Results 101 to 110 of about 817,997 (230)
Dangers of Monoamine Oxidase Inhibitors [PDF]
G T, SPENCER, S E, SMITH
openaire +2 more sources
A new class of powerful inhibitors of monoamine oxidase A
It is well established that 1-methyl-4-phenylpyridinium (MPP), the neurotoxic bioactivation product of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and most of its analogs are good competitive inhibitors of monoamine oxidase A, with K i values in
Jin, Yuan Zhen +4 more
core +1 more source
Abstract Suicidal ideation, depressive symptoms, anxiety, and sleep disturbance remain difficult to manage in psychiatric populations, and intermittent theta‐burst stimulation (iTBS) has emerged as an accelerated, non‐invasive neuromodulation strategy for these outcomes.
Muhammad Bilal +8 more
wiley +1 more source
Real‐Time Neurochemical Sensing in Zebrafish: Electrochemical and Fluorescent Approaches
The use of zebrafish has emerged as a powerful approach for real‐time neurochemical measurements. This review highlights recent advances in electrochemical and fluorescent sensing strategies that enable dynamic measurements in live preparations of this complex vertebrate. These complementary approaches provide new insights into neurochemical signaling,
Piyanka Hettiarachchi +2 more
wiley +1 more source
Characterizing the Behavior of Caenorhabditis elegans in Monoamine Oxidase Inhibitors
Comparing three different monoamine oxidase inhibitors and the behavioral response of mutant Caenorhabditis elegans. The mutant strain of worm is unable to produce four different modulatory monoamines: serotonin, dopamine, and tyramine ...
Becker, Riley
core +2 more sources
Molecular Investigation of the Antitumor Effects of Monoamine Oxidase Inhibitors in Breast Cancer Cells. [PDF]
Alkhawaldeh A, Bardaweel S.
europepmc +1 more source
Fluoxetine (Prozac) is a drug that is useful for treating depression and for studying serotonin system function in live brain tissue. Unfortunately, the use of fluoxetine tends to foul electrodes when using fast‐scan cyclic voltammetry. In this work, we evaluated an extended serotonin waveform as a useful approach for mitigating fouling by fluoxetine ...
Chase Stucky +7 more
wiley +1 more source
A scalable, traceable workflow integrating network pharmacology, activity‐guided separation, spectrum–effect analysis, and molecular simulation identifies cryptotanshinone as a major anti–Parkinson's disease constituent of Salvia miltiorrhiza. Its neuroprotective activity is linked to stable MAO‐B interactions, restoration of ATP levels, and enhanced ...
Xin Wang +5 more
wiley +1 more source
The organometallic route to benzylamine type monoamine oxidase inhibitors
N-Methyl-N-(2-propynyl)piperonylamine can be simultaneously lithiated at the terminal acetylenic and at that arom. position which is flanked by both the side chain and an oxygen atom. Under carefully established conditions, the metal occupying the latter
Schlosser, Manfred, Geneste, Herve
core +1 more source

