccarrone, Maccarrone, Maccarrone, Maingret, Matsuda, Mechoulam, Mechoulam, Meizel, Muccioli, Munro, Newton, Nixon, O'Sullivan, Okamoto, Pan, Pandey, Paria, Paria, Paria, Paria, Paria, Park, Patricia Lam, Pestonjamasp, Piccini, Pierantoni, Ravinet Trillou, Regan, Rodriguez de Fonseca, Rodriguez de Fonseca, Ross, Rossato, Rossi, Schmid, Schuel, Schuel, Schuel, Schuel, Simiand, Sipe, Smith, Sofikitis, Sriraman, Sun, Tapia, Taylor, Taylor, Timothy H. Marczylo, Toth, Trabucco, Tsuboi, Tulay Karasu, Turco, Wang, Wang, Wang, Wang, Wang, Wang, Wang, Wei, Wenger, Wenger, Yamano, Yang   +125 more
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Intestinal monoacylglycerol metabolism: developmental and nutritional regulation of monoacylglycerol lipase and monoacylglycerol acyltransferase.

The Journal of biological chemistry, 2008
Intestinal monoacylglycerol (MG) metabolism is well known to involve its anabolic reesterification to triacylglycerol (TG). We recently provided evidence for enterocyte MG hydrolysis and demonstrated expression of the monoacylglycerol lipase (MGL) gene in human intestinal Caco-2 cells and rodent small intestinal mucosa.
Su-Hyoun, Chon, Yin Xiu, Zhou, Joseph L, Dixon, Judith, Storch   +3 more
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Monoacylglycerol lipase reprograms lipid precursors signaling in liver disease

World Journal of Gastroenterology, 2020
Dietary oversupply of triglycerides represent the hallmark of obesity and connected complications in the liver such as non-alcoholic fatty liver disease and non-alcoholic steatohepatitis, which eventually progress to cirrhosis and hepatocellular carcinoma. Monoacylglycerol lipase is the last enzymatic step in the hydrolysis of triglycerides, generating
openaire   +2 more sources

Monoacylglycerol Lipase Is a Therapeutic Target for Alzheimer's Disease

Cell Reports, 2012
Alzheimer's disease (AD) is the most common cause of dementia among older people. There are no effective medications currently available to prevent and treat AD and halt disease progression. Monoacylglycerol lipase (MAGL) is the primary enzyme metabolizing the endocannabinoid 2-arachidonoylglycerol in the brain.
Chen, Rongqing, Zhang, Jian, Wu, Yan, Wang, Dongqing, Feng, Guoping, Tang, Ya-Ping, Teng, Zhaoqian, Chen, Chu   +7 more
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Targeting the Endocannabinoid Metabolic Enzymes to Reduce Inflammatory Pain [PDF]

, 2014
Pain is a debilitating condition that presents a problem of clinical relevance. Common analgesics include opioids and non-steroidal anti-inflammatory drugs (NSIADs).
Ghosh, Sudeshna
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Monoacylglycerol lipase (MAGL) [PDF]

Science-Business eXchange, 2011
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