Results 11 to 20 of about 25,801 (174)

Pathophysiological Studies of Monoaminergic Neurotransmission Systems in Valproic Acid-Induced Model of Autism Spectrum Disorder

Biomedicines, 2022
Autism spectrum disorder (ASD) is a neurodevelopmental disorder with complex etiology. The core syndromes of ASD are deficits in social communication and self-restricted interests and repetitive behaviors.
Hsiao-Ying Kuo, Fu-Chin Liu
doaj   +1 more source

Synthesis and Biological Evaluation of O⁶-Aminoalkyl-Hispidol Analogs as Multifunctional Monoamine Oxidase-B Inhibitors towards Management of Neurodegenerative Diseases

Antioxidants, 2023
Oxidative catabolism of monoamine neurotransmitters by monoamine oxidases (MAOs) produces reactive oxygen species (ROS), which contributes to neuronal cells’ death and also lowers monoamine neurotransmitter levels.
Ahmed H. E. Hassan, Hyeon Jeong Kim, Keontae Park, Yeonwoo Choi, Suyeon Moon, Chae Hyeon Lee, Yeon Ju Kim, Soo Bin Cho, Min Sung Gee, Danbi Lee, Jong-Hyun Park, Jong Kil Lee, Jong Hoon Ryu, Ki Duk Park, Yong Sup Lee   +14 more
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The regulatory role of AP-2β in monoaminergic neurotransmitter systems: insights on its signalling pathway, linked disorders and theragnostic potential

Cell & Bioscience, 2022
Monoaminergic neurotransmitter systems play a central role in neuronal function and behaviour. Dysregulation of these systems gives rise to neuropsychiatric and neurodegenerative disorders with high prevalence and societal burden, collectively termed ...
Mohamed H. Al-Sabri, Maryam Nikpour, Laura E. Clemensson, Misty M. Attwood, Michael J. Williams, Mathias Rask-Anderson, Jessica Mwinyi, Helgi B. Schiöth   +7 more
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Long-term low-dose oxytetracycline potentially leads to neurobehavioural changes

Ecotoxicology and Environmental Safety, 2021
Trace levels of oxytetracycline (OTC)—a veterinary antibiotic and feed additive—are widespread in the environment. Studies revealed that OTC potentially impairs thyroid function, which may affect neurobehaviour; however, the impact of exposure to ...
Yushu Qiu, Kan Yu, Xiaogang Yu, Xiaoping Yi, Kang Cai, Huajun Li, Shanshan Xu, Weiye Wang, Lisu Huang   +8 more
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Imaging of Monoamine Neurotransmitters with Fluorescent Nanoscale Sensors [PDF]

ChemPlusChem, 2020
AbstractCells use biomolecules to convey information. For instance, neurons communicate by releasing chemicals called neurotransmitters, including several monoamines. The information transmitted by neurons is, in part, coded in the type and amount of neurotransmitter released, the spatial distribution of release sites, the frequency of release events ...
Meshkat Dinarvand, Sofia Elizarova, James Daniel, Sebastian Kruss   +3 more
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Pharmacological Modulation of Behaviour, Serotonin and Dopamine Levels in Daphnia magna Exposed to the Monoamine Oxidase Inhibitor Deprenyl

Toxics, 2021
This study assessed the effects of the monoamine oxidase (MAO) inhibitor deprenyl in Daphnia magna locomotor activity. The mechanisms of action of deprenyl were also determined by studying the relationship between behaviour, MAO activity and ...
Marina Bellot, Melissa Faria, Cristian Gómez-Canela, Demetrio Raldúa, Carlos Barata   +4 more
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Intracerebroventricular Administration of Interferon-Alpha Induced Depressive-Like Behaviors and Neurotransmitter Changes in Rhesus Monkeys

Frontiers in Neuroscience, 2020
Interferon-alpha (IFN-α) is a cytokine widely used in the treatment of brain cancers and virus infections with side effects including causing depression.
Zhifei Li, Zhaoxia Li, Xiaoman Lv, Zhaofu Li, Lei Xiong, Xintian Hu, Xintian Hu, Xintian Hu, Xintian Hu, Dongdong Qin, Dongdong Qin   +10 more
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A glial variant of the vesicular monoamine transporter is required to store histamine in the Drosophila visual system. [PDF]

PLoS Genetics, 2008
Unlike other monoamine neurotransmitters, the mechanism by which the brain's histamine content is regulated remains unclear. In mammals, vesicular monoamine transporters (VMATs) are expressed exclusively in neurons and mediate the storage of histamine ...
Rafael Romero-Calderón, Guido Uhlenbrock, Jolanta Borycz, Anne F Simon, Anna Grygoruk, Susan K Yee, Amy Shyer, Larry C Ackerson, Nigel T Maidment, Ian A Meinertzhagen, Bernhard T Hovemann, David E Krantz   +11 more
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Monoamine Levels and Parkinson’s Disease Progression: Evidence From a High-Performance Liquid Chromatography Study

Frontiers in Neuroscience, 2021
Parkinson’s disease (PD) is associated with dysfunction of monoamine neurotransmitter systems. We investigated changes in the levels of monoamine and their metabolites in PD patients, together with their association to clinical profiles.
Patsorn Wichit, Patsorn Wichit, Sekh Thanprasertsuk, Sekh Thanprasertsuk, Sekh Thanprasertsuk, Onanong Phokaewvarangkul, Onanong Phokaewvarangkul, Onanong Phokaewvarangkul, Roongroj Bhidayasiri, Roongroj Bhidayasiri, Roongroj Bhidayasiri, Saknan Bongsebandhu-phubhakdi, Saknan Bongsebandhu-phubhakdi   +12 more
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Genetic polymorphisms in monoamine neurotransmitter systems show only weak association with acute post-surgical pain in humans

Molecular Pain, 2006
Background Candidate gene studies on the basis of biological hypotheses have been a practical approach to identify relevant genetic variation in complex traits.
Lee Hyewon, Kim Hyungsuk, Rowan Janet, Brahim Jaime, Dionne Raymond A   +4 more
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