Results 111 to 120 of about 25,878 (248)
Plant Biology, EarlyView.Iron oxide nanoparticles influence the growth, antioxidant capacity, and gene activity of Melissa officinalis subsp. officinalis plants in vitro, revealing their potential as modulators of secondary metabolism. Abstract Application of iron oxide nanoparticles (NP) (Fe3O4‐NPs) in plant biotechnology presents new opportunities for enhancing metabolic ...
E. Bektaş +5 more
wiley +1 more source
Nitrogen heterocycles as potential monoamine oxidase inhibitors: Synthetic aspects
, 2014 The present review highlights the synthetic methods of monoamine oxidase inhibitors (MAO) belonging to a group of nitrogen heterocycles such as pyrazoline, indole, xanthine, oxadiazole, benzimidazole, pyrrole, quinoxaline, thiazole and other related ...
Patil, Pravin O. +3 more
core +1 more source
Intramuscular pathways of maladaptation in overtraining syndrome
The Journal of Physiology, EarlyView.Abstract figure legend The transition from adaptive overreaching to maladaptive overtraining and mechanisms through which excessive training load can lead to performance decline. Four interconnected pathophysiological domains are highlighted: neural fatigue, involving both central and peripheral components such as altered sensory feedback and reflex ...
Emily Shorter +4 more
wiley +1 more source
Leflunomide, a Reversible Monoamine Oxidase Inhibitor
Central Nervous System Agents in Medicinal Chemistry, 2016 A screening study aimed at identifying inhibitors of the enzyme, monoamine oxidase (MAO), among clinically used drugs have indicated that the antirheumatic drug, leflunomide, is an inhibitor of both MAO isoforms. Leflunomide inhibits human MAO-A and MAO-B and exhibits IC<sub>50</sub> values of 19.1 μM and 13.7 μM, respectively.
Petzer, Jacobus P., Petzer, Anél
openaire +3 more sources
The organometallic route to benzylamine type monoamine oxidase inhibitors
N-Methyl-N-(2-propynyl)piperonylamine can be simultaneously lithiated at the terminal acetylenic and at that arom. position which is flanked by both the side chain and an oxygen atom. Under carefully established conditions, the metal occupying the latter
Schlosser, Manfred, Geneste, Herve
core +1 more source
, 1981 The article presents a short review of some of the properties of the acetylenic inhibitors of monoamine oxidase currently under investigation: clorgyline, (—)-deprenyl, pargyline and J-508. Their substrate-selective inactivation, mechanism of inhibition,
C J FOWLER, B A CALLINGHAM, L ORELAND
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Cannabinoid exposure during pregnancy: Cardiorespiratory effects and offspring outcomes
The Journal of Physiology, EarlyView.Abstract figure legend Prenatal exposure to cannabinoids has been investigated across human and animal studies to understand its impact on physiological development. Evidence suggests that early‐life cannabinoid exposure influence multiple developmental processes, extending beyond neurodevelopmental outcomes to potentially affect placental function ...
Luis Gustavo A. Patrone +1 more
wiley +1 more source
CYCLIC ANALOGS OF MONOAMINE OXIDASE INHIBITORS: ARYLPYRAZOLIDINES.
, 1968 CYCLIC ANALOGS OF MONOAMINE OXIDASE INHIBITORS ...
MARTIN DAVID. BAUM (7985342)
core
The Journal of Physiology, EarlyView.Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor +4 more
wiley +1 more source
The Blue Delirium: Serotonin and Anticholinergic Toxicity in a 95‐Year‐Old Woman
Journal of the American Geriatrics Society, EarlyView.
Camila S. Badell +3 more
wiley +1 more source