Results 31 to 40 of about 25,801 (174)
Ageing and Neurodegeneration – The Role of Neurotransmitters’ Activity [PDF]
International Journal Bioautomation, 2022 Disease and ageing are linked in many ways and especially by the mechanisms they share. For many diseases, the process of ageing is the main culprit leading to the pathology. Hence, it is crucial to understand the process of ageing, and its molecular and
Bonka Lozanska +3 more
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HIV-1 Infection and Central Monoamine Neurotransmitters [PDF]
American Journal of Infectious Diseases, 2007 Human immunodeficiency virus type 1 (HIV-1) enters the central nervous system (CNS) shortly after infection and gets localized in different brain regions, leading to various types of neuropathological problems. It has been hypothesized that HIV-1 infection mediated neuropathogenesis may also adversely affect the activity of the central monoamine ...
Adarsh M. Kumar +4 more
openaire +1 more source
Relationship between Hp infection and serum gastrointestinal hormones and monoamine neurotransmitter levels in patients with ulcerative colitis [PDF]
Xin yixueObjective To investigate the relationship between Helicobacter pylori （Hp） infection and serum gastrointestinal hormones and monoamine neurotransmitter levels in patients with ulcerative colitis.
Wang Ruixue, Zhang Feng, Zhang Qiang
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Frontiers in Behavioral Neuroscience, 2022 BackgroundLoss of estrogen due to menopause or ovarian resection is involved in the development of anxiety, which negatively impacts work productivity and quality of life. Estrogen modulates mood by binding to estrogen receptors in the brain.
Xiaofeng Liu +10 more
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Comprehensive Behavioral Analysis of Activating Transcription Factor 5-Deficient Mice
Frontiers in Behavioral Neuroscience, 2017 Activating transcription factor 5 (ATF5) is a member of the CREB/ATF family of basic leucine zipper transcription factors. We previously reported that ATF5-deficient (ATF5-/-) mice demonstrated abnormal olfactory bulb development due to impaired ...
Mariko Umemura +8 more
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Post-translational modifications of histone proteins by monoamine neurotransmitters
Current Opinion in Chemical Biology, 2023 Protein monoaminylation is a biochemical process through which biogenic monoamines (e.g., serotonin, dopamine, histamine, etc.) are covalently bonded to certain protein substrates via Transglutaminase 2, an enzyme that catalyzes the transamidation of primary amines to the γ-carboxamides of glutamine residues.
Amni, Al-Kachak, Ian, Maze
openaire +2 more sources
ChemElectroChemMonoamine neurotransmitters are essential for learning, mental alertness, emotions, and blood flow, among other functions. Fatal neurological disorders that signal the imbalance of these biomolecules in the human system include Parkinson's disease ...
Saheed E. Elugoke +3 more
doaj +1 more source
Advanced Science, EarlyView.The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang +15 more
wiley +1 more source
Advanced Science, EarlyView.Depression, a prevalent neuropsychiatric disorder with unclear pathogenesis, involves dysfunctional adenylyl cyclase 8 (Adcy8) as a key risk factor. Chronic stress selectively reduces Adcy8 expression in the dorsal CA1 (dCA1) neurons. Depletion of Adcy8 in dCA1 excitatory neurons induces depressive‐like behaviors by impairing neuronal excitability and ...
Zi‐Jie Liu +14 more
wiley +1 more source
Sensors, 2020 Carbon fiber-microelectrodes (CFMEs) have been the standard for neurotransmitter detection for over forty years. However, in recent years, there have been many advances of utilizing alternative nanomaterials for neurotransmitter detection with fast scan ...
Alexander Mendoza +4 more
doaj +1 more source