Results 31 to 40 of about 35,566 (181)

Altered activities of monoamine oxidase a in omani autistic children – a brief report [PDF]

International Journal of Biological and Medical Research, 2011
Autism spectrum disorder (ASD) is a mysterious neurodevelpomental disorder with onset prior to 3 years of age. Monoamine oxidases (MAO) A and B are the enzymes expressed in brain and able to metabolize dopamine, norepinephrine, epinephrine, and serotonin.
Essa MM , Al-Sharbati MM, Al-Farsi YM , Ali A , Waly MI , Al-Shaffae MA , Gilles GJ   +1 more
doaj  

Monoamine Oxidase (MAO) as a Potential Target for Anticancer Drug Design and Development

Molecules, 2021
Monoamine oxidases (MAOs) are oxidative enzymes that catalyze the conversion of biogenic amines into their corresponding aldehydes and ketones through oxidative deamination.
Reem Aljanabi, Lina Alsous, Dima A. Sabbah, Halise Inci Gul, Mustafa Gul, Sanaa K. Bardaweel   +5 more
doaj   +1 more source

Calcium ions alter monoamine oxidase A activity [PDF]

, 2013
S. Armstrong graduated from the University of St Andrews in 2011Activation of the flavoprotein monoamine oxidase A (MAO A) by calcium ions has been reported in isolated mitochondria, in cell lines, and in vivo. Enhanced MAO A activity has been associated
Ramsay, Rona R., Armstrong, Stephanie
core   +2 more sources

Coumarin analogue 3-methyl-7H-furo[3,2-g] chromen-7-one as a possible antiparkinsonian agent

Biomédica: revista del Instituto Nacional de Salud, 2019
Introduction: Parkinson’s disease is the second most common neurodegenerative disease. Monoamine oxidase B inhibitors are used in the treatment of this disease concomitantly with levodopa or as monotherapy.
María del Pilar Olaya, Nadezdha Esperanza Vergel, José Luis López, María Dolores Viña, Mario Francisco Guerrero   +4 more
doaj   +1 more source

MONOAMINE OXIDASE A (MAOA), CHILDHOOD TRAUMA, ALCOHOLISM AND AGGRESSION [PDF]

, 2008
Women who have experienced childhood sexual abuse (CSA) have an increased risk of alcoholism and antisocial personality disorder (ASPD). Among males, a functional polymorphism (MAOA-LPR, monoamine oxidase A linked polymorphic region) in the promoter ...
DUCCI, FRANCESCA
core   +1 more source

Histamine signaling and metabolism identify potential biomarkers and therapies for lymphangioleiomyomatosis

EMBO Molecular Medicine, 2021
Inhibition of mTOR is the standard of care for lymphangioleiomyomatosis (LAM). However, this therapy has variable tolerability and some patients show progressive decline of lung function despite treatment.
Carmen Herranz, Francesca Mateo, Alexandra Baiges, Gorka Ruiz de Garibay, Alexandra Junza, Simon R Johnson, Suzanne Miller, Nadia García, Jordi Capellades, Antonio Gómez, August Vidal, Luis Palomero, Roderic Espín, Ana I Extremera, Eline Blommaert, Eva Revilla‐López, Berta Saez, Susana Gómez‐Ollés, Julio Ancochea, Claudia Valenzuela, Tamara Alonso, Piedad Ussetti, Rosalía Laporta, Antoni Xaubet, José A Rodríguez‐Portal, Ana Montes‐Worboys, Carlos Machahua, Jaume Bordas, Javier A Menendez, Josep M Cruzado, Roser Guiteras, Christophe Bontoux, Concettina La Motta, Aleix Noguera‐Castells, Mario Mancino, Enrique Lastra, Raúl Rigo‐Bonnin, Jose C Perales, Francesc Viñals, Alvaro Lahiguera, Xiaohu Zhang, Daniel Cuadras, Coline H M van Moorsel, Joanne J van der Vis, Marian J R Quanjel, Harilaos Filippakis, Razq Hakem, Chiara Gorrini, Marc Ferrer, Aslihan Ugun‐Klusek, Ellen Billett, Elżbieta Radzikowska, Álvaro Casanova, María Molina‐Molina, Antonio Roman, Oscar Yanes, Miquel A Pujana   +56 more
doaj   +1 more source

Recent progress in directed evolution of stereoselective monoamine oxidases

Bioresources and Bioprocessing, 2019
Monoamine oxidases (MAOs) use molecular dioxygen as oxidant to catalyze the oxidation of amines to imines. This type of enzyme can be employed for the synthesis of primary, secondary, and tertiary amines by an appropriate deracemization protocol ...
Jiaqi Duan, Beibei Li, Youcai Qin, Yijie Dong, Jie Ren, Guangyue Li   +5 more
doaj   +1 more source

Brunner syndrome associated MAOA mutations result in NMDAR hyperfunction and increased network activity in human dopaminergic neurons

Neurobiology of Disease, 2022
Monoamine neurotransmitter abundance affects motor control, emotion, and cognitive function and is regulated by monoamine oxidases. Among these, Monoamine oxidase A (MAOA) catalyzes the degradation of dopamine, norepinephrine, and serotonin into their ...
Jon-Ruben van Rhijn, Yan Shi, Maren Bormann, Britt Mossink, Monica Frega, Hatice Recaioglu, Marina Hakobjan, Teun Klein Gunnewiek, Chantal Schoenmaker, Elizabeth Palmer, Laurence Faivre, Sarah Kittel-Schneider, Dirk Schubert, Han Brunner, Barbara Franke, Nael Nadif Kasri   +15 more
doaj   +1 more source

Past, Present and Future Anti-Obesity Effects of Flavin-Containing and/or Copper-Containing Amine Oxidase Inhibitors

Medicines, 2019
Background: Two classes of amine oxidases are found in mammals: those with a flavin adenine dinucleotide as a cofactor, such as monoamine oxidases (MAO) and lysine-specific demethylases (LSD), and those with copper as a cofactor, including copper ...
Christian Carpéné, Nathalie Boulet, Alice Chaplin, Josep Mercader   +3 more
doaj   +1 more source

Identification of a Lactic Acid Bacteria to Degrade Biogenic Amines in Chinese Rice Wine and Its Enzymatic Mechanism

Foods, 2019
A L. plantarum, CAU 3823, which can degrade 40% of biogenic amines (BAs) content in Chinese rice wine (CRW) at the end of post-fermentation, was selected and characterized in this work.
Tianjiao Niu, Xing Li, Yongjie Guo, Ying Ma   +3 more
doaj   +1 more source