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Thiazolidinedione inhibits the production of monocyte chemoattractant protein-1 in cytokine-treated human vascular endothelial cells [PDF]
FEBS Letters, 1999 The chemokine monocyte chemoattractant protein-1 is a potent chemoattractant for monocytes. Monocyte chemoattractant protein-1 is produced by vascular endothelial cells during inflammatory diseases such as atherosclerosis.
Koji Murao, H Imachi, J Takahara
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Monocyte chemoattractant protein-1 and hypertension: An overview
Hipertensión y Riesgo Vascular, 2022The association between hypertension and cardiovascular disease (CVD) has been increasingly studied through early inflammatory biomarkers. The monocyte chemoattractant protein-1 (MCP-1) is the main chemokine implicated in the inflammatory endothelial process, attracting monocytes and macrophages to the atherosclerotic plaque.We reviewed the main ...
A, Cortez, E, Muxfeldt
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Human Pathology, 1993
The infiltration of blood monocytes into the subendothelial space is thought to be one of the most important pathologic events in early atherogenesis. To examine the mechanism of monocyte migration in early atherosclerotic lesions we investigated immunohistochemically the production of monocyte chemoattractant protein-1 (MCP-1) in various ...
Teizo Yoshimura, E J Leonard, M Takeya
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The infiltration of blood monocytes into the subendothelial space is thought to be one of the most important pathologic events in early atherogenesis. To examine the mechanism of monocyte migration in early atherosclerotic lesions we investigated immunohistochemically the production of monocyte chemoattractant protein-1 (MCP-1) in various ...
Teizo Yoshimura, E J Leonard, M Takeya
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Monocyte chemoattractant protein-1 and the kidney
Current Opinion in Nephrology and Hypertension, 2016Recently, initial studies have been carried out in patients using monocyte chemoattractant protein-1 (MCP-1) inhibitors. This review summarizes the known function of MCP-1 in regulating monocytes during inflammation and its role in inflammatory disease of the kidney.MCP-1 is one of the first chemokines described and plays an important role in renal ...
Hermann, Haller +3 more
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Role of Monocyte Chemoattractant Protein-1 and its Receptor,CCR-2, in the Pathogenesis of Bleomycin-Induced Scleroderma [PDF]
Journal of Investigative Dermatology, 2003 Systemic sclerosis is a connective tissue disease characterized by excessive deposition of extracellular matrix in the skin as well as various internal organs.
Toshiyuki Yamamoto
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The role of monocyte chemoattractant protein-1 in biliary atresia
Journal of Pediatric Surgery, 2006The aim of this study was to explain the role of monocyte chemoattractant protein-1 (MCP-1) in biliary atresia (BA).Concentrations of serum MCP-1 and collagen type IV were measured in 38 patients with BA by using commercially available kits. MCP-1 was also assessed in liver biopsy specimens by using immunohistochemistry.
Atsuyuki Yamataka +2 more
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Expression of monocyte chemoattractant protein-1 in meningioma
Journal of Neurosurgery, 1995✓ Monocyte chemoattractant protein-1 (MCP-1), purified from glioma cell line (U-105MG) culture fluid, attracts monocytes but not neutrophils. Macrophage accumulation is one of the pathological features of meningioma. To investigate the mechanism of macrophage infiltration into meningioma, the expression and localization of MCP-1 in 16 cases of ...
K, Sato +4 more
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The regulation and importance of monocyte chemoattractant protein-1
Current Opinion in Hematology, 2018Purpose of review Monocyte chemoattractant protein (MCP)-1, a chemokine regulating monocyte chemotaxis and T-lymphocyte differentiation by binding to the CC chemokine receptor 2 (CCR2), plays a crucial role in the pathogenesis of inflammatory diseases, atherosclerosis and cancer.
Bianconi, Vanessa +3 more
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CCL2 (monocyte chemoattractant protein-1) and cancer
Seminars in Cancer Biology, 2004Genetic analyses of cancer in humans indicate that chemokines and their receptors are unlikely to play direct roles in pathogenesis. However, these molecules have pleiotropic effects that impact on cancer pathobiology in animal models, and there is evidence that they may do the same in humans. Given their protean properties, chemokines could have tumor-
Ilaria, Conti, Barrett J, Rollins
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