Results 11 to 20 of about 16,555,945 (165)

Low-count monoclonal B-cell lymphocytosis persists after seven years of follow up and is associated with a poorer outcome [PDF]

Haematologica, 2018
Low-count monoclonal B-cell lymphocytosis is defined by the presence of very low numbers of circulating clonal B cells, usually phenotypically similar to chronic lymphocytic leukemia cells, whose biological and clinical significance remains elusive ...
Ignacio Criado, Arancha Rodríguez-Caballero, M. Laura Gutiérrez, Carlos E. Pedreira, Miguel Alcoceba, Wendy Nieto, Cristina Teodosio, Paloma Bárcena, Alfonso Romero, Paulino Fernández-Navarro, Marcos González, Julia Almeida, Alberto Orfao, The Primary Health Care Group of Salamanca for the Study of MBL   +13 more
doaj   +7 more sources

Renal complications in chronic lymphocytic leukemia and monoclonal B-cell lymphocytosis: the Mayo Clinic experience [PDF]

Haematologica, 2015
While the renal complications of plasma cell dyscrasia have been well-described, most information in patients with chronic lymphocytic leukemia and monoclonal B-cell lymphocytosis is derived from case reports. This is a retrospective analysis of patients
Paolo Strati, Samih H. Nasr, Nelson Leung, Curtis A. Hanson, Kari G. Chaffee, Susan M. Schwager, Sara J. Achenbach, Timothy G. Call, Sameer A. Parikh, Wei Ding, Neil E. Kay, Tait D. Shanafelt   +11 more
doaj   +3 more sources

Monoclonal B-cell lymphocytosis in individuals from sporadic (non-familial) chronic lymphocytic leukemia families persists over time, but does not progress to chronic B-cell lymphoproliferative diseases [PDF]

Revista Brasileira de Hematologia e Hemoterapia, 2015
BACKGROUND: Monoclonal B-cell lymphocytosis is classified as 'high-count or clinical' monoclonal B-cell lymphocytosis and 'low-count or population' monoclonal B-cell lymphocytosis.
Daniel Mazza Matos, Felipe Magalhães Furtado, Roberto Passetto Falcão   +2 more
doaj   +4 more sources

Highly similar genomic landscapes in monoclonal B-cell lymphocytosis and ultra-stable chronic lymphocytic leukemia with low frequency of driver mutations [PDF]

Haematologica, 2018
Despite the recent discovery of recurrent driver mutations in chronic lymphocytic leukemia, the genetic factors involved in disease onset remain largely unknown.
Andreas Agathangelidis, Viktor Ljungström, Lydia Scarfò, Claudia Fazi, Maria Gounari, Tatjana Pandzic, Lesley-Ann Sutton, Kostas Stamatopoulos, Giovanni Tonon, Richard Rosenquist, Paolo Ghia   +10 more
doaj   +3 more sources

Concurrent B Cell Acute Lymphoblastic Lymphoma/Leukemia and Monoclonal B Cell Lymphocytosis: A Case Report with Extensive Molecular Analysis [PDF]

Case Reports in Hematology, 2022
Although acute lymphoblastic leukemia (ALL) and monoclonal B cell lymphocytosis (MBL) are common neoplasia, a simultaneous presentation is very unusual.
Maryam Mehdipour Dalivand, Parastou Tizro, Julie Partain, Anita Aggarwal, Jack Lichy, Francisco Mot Ara, Victor E. Nava   +6 more
doaj   +3 more sources

Monoclonal B-cell lymphocytosis (MBL): biology, natural history and clinical management

Leukemia, 2010
Chronic lymphocytic leukemia (CLL) and the other low-grade non-Hodgkin lymphomas are among the most common lymphoid malignancies. Recent studies suggest that more than 4% of the general population over age 40 harbor a population of clonal B cells with ...
Ola Landgren, Andy C Rawstron, Paolo Ghia   +2 more
exaly   +3 more sources

Monoclonal B-cell lymphocytosis with renal involvement

Saudi Journal of Kidney Diseases and Transplantation, 2018
We report the case of a 70-year-old man with no relevant past medical history who presented with acute kidney injury. Kidney biopsy showed diffuse interstitial infiltration with typical chronic lymphocytic leukemia (CLL) phenotype B-cells.
Yao-Ko Wen
doaj   +2 more sources

Genomic instability and genetic heterogeneity in aging: insights from clonal hematopoiesis (CHIP), monoclonal gammopathy (MGUS), and monoclonal B-cell lymphocytosis (MBL) [PDF]

Geroscience
Aging is a multifaceted process characterized by a gradual decline in physiological function and increased susceptibility to a range of chronic diseases.
Attila Kállai, Z. Ungvari, M. Fekete, Andrea B. Maier, G. Mikala, H. Andrikovics, Andrea Lehoczki   +6 more
semanticscholar   +2 more sources

The CLL International Prognostic Index predicts outcomes in monoclonal B-cell lymphocytosis and Rai 0 CLL

Blood, 2021
In this month’s CME article, Parikh and colleagues describe a minor adjustment to the CLL-International Prognostic Index (IPI), adding the lymphocyte count to test its utility in patients with either monoclonal B-cell lymphocytosis or very early–stage ...
S. Parikh, K. Rabe, N. Kay, T. Call, W. Ding, J. Leis, S. Kenderian, Eli Muchtar, Yucai Wang, A. Koehler, S. Schwager, C. Lesnick, G. Kleinstern, D. V. Van Dyke, C. Hanson, E. Braggio, S. Slager, T. Shanafelt   +17 more
semanticscholar   +2 more sources

Humoral and cellular immune responses to recombinant herpes zoster vaccine in patients with chronic lymphocytic leukemia and monoclonal B cell lymphocytosis [PDF]

Am J Hematol, 2021
Monoclonal B‐cell lymphocytosis (MBL) and chronic lymphocytic leukemia (CLL) are clonal B‐cell disorders associated with an increased risk of infections and impaired vaccination responses. We investigated the immunogenicity of recombinant zoster vaccine (
Eli Muchtar, A. Koehler, Michael J. Johnson, K. Rabe, W. Ding, T. Call, J. Leis, Saad S. Kenderian, S. Hayman, Yucai Wang, P. Hampel, M. Holets, H. Darby, S. Slager, N. Kay, Cong-Rong Miao, J. Canniff, J. Whitaker, M. Levin, D. Schmid, Richard B. Kennedy, A. Weinberg, S. Parikh   +22 more
semanticscholar   +2 more sources