Results 21 to 30 of about 16,555,945 (165)

The humoral immune response to high-dose influenza vaccine in persons with monoclonal B-cell lymphocytosis (MBL) and chronic lymphocytic leukemia (CLL) [PDF]

Vaccine, 2021
Background: Limited data are available regarding the immunogenicity of high-dose influenza vaccine among persons with chronic lymphocytic leukemia (CLL) and monoclonal B cell lymphocytosis (MBL).
J. Whitaker, S. Parikh, T. Shanafelt, N. Kay, R. Kennedy, D. Grill, Krista M. Goergen, T. Call, Saad S Kendarian, W. Ding, G. Poland   +10 more
semanticscholar   +2 more sources

Polygenic Risk Score and Risk of Monoclonal B-cell Lymphocytosis in Caucasians and Risk of Chronic Lymphocytic Leukemia (CLL) in African Americans [PDF]

Leukemia, 2021
Monoclonal B-cell lymphocytosis (MBL) is a precursor to CLL. Other than age, sex, and CLL family-history, little is known about factors associated with MBL risk.
G. Kleinstern, J. Weinberg, S. Parikh, E. Braggio, S. Achenbach, Dennis P. Robinson, Aaron D. Norman, K. Rabe, N. Boddicker, C. Vachon, C. Lesnick, T. Call, D. Brander, L. Rassenti, T. Kipps, J. Olson, J. Cerhan, N. Kay, R. Furman, C. Hanson, T. Shanafelt, S. Slager   +21 more
semanticscholar   +2 more sources

Paraneoplastic progressive encephalomyelitis with rigidity and myoclonus associated with monoclonal B-cell lymphocytosis in the setting of longstanding methotrexate use: case report [PDF]

Front Immunol
Progressive encephalomyelitis with rigidity and myoclonus (PERM) is a rare but debilitating disease within the stiff person syndrome (SPS) spectrum characterised by muscle rigidity, spasms, myoclonus, dysautonomia, and brainstem dysfunction.
F. Jia, M. Amin, Gi Tae Kwon, Amir Mousapasandi, Pei Dai, Jed Kitson, Adrian G. Selim, Jerome Ip   +7 more
semanticscholar   +2 more sources

Warthin’s Tumor Involved by Monoclonal B-Cell Lymphocytosis: A Case Report [PDF]

Cureus
Warthin’s tumor is a benign salivary gland neoplasm characterized by oncocytic epithelium and lymphoid stroma. We describe the incidental discovery of a CD5-positive monoclonal B-cell population within a classic Warthin’s tumor of the parotid gland in a ...
Alexie E. Kindy, Ziang Wang, Robin Gautam, R. Bennett, Zi-Jian Wang   +4 more
semanticscholar   +2 more sources

Host virus and pneumococcus-specific immune responses in high-count monoclonal B-cell lymphocytosis and chronic lymphocytic leukemia: implications for disease progression [PDF]

Haematologica, 2017
Patients diagnosed with chronic lymphocytic leukemia (CLL) display a high incidence of infections due to an associated immunodeficiency that includes hypogammaglobulinemia.
Ignacio Criado, Santiago Muñoz-Criado, Arancha Rodríguez-Caballero, Wendy G. Nieto, Alfonso Romero, Paulino Fernández-Navarro, Miguel Alcoceba, Teresa Contreras, Marcos González, Alberto Orfao, Julia Almeida   +10 more
doaj   +2 more sources

Risk of incident melanoma among individuals with low count monoclonal B-cell lymphocytosis (MBL) [PDF]

J Clin Oncol
PURPOSE Chronic lymphocytic leukemia (CLL)–phenotype monoclonal B-cell lymphocytosis (MBL) is a premalignant condition that is roughly 500-fold more common than CLL. It is unknown whether the two-fold increased risk of developing melanoma associated with
Bryan A. Vallejo, A. Ansari, S. Parikh, S. Achenbach, K. Rabe, Aaron D. Norman, J. Olson, Neil E. Kay, E. Braggio, C. Hanson, Celine M. Vachon, J. Cerhan, Cristian L Baum, T. Shanafelt, S. Slager   +14 more
semanticscholar   +2 more sources

Comparison of microRNA expression in high-count monoclonal B-cell lymphocytosis and Binet A chronic lymphocytic leukemia

Revista Brasileira de Hematologia e Hemoterapia
Background Evidence suggests that monoclonal B-cell lymphocytosis precedes all chronic lymphocytic leukemia cases, although the molecular mechanisms responsible for disease progression are not understood.
Felipe Magalhães Furtado, Priscila Santos Scheucher, Bárbara Amélia Santana, Dalila Lucíola Zanette, Rodrigo do Tocantins Calado, Eduardo Magalhães Rego, Daniel Mazza Matos, Roberto Passetto Falcão   +7 more
doaj   +2 more sources

Paroxysmal Cold Hemoglobinuria Associated With Monoclonal B-Cell Lymphocytosis in an Elderly Patient: A Report of a Rare Case [PDF]

Cureus
We report the case of an 86-year-old male with chronic anemia who presented with indirect hyperbilirubinemia, undetectable haptoglobin, and reticulocytosis. The peripheral smear showed no schistocytes.
Summiya Nasim, Matthew Bartock
semanticscholar   +2 more sources

Tumor mutational load is prognostic for progression to therapy among high-count monoclonal B-cell lymphocytosis [PDF]

Blood Adv
Key Points • Tumor mutational load is a strong prognostic factor for progression to therapy among individuals with HCMBL, independent of CLL-IPI.• Accounting for both CLL-IPI and tumor mutational load, we identified individuals with HCMBL who have a ...
G. Kleinstern, N. Boddicker, D. R. O'Brien, C. Allmer, K. Rabe, Aaron D. Norman, Rosalie Griffin, Hui-Huang Yan, Tao Ma, T. Call, L. Bruins, S. Brown, Cecilia Bonolo de Campos, C. Hanson, J. Leis, Wei Ding, Celine M. Vachon, Neil E. Kay, Christopher C. Oakes, A. Parker, D. Brander, J. Weinberg, Richard R. Furman, T. Shanafelt, J. Cerhan, S. Parikh, E. Braggio, S. Slager   +27 more
semanticscholar   +2 more sources

A Single‐Center Retrospective Study of the Investigation of Monoclonal B‐Cell Lymphocytosis (MBL) and Chronic Lymphocytic Leukemia (CLL) in Southwestern Ontario: Are We Over‐Investigating? [PDF]

Int J Lab Hematol
Monoclonal B‐cell lymphocytosis (MBL) is a common cause of lymphocytosis in older individuals. Although cytogenetic/molecular testing is usually reserved for patients requiring treatment, recent studies suggest that early testing may have a prognostic ...
Ortenc Hoxha, M. Lad, Ben D Hedley, I. Chin-Yee, Cyrus C. Hsia, B. Chin-Yee   +5 more
semanticscholar   +2 more sources