Results 71 to 80 of about 10,254 (215)
Objective Monoclonal gammopathy of undetermined significance (MGUS) is the asymptomatic precursor of multiple myeloma (MM). Lytic bone lesions and fractures are hallmarks of MM and although there are no lytic lesions in MGUS, it has also been associated ...
Turesson, Ingemar +21 more
core +1 more source
ABSTRACT Cutaneous crystal‐storing histiocytosis (CSH) is an extremely rare histopathologic finding of histiocytes accumulating crystals of immunoglobulin or paraproteins, often associated with lymphoplasmacytic malignancies. It commonly presents in a wide age range of both female and male adults with a history of a lymphoproliferative disorder ...
Ashton Arlen +3 more
wiley +1 more source
Monoclonal gammopathy of undetermined significance (MGUS) is one of the most prevalent premalignant conditions associated with a risk of malignant transformation to multiple myeloma (MM) or other forms of lymphoproliferative disorders with risk of progression of approximately 1% per year.
Sandecká, Viera +6 more
openaire +1 more source
Understanding Monoclonal Gammopathy of Undetermined Significance
Monoclonal gammopathy of undetermined significance (MGUS) is a premalignant plasma cell disorder characterized by serum monoclonal protein (M-protein) levels less than 3.0 g/dL, less than 10% plasma cells in the bone marrow, and absence of end-organ ...
Winkel, Scott, MSPH, MHS, PA-C
core +1 more source
Type-I Cryoglobulinaemia Associated to Monoclonal Gammapathy of Undetermined Significance
Cryoglobulins are immunoglobulins that undergo reversible precipitation at cold temperatures. Monoclonal type-I cryoglobulinaemia is the least frequent and is associated to hematological diseases such as multiple myeloma, Waldenström’s macroglobulinaemia,
Juan Manuel Duarte +5 more
doaj +1 more source
Immunoglobulin Light Chain Amyloidosis
Waxy, purple nodules and plaques distributed across the distal fingers and thenar eminences. ABSTRACT Symmetric, purpuric hand nodules and macroglossia prompted skin biopsy revealing immunoglobulin light chain amyloidosis, leading to the diagnosis of multiple myeloma.
Justin Lyon +3 more
wiley +1 more source
Management of Patients With Hepatitis C Virus, Monoclonal Gammopathy of Undetermined Significance, and Multiple Myeloma [PDF]
Background and Aim: The vast majority of the 2.7 million individuals in the United States who are currently infected with hepatitis C virus (HCV) were born between 1945 and 1965.
David Del Bello +20 more
core +1 more source
Polycythemia vera is a type of myeloproliferative neoplasm characterized by panmyelosis, with a predominant increase in erythrocyte mass. In contrast, monoclonal gammopathy of undetermined significance is classified as a premalignant plasma cell disorder
Amane Otoi +4 more
doaj +1 more source
Multiple myeloma remains largely incurable. However, a few patients experience more than 10 years of relapse-free survival and can be considered as operationally cured.
Roberto J. Pessoa de Magalhães +21 more
doaj +1 more source
Where Is the ‘Oma’ in Multiple Myeloma? Origins and Limitations of some Myeloma‐Related Terminology
ABSTRACT Background Multiple myeloma, often simply called ‘myeloma’, is a clonal plasma cell malignancy that constitutes about one‐tenth of all cancers managed by haematologists. Although the disease was first clearly described in the first half of the 19th century, it was only called multiple myeloma several decades later.
Jecko Thachil, David P. Steensma
wiley +1 more source

