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Production of monocyte chemoattractant protein‐1 in amyotrophic lateral sclerosis
Muscle & Nerve, 2005AbstractThe presence of activated microglia in the spinal cord of amyotrophic lateral sclerosis (ALS) patients is usually accompanied by inflammatory biochemical changes, but these are largely unexplored. Monocyte chemoattractant protein‐1 (MCP‐1) is critical for recruitment of inflammatory cells of monocytic lineage after inflammation or injury to the
P. L. Baron +10 more
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Monocyte Chemoattractant Protein-1 in the Intervertebral Disc
Spine, 1998Monocyte chemoattractant protein-1 was investigated in an experimental rat model using immunohistochemistry.To ascertain the precise mechanism of macrophage recruitment in the early phase of disc resorption.In previous studies, many investigators reported that disc herniation was resorbed by monocytic phagocytosis.
T, Kikuchi +4 more
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Dobutamine Inhibits Monocyte Chemoattractant Protein-1 Production and Chemotaxis in Human Monocytes
Anesthesia & Analgesia, 2003It has been reported that, in patients with acute myocardial infarction or congestive heart failure, monocyte chemoattractant protein-1 (MCP-1) plays an important role in the development of inflammatory responses and that the level of MCP-1 is correlated with the severity of the disease.
Chi-Yuan, Li +6 more
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Monocyte Chemoattractant Protein-1(MCP-1)
1995Abstract MCP-1 was first described as lymphocyte-derived chemotactic factor (LDCF). Other names are tumour cell-derived chemotactic factor (TDCF), glioma-derived monocyte chemotactic factor (GDCF), smooth muscle cell-derived chemotactic factor (SMC-CF), monocyte chemotactic and activating factor (MCAF). The gene of the mouse homologue
T Yoshimura, E J Leonard
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Cysteinyl leukotrienes induce monocyte chemoattractant protein 1 in human monocytes/macrophages
Clinical & Experimental Allergy, 2005SummaryBackground Monocytes/macrophages have a cysteinyl leukotriene 1 (CysLT1) receptor, but its function is poorly understood.Objective To elucidate the biological function of the CysLT1 receptor of human monocytes/macrophages.Methods We examined the production of TNF‐α, IL‐1β, IL‐2, IL‐4, IL‐6, IL‐8, IL‐10, monocyte chemoattractant
T, Ichiyama +5 more
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Biochemical and Biophysical Research Communications, 2002
Two isoforms of human CCR2, the receptor for monocyte chemoattractant protein-1 (MCP-1), have been identified but their relative expression in monocytes and contribution to inflammatory responses mediated by MCP-1 remain uncertain. All available information on CCR2 expression is based on mRNA data because isoform-specific antibodies were not available ...
Seiya, Tanaka +2 more
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Two isoforms of human CCR2, the receptor for monocyte chemoattractant protein-1 (MCP-1), have been identified but their relative expression in monocytes and contribution to inflammatory responses mediated by MCP-1 remain uncertain. All available information on CCR2 expression is based on mRNA data because isoform-specific antibodies were not available ...
Seiya, Tanaka +2 more
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Molecular Medicine Today, 1996
The appearance of specific types of leukocytes in inflammatory infiltrates may be governed by cell-specific chemoattractants called chemokines. In particular, monocyte chemoattractant protein 1 (MCP-1) has been implicated in diseases characterized by monocyte-rich infiltrates, including atherosclerosis, rheumatoid arthritis and multiple sclerosis ...
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The appearance of specific types of leukocytes in inflammatory infiltrates may be governed by cell-specific chemoattractants called chemokines. In particular, monocyte chemoattractant protein 1 (MCP-1) has been implicated in diseases characterized by monocyte-rich infiltrates, including atherosclerosis, rheumatoid arthritis and multiple sclerosis ...
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