Results 11 to 20 of about 35,566 (181)
From warrior genes to translational solutions: novel insights into monoamine oxidases (MAOs) and aggression [PDF]
Translational Psychiatry, 2021 The pervasive and frequently devastating nature of aggressive behavior calls for a collective effort to understand its psychosocial and neurobiological underpinnings. Regarding the latter, diverse brain areas, neural networks, neurotransmitters, hormones,
Alexios-Fotios A. Mentis +3 more
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Central Effects of 3-Iodothyronamine Reveal a Novel Role for Mitochondrial Monoamine Oxidases [PDF]
Frontiers in Endocrinology, 2018 3-Iodothyronamine (T1AM) is the last iodinated thyronamine generated from thyroid hormone alternative metabolism found circulating in rodents and in humans. So far, the physiopathological meaning of T1AM tissue levels is unknown. Much is instead known on
Annunziatina Laurino +2 more
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Neuroprotective Function of Rasagiline and Selegiline, Inhibitors of Type B Monoamine Oxidase, and Role of Monoamine Oxidases in Synucleinopathies. [PDF]
Int J Mol Sci, 2022 Synucleinopathies are a group of neurodegenerative disorders caused by the accumulation of toxic species of α-synuclein. The common clinical features are chronic progressive decline of motor, cognitive, behavioral, and autonomic functions.
Naoi M, Maruyama W, Shamoto-Nagai M.
europepmc +2 more sources
Correction: From warrior genes to translational solutions: novel insights into monoamine oxidases (MAOs) and aggression [PDF]
Translational Psychiatry, 2021 Alexios-Fotios A. Mentis +3 more
doaj +2 more sources
Journal of Pharmacological Sciences, 2021 The orexinergic system plays a significant role in regulating proper sleep/wake maintenance. Dual orexin receptor antagonist (DORA) is widely prescribed for insomnia symptoms. The antagonist acts on orexin 1 and 2 receptors located in certain brain areas,
Shunpei Moriya +5 more
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Questions in the Chemical Enzymology of MAO
Chemistry, 2021 We have structure, a wealth of kinetic data, thousands of chemical ligands and clinical information for the effects of a range of drugs on monoamine oxidase activity in vivo.
Rona R. Ramsay, Alen Albreht
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Frontiers in Pharmacology, 2021 Mucosal epithelial cell integrity is an important component of innate immunity and it protects the host from an environment rich in microorganisms. Virulence factors from Gram-negative bacteria [e.g.
Edward E. Putnins +2 more
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Antioxidants, 2023 Oxidative catabolism of monoamine neurotransmitters by monoamine oxidases (MAOs) produces reactive oxygen species (ROS), which contributes to neuronal cells’ death and also lowers monoamine neurotransmitter levels.
Ahmed H. E. Hassan +14 more
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Ageing and Neurodegeneration – The Role of Neurotransmitters’ Activity [PDF]
International Journal Bioautomation, 2022 Disease and ageing are linked in many ways and especially by the mechanisms they share. For many diseases, the process of ageing is the main culprit leading to the pathology. Hence, it is crucial to understand the process of ageing, and its molecular and
Bonka Lozanska +3 more
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A twenty-year journey exploring coumarin-based derivatives as bioactive molecules
Frontiers in Chemistry, 2022 The coumarin core (i.e., 1-benzopyran-2 (2H)-one) is a structural motif highly recurrent in both natural products and bioactive molecules. Indeed, depending on the substituents and branching positions around the byciclic core, coumarin-containing ...
Leonardo Pisani +8 more
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