Results 281 to 290 of about 1,153,626 (336)

Application of monoclonal antibodies in diabetes: A bibliometric analysis from 2004-2024. [PDF]

Hum Vaccin Immunother
Wei R, Jia B, Zheng S, Zhang X, Wang M, Sun N, Zhang R, Li Q.   +7 more
europepmc   +1 more source

Platelet Rubicon Bidirectional Regulation of GPVI and Integrin αIIbβ3 Signaling Mitigates Stroke Infarction Without Compromising Hemostasis

Advanced Science, EarlyView.
This study identifies Rubicon as a key platelet protein that bidirectionally regulates GPVI and integrin αIIbβ3 signaling. Platelet Rubicon protects against cerebral ischemia‐reperfusion injury by limiting infarction without increasing hemorrhage.
Xiaoyan Chen, Jingke Li, Yangyang Liu, Li Li, Xin Deng, Yilin Sheng, Xianyu Zhu, Xiao Jiang, Wei Li, Xueli Cai, Qiming Sun, Hu Hu   +11 more
wiley   +1 more source

Burden of severe asthma in Italy: Patients treated with versus eligible for monoclonal antibodies in a large real-world study. [PDF]

J Int Med Res
Dondi L, Ronconi G, Calabria S, Dell'Anno I, Dondi L, Addesi A, Esposito I, Canonica GW, Martini N, Piccinni C.   +9 more
europepmc   +1 more source

Targeted Inhibition of CD74+ Macrophages by Luteolin via CEBPB/P65 Signaling Ameliorates Osteoarthritis Progression

Advanced Science, EarlyView.
This study identifies CD74⁺ macrophages as key drivers of synovial inflammation in osteoarthritis (OA). The flavonoid luteolin is predicted to inhibit this pathway by blocking Nuclear Factor Kappa‐light‐chain‐enhancer of Activated B cells (NF‐κB) signaling. To enhance delivery, a targeted nanoplatform (MDSPL) is developed.
Rui Peng, Bo Yu, Lei Zhang, Zhaowen Xue, Lutian Yao, Qingjun Yang, Zitao Liu, Sizhi Wu, Yongquan Huang, Xiaofei Zheng, Huiying Guo, Songwei Huan, Tao Jiang, Huajun Wang, Yulong Wei, Tao Gui   +15 more
wiley   +1 more source

The Efficacy and Safety of Four Novel PCSK9 Monoclonal Antibodies in Patients With Hypercholesterolemia: A Systematic Review With Network Meta-Analysis and Trial Sequential Analysis. [PDF]

Cardiovasc Ther
Wang S, Li C, Fan D.
europepmc   +1 more source

Therapeutic administration of a recombinant human monoclonal antibody reduces the severity of chikungunya virus disease in rhesus macaques [PDF]

, 2017
Diamond, Michael S, et al,, Fox, Julie M, Sukulpovi-Petty, Soila   +3 more
core   +1 more source

Monoclonal Antibodies as a Breakthrough in Personalised Leukaemia Therapy: What Pharmacists and Doctors Should Know. [PDF]

Pharmacy (Basel)
Ryzhuk A, Kovalenko SM, Georgiyants M, Vysotska K, Georgiyants V.   +4 more
europepmc   +1 more source

Prediction of aggregation in monoclonal antibodies from molecular surface curvature. [PDF]

Sci Rep
Knez B, Erzin L, Kos Ž, Kuzman D, Ravnik M.   +4 more
europepmc   +1 more source

Do Anti-PCSK9 Monoclonal Antibodies Have Pleiotropic Effects? [PDF]

JACC Basic Transl Sci
Ferri N.
europepmc   +1 more source

The impact of CGRP monoclonal antibodies on cytokine expression in chronic migraine: a cohort study. [PDF]

J Neurol
Ray JC, McDonald S, Todaro M, Baker J, Yeh WZ, Hutton EJ, Matharu M, Butzkueven H.   +7 more
europepmc   +1 more source