Results 141 to 150 of about 23,408 (219)

Lithium Dispensing Patterns in Dutch Youth: Prevalence, Incidence Dosages, and Duration of Use From 2011 to 2022

open access: yesBipolar Disorders, Volume 28, Issue 5, August 2026.
ABSTRACT Objective Bipolar disorder (BD) often emerges during mid‐adolescence and young adulthood, and leads to functional and social impairment, with a prevalence of 0.87% among Dutch youth. Lithium, the first‐line BD maintenance treatment, stabilizes mood, prevents suicide, and is well tolerated, yet its use has declined as long‐term second ...
Ravish N. Gangapersad   +8 more
wiley   +1 more source

Endothelium‐ and epithelium‐derived novel endogenous catecholamines as modulators of the autonomic nervous system

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 15, Page 4091-4110, August 2026.
Abstract Catecholamines are classically viewed as neuronal transmitters and adrenal hormones; however, accumulating evidence demonstrates that sources other than nerve fibres and adrenal medulla play a fundamental role in local organ regulation. Physiological paradoxes, such as preserved organ function after denervation or transplantation, challenge a ...
Mariana G. de Oliveira   +3 more
wiley   +1 more source

Design, Synthesis, and Biological Effect Studies of Novel Benzofuran-Thiazolylhydrazone Derivatives as Monoamine Oxidase Inhibitors. [PDF]

open access: yesACS Omega
Osmani Ye D   +9 more
europepmc   +1 more source

Towards the Prevention of Freezing of Gait in Parkinson's Disease

open access: yesEuropean Journal of Neuroscience, Volume 64, Issue 4, August 2026.
Freezing of gait (FOG) is a disabling complication of Parkinson's disease (PD) that remains difficult to treat. Targeting modifiable risk factors and implementing pleiotropic (lifestyle) interventions before FOG onset may potentially delay or prevent its development.
Anouk Tosserams   +3 more
wiley   +1 more source

Improvement in Quality of Life and Non‐Motor Symptoms Associated With OFF Episodes in People With Parkinson's Disease Treated With Inhaled Levodopa

open access: yesEuropean Journal of Neurology, Volume 33, Issue 8, August 2026.
The open prospective multicenter INLEVO‐LIFE PD study showed in 40 patients with Parkinson's disease after 3 months of use of inhaled levodopa for OFF episodes an improvement in health‐related quality of life (primary endpoint) and also, as highlighted data, an effect of at least 90 min after its administration not only on motor status (UPDRS‐III) but ...
Diego Santos García   +4 more
wiley   +1 more source

<i>In Vitro</i> and <i>In Silico</i> ADME-Tox Profiling and Safety Significance of Multifunctional Monoamine Oxidase Inhibitors Targeting Neurodegenerative Diseases. [PDF]

open access: yesACS Chem Neurosci, 2020
Więckowska A   +14 more
europepmc   +1 more source

Catecholamines Activate a Tumour Progression Program in Differentiated Tumour Hepatocytes

open access: yesLiver International, Volume 46, Issue 8, August 2026.
ABSTRACT Background and Aims The sympathetic nervous system is involved in the progression and aggressiveness of several cancers, including hepatocellular carcinoma (HCC). However, the specific effects of sympathetic innervation and catecholamines on tumour hepatocyte behaviour remain poorly understood.
Elise Lelou   +14 more
wiley   +1 more source

Type-B monoamine oxidase inhibitors in neurological diseases: clinical applications based on preclinical findings. [PDF]

open access: yesNeural Regen Res
Alborghetti M   +5 more
europepmc   +1 more source

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