Results 131 to 140 of about 9,063 (256)
Inhibition of chickpea seedling copper amine oxidases by tetraethylenepentamine [PDF]
Copper amine oxidases are important enzymes, which contribute to the regulation of monoand polyamine levels. Each monomer contains one Cu(II) ion and 2,4,5-trihydroxyphenylalanine (TPQ) as cofactors.
اسدی, اسداله +2 more
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British Journal of Pharmacology, Volume 183, Issue 7, Page 1539-1556, April 2026.Background and Purpose 3,4‐Methylenedioxymethamphetamine (MDMA), commonly known as ecstasy, is a psychostimulant with entactogenic properties and known to induce arousal and euphoria. As an amphetamine derivate, MDMA acts on the monoamine systems in the brain and stimulates release of dopamine (DA), noradrenaline (NA) and serotonin (5‐HT), yet their ...
Tianhua Wang +2 more
wiley +1 more source
International Journal of Mental Health Nursing, Volume 35, Issue 2, April 2026.ABSTRACT The game changers in mental health and substance use disorder treatment have been shaped by historical sea changes marked by transformative advancements that have significantly enhanced patient care. Breakthroughs in psychotherapy, psychosurgery and psychopharmacology have each contributed to reshaping clinical practices, especially the ...
Arlene Kent‐Wilkinson +2 more
wiley +1 more source
Monoamine Oxidases Desensitize Intracellular β1AR Signaling in Heart Failure. [PDF]
Circ Res, 2021 Wang Y +8 more
europepmc +1 more source
The FASEB Journal, Volume 40, Issue 5, 15 March 2026.In SH‐SY5Y cells, Methylglyoxal (MGO) reduces the intracellular dopamine content, up‐regulating the expression of proteins that modulate dopamine amount (MAO‐B, COMT, and α‐Syn). The MGO‐induced increase of COMT and α‐Syn expression is mediated by the reduction of miR‐214 and miR‐190a levels.
Alessandra Croce +9 more
wiley +1 more source
Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.Abstract INTRODUCTION Clarifying relationships between amyloid, tau, and cognition is crucial to understanding dementia risk, but has been mainly performed in non‐Hispanic White (NHW) participants. It is unknown whether findings are generalizable to other ethnoracial groups.
Koral V. Wheeler +49 more
wiley +1 more source
Neuroprotective Function of Rasagiline and Selegiline, Inhibitors of Type B Monoamine Oxidase, and Role of Monoamine Oxidases in Synucleinopathies. [PDF]
Int J Mol Sci, 2022 Naoi M, Maruyama W, Shamoto-Nagai M.
europepmc +1 more source
Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.Abstract Neuromodulatory subcortical systems (NSSs) are uniquely susceptible to dementia‐related pathology, leading to frequent molecular and behavioral impairments associated with altered function of these nuclei. Some of these systems display clear sex‐specific cytoarchitecture and signaling leading to distinct physiology and behavioral outputs in ...
Rosaria J. Rae +53 more
wiley +1 more source
An efficient method to access spiro pseudoindoxyl ketones: evaluation of indoxyl and their N-benzylated derivatives for inhibition of the activity of monoamine oxidases. [PDF]
RSC Adv, 2023 Perumal K +6 more
europepmc +1 more source
Archiv der Pharmazie, Volume 359, Issue 3, March 2026.A novel pyrazoline derivative (P2) was synthesized and demonstrated potent α‐glucosidase inhibition (IC50 = 2.10 µM), significantly surpassing acarbose and highlighting its promise as an effective oral antidiabetic agent. ABSTRACT This study reports the synthesis of some novel chalcone (C1–C3) and 3,5‐disubstituted pyrazoline derivatives (P1–P3 ...
Fatma Erbay +6 more
wiley +1 more source