Results 81 to 90 of about 23,408 (219)
Intramuscular pathways of maladaptation in overtraining syndrome
The Journal of Physiology, EarlyView.Abstract figure legend The transition from adaptive overreaching to maladaptive overtraining and mechanisms through which excessive training load can lead to performance decline. Four interconnected pathophysiological domains are highlighted: neural fatigue, involving both central and peripheral components such as altered sensory feedback and reflex ...
Emily Shorter +4 more
wiley +1 more source
Cannabinoid exposure during pregnancy: Cardiorespiratory effects and offspring outcomes
The Journal of Physiology, EarlyView.Abstract figure legend Prenatal exposure to cannabinoids has been investigated across human and animal studies to understand its impact on physiological development. Evidence suggests that early‐life cannabinoid exposure influence multiple developmental processes, extending beyond neurodevelopmental outcomes to potentially affect placental function ...
Luis Gustavo A. Patrone +1 more
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor +4 more
wiley +1 more source
Molecular Investigation of the Antitumor Effects of Monoamine Oxidase Inhibitors in Breast Cancer Cells. [PDF]
Biomed Res Int, 2023 Alkhawaldeh A, Bardaweel S.
europepmc +1 more source
Analytical Science Advances, Volume 7, Issue 2, December 2026.The pharmacological potential of the methanolic stem extract of Acampe papillosa is evaluated using in vivo and in silico approaches. The extract demonstrates significant anxiolytic, sedative, anti‐inflammatory, and antipyretic activities in experimental models, while molecular docking supports the observed biological effects through favorable ...
Qurratul Ain Sadia +10 more
wiley +1 more source
Dangers of Monoamine Oxidase Inhibitors [PDF]
BMJ, 1963 G T, SPENCER, S E, SMITH
openaire +2 more sources
Methamphetamine Enantiomers: From Chemical Synthesis to Biological Fate
Chirality, Volume 38, Issue 9, September 2026.Methamphetamine is an amphetamine‐type stimulant characterized by a single stereogenic center, resulting in two enantiomers, (R)‐(−)‐methamphetamine and (S)‐(+)‐methamphetamine, with distinct biological and pharmacological profiles. These forms exhibit differences in central nervous system activity, metabolism, excretion, and overall physiological ...
Larissa Pires do Espírito Santo +9 more
wiley +1 more source
Drug Development Research, Volume 87, Issue 6, September 2026.ABSTRACT Alzheimer's disease (AD) is a multifactorial neurodegenerative disorder for which single‐target therapies often provide insufficient benefit, motivating the development of multi‐target‐directed ligands (MTDLs). In this study, a novel series of benzimidazolone‐based hybrids incorporating piperazine, coumarin, and triazole moieties was designed,
Fatih Yılmaz +4 more
wiley +1 more source
Clinically Relevant Drug Interactions with Monoamine Oxidase Inhibitors. [PDF]
Health Psychol Res, 2022 Edinoff AN +8 more
europepmc +1 more source