Results 111 to 120 of about 817,997 (230)

Expression regulation of MAO isoforms in monocytic cells in response to Th2 cytokines [PDF]

open access: yes, 2005
Background: Th2-cytokines, such as interleukins-4 and –13 (IL-4, IL-13), have been identified as alternative stimuli of monocytes/macrophages. We have recently profiled the gene-expression pattern of IL-4-teated human peripheral monocytes and found that ...
Kuban, RJ   +4 more
core  

Design, Synthesis, and Biological Evaluation of Molecular Hybrids Incorporating Coumarin‐Pyrazole‐Linked Indolinone Derivatives With Antioxidant and Anti‐Alzheimer Properties

open access: yesChemistry &Biodiversity, Volume 23, Issue 11, November 2026.
ABSTRACT The increase in global life expectancy has resulted in a significant rise in the occurrence of Alzheimer's disease (AD), making it a critical public health burden. Therefore, there is an urgent need to create effective methods to prevent or slow down the progression of the disease.
Ahmed Sabt   +6 more
wiley   +1 more source

Treating hearts and minds: adverse cardiovascular effects of psychiatric medications

open access: yesTherapeutic Advances in Drug Safety
Cardiovascular disease (CVD) is one of the leading causes of death in patients with severe mental illness (SMI), being ~3.3 times higher than in the general population.
Asdaq Shabbir Raja   +5 more
doaj   +1 more source

Clinically Relevant Drug Interactions with Monoamine Oxidase Inhibitors. [PDF]

open access: yesHealth Psychol Res, 2022
Edinoff AN   +8 more
europepmc   +1 more source

Antidepressant Misuse in Esports: A Review of Pharmacology, Adverse Effects, Pharmacokinetics and Biomatrix‐Based Detection for Anti‐Doping Applications

open access: yesDrug Testing and Analysis, Volume 18, Issue 11, Page 1361-1373, November 2026.
This review highlights the misuse of antidepressants as potential cognitive‐enhancing agents in Esports. Despite pharmacological effects that overlap with those of psychostimulants, antidepressants remain an under‐recognised source of doping in Esports.
Kassim Ali Salum   +4 more
wiley   +1 more source

The State of the Art of Pyrazole Derivatives as Monoamine Oxidase Inhibitors and Antidepressant/Anticonvulsant Agents

open access: yes, 2011
Monoamine oxidase plays a significant role in the control of intracellular concentration of monoaminergic neurotransmitters or neuromodulators and dietary amines.
CARRADORI, Simone   +7 more
core   +1 more source

Obsessive–Compulsive Disorder: Comorbidity, Biomarkers, Circuits, and Treatment Strategies

open access: yesMedComm, Volume 7, Issue 11, November 2026.
OCD has a high comorbidity with other psychiatric conditions, among which anxiety is the most frequent one. The shared genetic biomarkers and common neural circuits underlying the co‐occurrence of OCD and anxiety pave a new path for understanding the pathogenic mechanism of OCD and suggest tailored and integrative treatment therapies for OCD from the ...
Xiao‐Yang Zhang   +9 more
wiley   +1 more source

Getting the balance right: Established and emerging therapies for major depressive disorders

open access: yesNeuropsychiatric Disease and Treatment, 2010
Bojana Perovic, Marija Jovanovic, Branislava Miljkovic, Sandra VezmarDepartment of Pharmacokinetics, Faculty of Pharmacy, University of Belgrade, SerbiaAbstract: Major depressive disorder (MDD) is a common and serious illness of our times, associated ...
Bojana Perovic   +3 more
doaj  

In Vitro Evaluation of Novel Furo[3,2-c]coumarins as Cholinesterases and Monoamine Oxidases Inhibitors

open access: yesMolecules
Coumarin represents a privileged structural motif that is quite common in nature-derived and synthetic bioactive molecules. Some of us have recently described the straightforward preparation of complex furo[3,2-c]coumarins through a sequential double ...
Mariagrazia Rullo   +10 more
doaj   +1 more source

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