Results 221 to 230 of about 400,128 (308)

Biological importance of cytomegalovirus infection in health and disease : Profound effects of infection on monocyte and smooth muscle cell function

, 2005
Sara Gredmark
openalex  

Potent and Long‐Lasting Immunogenicity Generated by LNP‐mRNA gE Antigen Against Varicella Zoster Virus via an AI‐Assisted Pipeline

Advanced Science, EarlyView.
This study designs a novel mRNA‐LNP vaccine targeting VZV glycoprotein E (gE) for herpes zoster via an AI‐assisted pipeline. Validated in mice and rhesus macaques, the mRNA‐LNP vaccine shows strong humoral and cellular immune responses, with CD4+ T‐cell responses more effective and durable than Shingrix, offering a promising prophylactic option ...
Kai Dong, Fang Liu, Dawei Wang, Yanfen Li, Man Zhang, Yuting Zhou, Gengshen Song   +6 more
wiley   +1 more source

Chemoattractive potential of stem cells from apical papilla in peripheral blood monocytes: an in vitro study. [PDF]

Braz Dent J
Santos AGD, Santos LM, Rahhal JG, Sloniak M, Villar CC, Nogueira FN, Sipert CR.   +6 more
europepmc   +1 more source

The Disordered Region of ASXL1 Acts as an Auto‐Regulator Through Condensation

Advanced Science, EarlyView.
ASXL1's long IDR encodes an electrostatic “basic platform + acidic brake” that autoregulates condensation. Truncation at a clinical hotspot lifts this brake, forming condensates that retarget BRD2, remodel local chromatin accessibility, and impair neutrophil maturation.
Xiao Fang, Qiwei Li, Wenqing Zhang
wiley   +1 more source

Monocyte/macrophage-mediated trained immunity in disease prevention and immunotherapy. [PDF]

Bioact Mater
Zhang X, Wang X, Xu M, Yuan J, Liu Y.
europepmc   +1 more source

Neutralizing Staphylococcus aureus PAMPs that Trigger Cytokine Release from THP-1 Monocytes

Neda Heydarian, Maya Ferrell, Ayesha S. Nair, Chase C. Roedl, Zongkai Peng, Tra D. Nguyen, William R. Best, Karen L. Wozniak, Charles V. Rice   +8 more
openalex   +1 more source

A Biomarker‐Driven Ovary–Endometrium Organ‐on‐a‐Chip Mimicking 3D Multicellular Complexity and Menstrual Cyclicity for Predicting Reproductive Toxicity

Advanced Science, EarlyView.
We present a dual‐organ, biomarker‐integrated ovaryendometrium organ‐on‐a‐chip that recapitulates 3D tissue complexity, menstrual cycle dynamics, and hormonal crosstalk. This platform enables real‐time, cell‐typespecific fluorescent readouts of reproductive toxicity using ANGPTL4 and SERPINB2 as early‐response reporters.
Soo‐Rim Kim, Eun‐kyung Min, Choon‐Mi Lee, Chan Hum Park, Byung‐Chul Oh, YunJae Jung, In‐Sun Hong   +6 more
wiley   +1 more source

IGFBP4 is a Metric for Primary Biliary Cholangitis and Attenuates Biliary Epithelial Cell Injury. [PDF]

Liver Int
Zhou X, Shao S, Yang D, Cheng Z, Tanaka T, Leung PSC, Tsuneyama K, Ansari AA, Ridgway WM, Invernizzi P, Bowlus CL, Gershwin ME, Zhang W.   +12 more
europepmc   +1 more source

Postoperative Stress Accelerates Atherosclerosis Through Inflammatory Remodeling of the HDL Proteome and Impaired Reverse Cholesterol Transport

Advanced Science, EarlyView.
The study shows that noncardiac surgical inflammation rapidly disrupts HDL function and cholesterol efflux in mice and human patients. Impaired reverse cholesterol transport after surgery drives rapid lipid accumulation, NETosis, and apoptosis within atherosclerotic plaques.
Dominique M. Boucher, Victoria Lorant, Valerie Rochon, Abigail Carter, Cameron Stotts, My‐Anh Nguyen, Thomas Laval, Christina Emerton, Nathan Joyce, Nysa Vinayak, Marlena Scaffidi, David Cook, Katey J. Rayner, Rebecca C. Auer, Scott M. Gordon, Mireille I. Ouimet   +15 more
wiley   +1 more source

Association of Inflammation-Based Ratios with Endothelial Dysfunction Markers and Clinical Parameters in Limited Cutaneous Systemic Sclerosis. [PDF]

J Clin Med
Schweiger L, Meinitzer A, Strohmaier H, Moazedi-Fürst F, Nemecz V, Kurzmann-Gütl K, Brodmann M, Hafner F, Jud P.   +8 more
europepmc   +1 more source