Single-cell epigenetic and transcriptomic states across the continuum of monoclonal B cell lymphocytosis to chronic lymphocytic leukemia [PDF]
Genome BiologyBackground Chronic lymphocytic leukemia (CLL) develops from physiologic B cells through low- and high-count monoclonal B cell lymphocytosis (LC-/HC-MBL).
Anja C. Rathgeber +11 more
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Case report: ‘Atypical Richter transformation from CLL-type monoclonal B-cell lymphocytosis into Burkitt lymphoma in a treatment naïve patient’ [PDF]
Frontiers in OncologyBackgroundRichter transformation refers to the progression of an initially slow-growing small lymphocytic lymphoma/chronic lymphocytic leukemia (SLL/CLL) into an aggressive lymphoma, typically diffuse large B-cell lymphoma (DLBCL) or Hodgkin lymphoma ...
Annaïse J. Jauch +8 more
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CHIP amplifies the risk of lymphoid malignancies in individuals with monoclonal B-cell lymphocytosis (MBL) [PDF]
Blood Cancer JournalMonoclonal B-cell lymphocytosis (MBL) and clonal hematopoiesis of indeterminate potential (CHIP) are prevalent clonal precursors associated with increased risk of lymphoid malignancies.
Nicholas J. Boddicker +20 more
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Mosaic chromosomal alterations (mCAs) in individuals with monoclonal B-cell lymphocytosis (MBL) [PDF]
Blood Cancer JournalMBL is a precursor condition to chronic lymphocytic leukemia (CLL), characterized by monoclonal B-cells in blood. Mosaic chromosomal alterations (mCAs) are a form of clonal hematopoiesis that include gains, losses, and copy-neutral loss-of-heterozygosity
Aswin Sekar +18 more
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Understanding Monoclonal B Cell Lymphocytosis: An Interplay of Genetic and Microenvironmental Factors [PDF]
Frontiers in Oncology, 2021 The term monoclonal B-cell lymphocytosis (MBL) describes the presence of a clonal B cell population with a count of less than 5 × 109/L and no symptoms or signs of disease.
Chrysi Galigalidou +10 more
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The risk of coronavirus disease 2019 (COVID-19) among individuals with monoclonal B cell lymphocytosis [PDF]
Blood Cancer Journal, 2022 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the underlying cause of coronavirus disease 2019 (COVID-19), is a novel coronavirus that has caused a global pandemic, with more than 84 million cases and over 1 million deaths reported in the
Sameer A. Parikh +13 more
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CD20+ T cells in monoclonal B cell lymphocytosis and chronic lymphocytic leukemia: frequency, phenotype and association with disease progression [PDF]
Frontiers in OncologyIntroductionIn monoclonal B cell lymphocytosis (MBL) and chronic lymphocytic leukemia (CLL), the expansion of malignant B cells disrupts the normal homeostasis and interactions between B cells and T cells, leading to immune dysregulation.
Cristiana Rodrigues +46 more
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Monoclonal B‐Cell Lymphocytosis: The Silent Clone the Haematologists Should Not Neglect [PDF]
Hematol OncolMonoclonal B‐cell lymphocytosis (MBL) is a hematologic condition defined by the presence of a small clonal B‐cell population in the peripheral blood, without clinical or laboratory evidence of lymphoproliferative disorders.
Andrea Serafin +6 more
semanticscholar +2 more sources
State of the art biology, progression, and clinical management of monoclonal B-cell lymphocytosis (MBL): consensus report from the Intercepting Blood Cancers Workshop Committee [PDF]
Blood Cancer JIn March 2023 and 2024, a panel of international experts convened at the first and second Intercepting Blood Cancers (IBC) Workshops, with the aim of better appreciating the diagnostic challenges, pathophysiology, and potential therapeutic interventions ...
C. Ryan +22 more
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Necrotic Ulcers from Occlusive Vasculopathy Associated with Monoclonal B Cell Lymphocytosis [PDF]
Acta Dermato-Venereologica, 2023 is missing (Shot communication)
Delwyn Zhi Jie Lim +3 more
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