Results 81 to 90 of about 817,997 (230)
Innovations in Obesity Treatment: Beyond Adipose Tissue Dysfunction
Obesity Reviews, EarlyView.Obesity drives chronic inflammation, insulin resistance, type 2 diabetes, and cancer development through adipocyte dysfunction. Addressing this multisystemic disorder requires integrated strategies beyond diet and exercise, such as thermogenesis activation via menthol or capsinoids and appetite control through GLP‐1/GIP agonists and neuromodulation to ...
Jesica Martínez‐Godfrey +7 more
wiley +1 more source
MoleculesMonoamine oxidase B (MAO-B) is a key enzyme in the mitochondrial outer membrane, pivotal for the oxidative deamination of biogenic amines. Its overexpression has been implicated in the pathogenesis of several cancers, including glioblastoma and ...
Iyman Alsaad +6 more
doaj +1 more source
, 1981 The article presents a short review of some of the properties of the acetylenic inhibitors of monoamine oxidase currently under investigation: clorgyline, (—)-deprenyl, pargyline and J-508. Their substrate-selective inactivation, mechanism of inhibition,
C J FOWLER, B A CALLINGHAM, L ORELAND
core +1 more source
, 2020 Monoamine oxidase B inhibitory activity is closely regulated by the interaction of the small molecules with the enzyme. It is therefore desirable to use theoretical approaches to design rational methods to develop new molecules to modulate specific ...
Mella J. +5 more
core +1 more source
Drug‐Induced Sialolithiasis—A Big‐Data Retrospective Study
Oral Diseases, EarlyView.ABSTRACT Background Sialolithiasis pathophysiology is multifactorial, with systemic medications often hypothesised as a key contributor, particularly in older adults (Drug‐Induced Sialolithiasis). However, robust evidence supporting this theory is limited.
Gal Avishai +5 more
wiley +1 more source
MONOAMINE OXIDASE A (MAOA), CHILDHOOD TRAUMA, ALCOHOLISM AND AGGRESSION [PDF]
, 2008 Women who have experienced childhood sexual abuse (CSA) have an increased risk of alcoholism and antisocial personality disorder (ASPD). Among males, a functional polymorphism (MAOA-LPR, monoamine oxidase A linked polymorphic region) in the promoter ...
DUCCI, FRANCESCA
core
Recent development of monoamine oxidase inhibitors
, 2005 The monoamine oxidases (MAO-A and MAO-B) are flavoenzymes located in the outer mitochondrial membrane responsible for the oxidative deamination of many endogenous and exogenous monoamines.
Fioravanti, R. +7 more
core +1 more source
Theories and Practices on Developing Various Models of Betel Quid Cessation in Taiwan
Oral Diseases, EarlyView.ABSTRACT Objective This review examines the development and outcomes of Taiwan's betel quid cessation models over two decades. Betel quid, the world's fourth most used psychoactive substance, receives far less cessation attention than tobacco. Methods We present a narrative synthesis of program evaluations and national implementation data from Taiwan ...
Ming‐Shinn Lee, Yi‐Jung Tsai
wiley +1 more source
Plant Biology, EarlyView.Iron oxide nanoparticles influence the growth, antioxidant capacity, and gene activity of Melissa officinalis subsp. officinalis plants in vitro, revealing their potential as modulators of secondary metabolism. Abstract Application of iron oxide nanoparticles (NP) (Fe3O4‐NPs) in plant biotechnology presents new opportunities for enhancing metabolic ...
E. Bektaş +5 more
wiley +1 more source
Physiological Reports, 2019 Serotonin (5‐HT) accumulates in the heart during myocardial ischemia and induces deleterious effects on the cardiomyocytes through receptor‐dependent and monoamine oxidase‐dependent pathways.
Takashi Sonobe +3 more
doaj +1 more source