Results 81 to 90 of about 16,334 (217)
Anogenital Papular Mucinosis in Chronic Anal Fissures: A Review of a Reactive Mucinous Pattern
ABSTRACT Background Anogenital papular mucinosis (APM) is a rare localized cutaneous mucinosis characterized by dermal mucin deposition presenting as flesh‐colored papules in the anogenital region. Its rarity and clinical resemblance to common infectious and inflammatory dermatoses contribute to frequent misdiagnosis.
Douglas Jaxon Vadner +5 more
wiley +1 more source
Where Is the ‘Oma’ in Multiple Myeloma? Origins and Limitations of some Myeloma‐Related Terminology
ABSTRACT Background Multiple myeloma, often simply called ‘myeloma’, is a clonal plasma cell malignancy that constitutes about one‐tenth of all cancers managed by haematologists. Although the disease was first clearly described in the first half of the 19th century, it was only called multiple myeloma several decades later.
Jecko Thachil, David P. Steensma
wiley +1 more source
ABSTRACT Introduction Light chain (AL) amyloidosis and transthyretin amyloid cardiomyopathy (ATTR‐CM) are the most common types of cardiac amyloidosis. Despite similar manifestations, prognosis and treatments are distinct, emphasizing the importance of accurate and timely diagnosis. This retrospective cohort study assessed real‐world diagnostic workups
Muhamed Baljevic +7 more
wiley +1 more source
Clinical Features and Therapeutic Outcomes in Pyoderma Gangrenosum: A Prospective Cohort Study
ABSTRACT Background Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis highly associated with systemic comorbidities. Accurate diagnosis and treatment remain challenging due to its rarity and clinical mimickers. Objectives To evaluate demographic, clinical features and treatment outcomes in patients referred with suspected PG at a tertiary ...
David Croitoru +13 more
wiley +1 more source
Therapeutic Options for IgA Pemphigus in Patients Refractory to Dapsone
ABSTRACT IgA pemphigus is a rare autoimmune blistering disorder with limited therapeutic guidance available due to its rarity and complex presentation. This comprehensive analysis evaluates the therapeutic outcomes of 67 published patients, emphasising the significant role of dapsone as the first‐line treatment.
Lorenz Frasheri +2 more
wiley +1 more source
ABSTRACT Monoclonal immunoglobulin deposition disease (MIDD) is a plasma cell disorder where immunoglobulin light‐ and/or heavy‐chains accumulate in various organs. Hepatic involvement can be challenging to diagnose, as manifestations are protean and Congo red staining is negative.
Bella L. Liu +5 more
wiley +1 more source
CHD4 plays an essential role as an epigenetic regulator in the pathogenesis of multiple myeloma. The chromatin remodeling protein initially resolves G‐quadruplex (G4) secondary structures within the c‐Myc promoter region, thereby enhancing chromatin accessibility and promoting transcriptional activation.
Pinggang Ding +10 more
wiley +1 more source
The incidence of secondary monoclonal gammopathy of undetermined significance is limited in patients with multiple myeloma post chimeric antigen receptor T-cell therapy.
Nilesh M. Kalariya +3 more
doaj +1 more source
ABSTRACT Rituximab is an anti‐CD20 monoclonal antibody used in autoimmune diseases, including glomerular diseases. The FCGR2A (rs1801274) and FCGR3A (rs396991) variants have been suggested to affect rituximab efficacy; this study evaluates their impact on rituximab efficacy in glomerular diseases.
María Larrosa‐García +10 more
wiley +1 more source

