Results 161 to 170 of about 759,957 (341)

Detection and elimination of non-specific bindings of monoclonal antibodies in t_??_e cell surface marker assay

, 1985
Kozo Takase, Kazue Mizuno, Hiroji Okawa, Junichi Yata   +3 more
openalex   +2 more sources

Use of a monoclonal antibody to determine the mode of transmembrane pore formation by streptolysin O [PDF]

, 1986
F Hugo, J Reichwein, Mardjan Arvand, Susan M. Kramer, Sucharit Bhakdi   +4 more
openalex   +1 more source

GRP78 Nanobody‐Directed Immunotoxin Activates Innate Immunity Through STING Pathway to Synergize Tumor Immunotherapy

Advanced Science, EarlyView.
A GRP78 nanobody‐directed immunotoxin suppresses cancer progression and metastasis by enhancing antitumor immunity via STING pathway activation, offering a pan‐cancer‐targeted approach and immunotherapy combination strategy. Abstract The lack of targetable antigens poses a significant challenge in developing effective cancer‐targeted therapies.
Huifang Wang, Runhua Zhou, Chengchao Xu, Lingyun Dai, Rui Hou, Liuhai Zheng, Chunjin Fu, Guangwei Shi, Jingwei Wang, Yang Li, Jinpeng Cen, Xiaolong Xu, Le Yu, Yilei Li, Jigang Wang, Qingfeng Du, Zhijie Li   +16 more
wiley   +1 more source

Simple recombinant monoclonal antibody production from Escherichia coli. [PDF]

Open Biol
Baker K, Eastwood TA, Garcia E, Lennon C, Mulvihill DP.   +4 more
europepmc   +1 more source

Triton X-114 phase fractionation of an integral membrane surface protein mediating monoclonal antibody killing of Mycoplasma hyorhinis [PDF]

, 1987
Harold Riethman, Mireille Boyer, Kim S. Wise   +2 more
openalex   +1 more source

AKT1 Phosphorylates FDX1 to Promote Cuproptosis Resistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study demonstrates that copper activates the AKT signaling pathway, which inhibits ferredoxin‐1 (FDX1), a key regulator of cuproptosis. AKT1‐mediated FDX1 phosphorylation not only abrogates FDX1‐induced cuproptosis and aerobic respiration but also promotes glycolysis.
Zicheng Sun, Huazhen Xu, Guanming Lu, Ciqiu Yang, Xinya Gao, Jing Zhang, Xin Liu, Yongcheng Chen, Kun Wang, Jianping Guo, Jie Li   +10 more
wiley   +1 more source

Monoclonal antibody generation by controlled immunoglobulin gene rearrangements. [PDF]

Commun Biol
Murayama A, Matsui S, Abe T, Kanemaki MT, Kurosawa K, Hirota K, Ohta K, Seo H.   +7 more
europepmc   +1 more source

PCSK9 Promotes the Malignancy of Triple‐negative Breast Cancer Cells by Reducing Cholesterol Levels at the Plasma Membrane to Activate EGFR and HER3

Advanced Science, EarlyView.
By decreasing cholesterol and lipid raft levels in the plasma membrane, proprotein convertase subtilisin/kexin type 9 (PCSK9) boosts human epidermal growth factor receptor 1 and 3 (EGFR and HER3) activation, driving tumor growth and metastasis in triple‐negative breast cancer (TNBC).
Tianhong Li, Renfei Wu, Kathy Qian Luo
wiley   +1 more source

Assessing concentration in the monoclonal antibody innovation market: A patent-based study. [PDF]

PLoS One
Motta-Santos AS, Ribeiro LC, Gow J, Alam K, de Souza Noronha KVM, Andrade MV.   +5 more
europepmc   +1 more source

Efficient generation in vitro, from human peripheral blood cells, of monoclonal Epstein-Barr virus transformants producing specific antibody to a variety of antigens without prior deliberate immunization.

, 1983
Larry Winger, Caroline M. Winger, Padma Shastry, Amanda J. Russell, Michael Longenecker   +4 more
openalex   +1 more source