Results 241 to 250 of about 85,545 (297)
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2018
Monoamine oxidases A and B (MAO A and B) are mammalian flavoenzymes bound to the outer mitochondrial membrane. They were discovered almost a century ago and they have been the subject of many biochemical, structural and pharmacological investigations due to their central role in neurotransmitter metabolism.
Dale E, Edmondson, Claudia, Binda
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Monoamine oxidases A and B (MAO A and B) are mammalian flavoenzymes bound to the outer mitochondrial membrane. They were discovered almost a century ago and they have been the subject of many biochemical, structural and pharmacological investigations due to their central role in neurotransmitter metabolism.
Dale E, Edmondson, Claudia, Binda
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AGEING, MONOAMINES, AND MONOAMINE-OXIDASE LEVELS
The Lancet, 1972Abstract Monoamine oxidase (M.A.O.), noradrenaline (N.A.), serotonin (5-H.T.), and 5-hydroxyindoleacetic acid (5-H.I.A.A.) were measured in the hindbrains of 55 patients. Blood-platelet and plasma M.A.O. were also measured in 122 normal, control subjects. There was a marked increase in M.A.O.
E. Schleyer-Saunders +2 more
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Current Protocols in Toxicology, 2000
AbstractMonoamine oxidase catalyzes the oxidative deamination of primary aliphatic and aromatic amines and some secondary and tertiary amines, including the hormone and neurotransmitter amines epinephrine, dopamine, norepinephrine and serotonin. The two isoenzymes, MAO‐A and MAO‐B, differ according to substrate and inhibitor specificities. For example,
Keith F, Tipton +2 more
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AbstractMonoamine oxidase catalyzes the oxidative deamination of primary aliphatic and aromatic amines and some secondary and tertiary amines, including the hormone and neurotransmitter amines epinephrine, dopamine, norepinephrine and serotonin. The two isoenzymes, MAO‐A and MAO‐B, differ according to substrate and inhibitor specificities. For example,
Keith F, Tipton +2 more
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Acta Physiologica Scandinavica, 1972
AbstractHomogenates of the liver, the kidneys and the brain of the hedgehog, Erinaceus europaeus,. have been tested for monoamine oxidase activity. The enzyme was present in all 3 tissues, and the enzyme was found to act on all the substrates known to be oxidised by other mammalian sources of the enzyme.
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AbstractHomogenates of the liver, the kidneys and the brain of the hedgehog, Erinaceus europaeus,. have been tested for monoamine oxidase activity. The enzyme was present in all 3 tissues, and the enzyme was found to act on all the substrates known to be oxidised by other mammalian sources of the enzyme.
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Depression and monoamine oxidase
Progress in Neuro-Psychopharmacology, 19791. The first part of the paper is devoted to a critical review on the possible relationships between depression and monoamine oxidase. 2. This study describes the results of an investigation of MAO-activity in depression, using new approaches and methodology.
H, Coper +6 more
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Monoamine oxidases in development
Cellular and Molecular Life Sciences, 2012Monoamine oxidases (MAOs) are flavoproteins of the outer mitochondrial membrane that catalyze the oxidative deamination of biogenic and xenobiotic amines. In mammals there are two isoforms (MAO-A and MAO-B) that can be distinguished on the basis of their substrate specificity and their sensitivity towards specific inhibitors.
Chi Chiu, Wang +4 more
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Switching Monoamine Oxidase Inhibitors
Drug Intelligence & Clinical Pharmacy, 1985Substituting one monoamine oxidase inhibitor for another is recommended only after a drug-free interval to avoid hypertensive emergencies. The evidence and mechanism firmly supporting this caution is lacking. We report a case where monoamine oxidase inhibitors were substituted without apparent adverse consequences.
B L, True, B, Alexander, B, Carter
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Monoamine Oxidase Interactions
Journal of Clinical Psychopharmacology, 2023openaire +2 more sources
2015
Evidence for the genetic control of human MAO is now well established. The relationships of MAO activities to neuropsychiatric disorders or response to psychopharmacologic treatments are relatively unstudied. Preliminary findings from our own studies suggest that (1) blood MAO activity is a polygenically controlled trait; (2) there may be a subgroup of
D S, Robinson, A, Nies
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Evidence for the genetic control of human MAO is now well established. The relationships of MAO activities to neuropsychiatric disorders or response to psychopharmacologic treatments are relatively unstudied. Preliminary findings from our own studies suggest that (1) blood MAO activity is a polygenically controlled trait; (2) there may be a subgroup of
D S, Robinson, A, Nies
openaire +2 more sources