Results 41 to 50 of about 101,778 (313)

A Tri‐Culture Heart‐on‐a‐Chip Platform With iPSC‐Derived Cardiac Cells for Predictive Cardiotoxicity Testing

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents the first entirely isogenic heart‐on‐chip, unifying cardiomyocytes, fibroblasts, and endothelial cells from a single iPSC source. The platform reveals a critical biological insight: the endothelium actively shields cardiac tissue from drug‐induced toxicity, challenging the predictive accuracy of conventional, avascular models for ...
Karine Tadevosyan   +12 more
wiley   +1 more source

The United States Love Affair with Maize: A National Security Issue?

open access: yes, 2020
Maize is the most widely grown crop in the United States. The crop has a variety of applications being used for food, fuel, and in some industries. Maize is heavily integrated into the fabric of billions of lives across the world.
Kelly, Jared
core  

Integration of freshwater prawn culture with rice farming in Kuttanad, India [PDF]

open access: yes, 2002
The integration of paddy cultivation with prawn/fish culture can become a viable alternative to effectively utilize the vast area of derelict polders (embanked coastal flood plains) in Kuttanad, India.
Kurup, B.M., Ranjeet, K.
core  

Cultivar diversity as a means of ecologically intensifying dry matter production in a perennial forage stand [PDF]

open access: yes, 2014
The relationship between genotypic diversity and productivity has not been adequately explored in perennial forage production systems despite strong theoretical and empirical evidence supporting diversity\u27s role in ecosystem functioning in other ...
Pollnac, F. W.   +2 more
core   +2 more sources

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

open access: yesAdvanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu   +4 more
wiley   +1 more source

Benefits of host genetic diversity for resistance to infection depend on parasite diversity [PDF]

open access: yes, 2010
Host populations with high genetic diversity are predicted to have lower levels of infection prevalence. This theory assumes that host genetic diversity results in variation in susceptibility and that parasites exhibit variation in infectivity. Empirical
Ebert, D., Ganz, H.
core   +1 more source

Oxygen Supply of Islets of Langerhans by Photosynthetically Active Microalgae in Bioprinted Co‐Cultures Maintains Their Function in a Hypoxic Environment

open access: yesAdvanced Healthcare Materials, EarlyView.
This study developed a bioprinted co‐culture system embedding rat pancreatic islets and Scenedesmus sp. microalgae spatially defined in close vicinity. Red light was found optimal to ensure microalgal photosynthesis while maintaining islet viability and functionality. A tailored co‐culture medium supported both cell types.
Finn Dani   +7 more
wiley   +1 more source

Nutrient supply to reed canary grass as a bioenergy crop [PDF]

open access: yes, 2012
Production of renewable energy from herbaceous crops on agricultural land is of great interest since fossil fuels need to be replaced with sustainable energy sources. Reed canary grass (RCG), Phalaris arundinacea L.
Lindvall, Eva
core  

A Physiological Microfluidic Blood–Brain‐Barrier Model for In Vitro Study of Nanoparticle Trafficking and Accumulation

open access: yesAdvanced Healthcare Materials, EarlyView.
A human microfluidic blood‐brain barrier (mBBB) model enables spatially resolved comparison of nanoparticle trafficking. Extracellular vesicles (EVs), liposomes, and nanoplastics exhibit distinct transport and disruption behaviors, revealing that membrane composition and uptake pathways govern BBB interaction.
Bryan B. Nguyen   +9 more
wiley   +1 more source

Soil management in Lepidium meyenii (maca) monoculture: trends and challenges for small farmers around Lake Chinchaycocha in the Andean highlands of Junin (Peru)

open access: yesFrontiers in Soil Science
IntroductionMonoculture is a significant concern due to its negative impact on soil quality, resource productivity, and agricultural sustainability, particularly in vulnerable communities.
Richard Solórzano-Acosta   +12 more
doaj   +1 more source

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