Results 81 to 90 of about 16,334 (217)

Anogenital Papular Mucinosis in Chronic Anal Fissures: A Review of a Reactive Mucinous Pattern

open access: yesDermatological Reviews, Volume 7, Issue 3, June 2026.
ABSTRACT Background Anogenital papular mucinosis (APM) is a rare localized cutaneous mucinosis characterized by dermal mucin deposition presenting as flesh‐colored papules in the anogenital region. Its rarity and clinical resemblance to common infectious and inflammatory dermatoses contribute to frequent misdiagnosis.
Douglas Jaxon Vadner   +5 more
wiley   +1 more source

Where Is the ‘Oma’ in Multiple Myeloma? Origins and Limitations of some Myeloma‐Related Terminology

open access: yeseJHaem, Volume 7, Issue 3, June 2026.
ABSTRACT Background Multiple myeloma, often simply called ‘myeloma’, is a clonal plasma cell malignancy that constitutes about one‐tenth of all cancers managed by haematologists. Although the disease was first clearly described in the first half of the 19th century, it was only called multiple myeloma several decades later.
Jecko Thachil, David P. Steensma
wiley   +1 more source

Real‐World Diagnostic Workup of Patients Suspected for Light Chain Amyloidosis and Wild‐Type Transthyretin Amyloid Cardiomyopathy: A Retrospective Cohort Study Using US Electronic Health Records

open access: yeseJHaem, Volume 7, Issue 3, June 2026.
ABSTRACT Introduction Light chain (AL) amyloidosis and transthyretin amyloid cardiomyopathy (ATTR‐CM) are the most common types of cardiac amyloidosis. Despite similar manifestations, prognosis and treatments are distinct, emphasizing the importance of accurate and timely diagnosis. This retrospective cohort study assessed real‐world diagnostic workups
Muhamed Baljevic   +7 more
wiley   +1 more source

Clinical Features and Therapeutic Outcomes in Pyoderma Gangrenosum: A Prospective Cohort Study

open access: yesJEADV Clinical Practice, Volume 5, Issue 2, Page 495-501, June 2026.
ABSTRACT Background Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis highly associated with systemic comorbidities. Accurate diagnosis and treatment remain challenging due to its rarity and clinical mimickers. Objectives To evaluate demographic, clinical features and treatment outcomes in patients referred with suspected PG at a tertiary ...
David Croitoru   +13 more
wiley   +1 more source

Therapeutic Options for IgA Pemphigus in Patients Refractory to Dapsone

open access: yesJEADV Clinical Practice, Volume 5, Issue 2, Page 415-424, June 2026.
ABSTRACT IgA pemphigus is a rare autoimmune blistering disorder with limited therapeutic guidance available due to its rarity and complex presentation. This comprehensive analysis evaluates the therapeutic outcomes of 67 published patients, emphasising the significant role of dapsone as the first‐line treatment.
Lorenz Frasheri   +2 more
wiley   +1 more source

Hepatic Monoclonal Light‐ and Heavy‐Chain Deposition Disease Presenting as Noncirrhotic Portal Hypertension With Ascites

open access: yesLiver International Communications, Volume 7, Issue 2, June 2026.
ABSTRACT Monoclonal immunoglobulin deposition disease (MIDD) is a plasma cell disorder where immunoglobulin light‐ and/or heavy‐chains accumulate in various organs. Hepatic involvement can be challenging to diagnose, as manifestations are protean and Congo red staining is negative.
Bella L. Liu   +5 more
wiley   +1 more source

CHD4 Orchestrates Chromatin Remodeling to Activate the c‐Myc Signaling Pathway in Cancer Pathogenesis

open access: yesMedComm – Oncology, Volume 5, Issue 2, June 2026.
CHD4 plays an essential role as an epigenetic regulator in the pathogenesis of multiple myeloma. The chromatin remodeling protein initially resolves G‐quadruplex (G4) secondary structures within the c‐Myc promoter region, thereby enhancing chromatin accessibility and promoting transcriptional activation.
Pinggang Ding   +10 more
wiley   +1 more source

Secondary monoclonal gammopathy of unknown significance with isotype switching after CAR T-cell therapy for multiple myeloma: A case report

open access: yesCurrent Problems in Cancer: Case Reports
The incidence of secondary monoclonal gammopathy of undetermined significance is limited in patients with multiple myeloma post chimeric antigen receptor T-cell therapy.
Nilesh M. Kalariya   +3 more
doaj   +1 more source

Prognostic value of MYD88/CXCR4 mutation allele fraction in Waldenström macroglobulinemia using a multiplex ddPCR assay

open access: yes
HemaSphere, Volume 10, Issue 6, June 2026.
Eleni Thanou   +18 more
wiley   +1 more source

Impact of FCGR2A and FCGR3A Gene Variants on the Response to Rituximab in Patients With Glomerular Diseases

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT Rituximab is an anti‐CD20 monoclonal antibody used in autoimmune diseases, including glomerular diseases. The FCGR2A (rs1801274) and FCGR3A (rs396991) variants have been suggested to affect rituximab efficacy; this study evaluates their impact on rituximab efficacy in glomerular diseases.
María Larrosa‐García   +10 more
wiley   +1 more source

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