Results 161 to 170 of about 801,490 (249)

Prolongation of Allograft Survival by Administration of Anti-CD45RB Monoclonal Antibody Is Due to Alteration of CD45RBhi: CD45RBlo T-Cell Proportions [PDF]

, 2006
Patrick Luke, Jianchuan Deng, D. Lian, Peta J. O’Connell, B. García, Anthony M. Jevnikar, Robert Zhong   +6 more
openalex   +1 more source

Platelet Lysate–Enriched Human Induced Pluripotent Stem Cell–Derived Chondrocyte Sheets for Bone Defect Repair via Endochondral Ossification

Advanced Healthcare Materials, EarlyView.
Human iPSC‐derived hypertrophic chondrocyte sheet promotes bone regeneration. Abstract Bone defects are a major clinical challenge, primarily owing to the limited self‐healing capacity of bones and the high risk of complications associated with conventional treatment strategies.
Yiwei Chen, Jiali Lin, Jiapeng Li, Yiwei Hu, Jiansen Su, Yu Miao, Lanlan Wang, Qian Tang, Changqing Zhang, Junhui Yin   +9 more
wiley   +1 more source

Caninized PD-1 monoclonal antibody in oral malignant melanoma: efficacy and exploratory biomarker analysis. [PDF]

J Immunother Cancer
Igase M, Hagimori K, Inanaga S, Mizoguchi H, Itamoto K, Sakurai M, Motegi T, Yamamoto H, Kato M, Shiga T, Tsukui T, Kobayashi T, Mizuno T.   +12 more
europepmc   +1 more source

The Lock and Key of Medicine: Monoclonal Antibodies and the Transformation of Healthcare

, 2015
Scott H. Podolsky
openalex   +1 more source

Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs

Advanced Healthcare Materials, EarlyView.
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner, Stefan Keim, Soheil Haddadzadegan, Odile Fernandez Romero, Katrin Zöller, Gabriel Stern, Ilaria Cesi, Krum Kafedjiiski, Andreas Bernkop‐Schnürch   +8 more
wiley   +1 more source

Optimising Monoclonal Antibody Drug Development for Inflammatory Bowel Disease. [PDF]

Clin Exp Gastroenterol
Colwill M, Honap S, Danese S, Peyrin-Biroulet L.   +3 more
europepmc   +1 more source

Fibrillar Bundles as Fibrous Filler Materials for Attaining Cell Anisotropy in Bioprinting

Advanced Healthcare Materials, EarlyView.
Fibrillar bundles are introduced as a bioprintable additive that enables robust and scalable cellular alignment within 3D constructs through flow‐induced orientation during extrusion. These fibers support strong cell adhesion and polarization across various cell types and significantly enhance myotube alignment in Gelatine‐Methacryloyl (GelMA ...
Sven Heilig, Zan Lamberger, Lys Sprenger, Vivien Priebe, Camilla Mussoni, Denitsa Docheva, Kristina Andelovic, Jürgen Groll, Sahar Salehi, Gregor Lang, Matthias Ryma   +10 more
wiley   +1 more source

In-Use Stability and Functional Efficacy of a Monoclonal Antibody Cocktail (TwinRab™) for Rabies Post-exposure Prophylaxis. [PDF]

Cureus
Kalita P, Kumar S, Bandyopadhyay S, Patel C, Patel M, Soni MS, Patel H, Patel T, Sakhrani N, Dutta T, Mahajan M.   +10 more
europepmc   +1 more source

Advances in Bioprinting to Model Immune‐Mediated Skin Diseases

Advanced Healthcare Materials, EarlyView.
This review explores how 3D bioprinting drives innovation in developing in vitro skin models that mimic immune‐mediated diseases. It highlights current technologies, key applications in studying skin pathologies, and emerging challenges. The review points toward future opportunities for improving disease modeling and advancing therapeutic and cosmetic ...
Andrea Ulloa‐Fernández, Marica Markovic, Julia Fernández‐Pérez, Georg Stary, Aleksandr Ovsianikov   +4 more
wiley   +1 more source

Structure-Guided In-Use Stability Assessment of Monoclonal Antibody Tislelizumab. [PDF]

Pharmaceuticals (Basel)
Rudd DA, Siddiqui G.
europepmc   +1 more source