Results 251 to 260 of about 32,111,831 (291)
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Human Monocyte Chemoattractant Protein-1 (MCP-1)
Immunology Today, 1990During the past three years great advances have been made in the chemistry and biology of chemoattractants for human leukocytes. Two chemoattractant cytokines have been isolated, sequenced and cloned, each with distinctive leukocyte attractant specificity.
E J, Leonard, T, Yoshimura
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The Journal of Immunology, 1995
Abstract Monocyte chemoattractant protein (MCP)-2 and -3 are recently identified members of the Cys-Cys chemokine family and are highly homologous to MCP-1. MCP-1, MCP-2, and MCP-3 are potent chemoattractants for monocytes, basophils, and T lymphocytes. In this study, we have examined potential interactions of MCP-2 and MCP-3 with the
C, Franci +4 more
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Abstract Monocyte chemoattractant protein (MCP)-2 and -3 are recently identified members of the Cys-Cys chemokine family and are highly homologous to MCP-1. MCP-1, MCP-2, and MCP-3 are potent chemoattractants for monocytes, basophils, and T lymphocytes. In this study, we have examined potential interactions of MCP-2 and MCP-3 with the
C, Franci +4 more
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Monocyte chemoattractant protein 1 in luteolysis
Reviews of Reproduction, 2000Monocyte chemoattractant protein 1 (MCP-1) is a member of the chemokine family of cytokines which are involved in leukocyte physiology and trafficking. Interest in the role of inflammatory cells and their cytokine products in luteolysis has been increasing and there is mounting evidence demonstrating that MCP-1 is involved in luteolysis.
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Characterization of the Bovine Monocyte Chemoattractant Protein-1 Gene
Biochemical and Biophysical Research Communications, 1994Bovine monocyte chemoattractant protein-1 (bovine MCP-1) cDNA has recently been characterized and shown to be highly expressed in bovine seminal vesicles. In an attempt to isolate the MCP-1 gene, we screened a bovine genomic lambda EMBL-3 library with an MCP-1 specific probe pH42. A positive clone lambda MCP1 was subjected to restriction analysis and a
Wempe, F., Kuhlmann, J., Scheit, K.
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Polymorphism of monocyte chemoattractant protein 1 in Crohn's disease
International Journal of Colorectal Disease, 2003The chemokine MCP-1 is thought to be important for the recruitment of mononuclear cells and the maintenance of inflammation in inflammatory bowel disease. We investigated whether MCP-1 protein expression is correlated with the degree of mucosal inflammation in patients with Crohn's disease. Furthermore, we studied whether a functional single nucleotide
Hans, Herfarth +6 more
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Urinary monocyte chemoattractant protein-1 in renal disease
Clinica Chimica Acta, 2011Monocyte chemoattractant protein-1 (MCP-1/CCL2) has a critical role in the development of various renal diseases. Data from disease specific experimental animal models and clinical studies confirm that MCP-1 plays an important part in the pathogenesis of renal diseases.
Min Jeong, Kim, Frederick W K, Tam
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Curcumin as a natural regulator of monocyte chemoattractant protein-1
Cytokine & Growth Factor Reviews, 2017Monocyte chemoattractant/chemotactic protein-1 (MCP-1), a member of the CC chemokine family, is one of the key chemokines that regulate migration and tissue infiltration of monocytes/macrophages. Its role in the pathophysiology of several inflammatory diseases has been widely recognized, thus making MCP-1 a possible target for anti-inflammatory ...
Karimian, MS +3 more
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Very low-density lipoprotein stimulates the expression of monocyte chemoattractant protein-1 in mesangial cells [PDF]
Kidney International, 2000 Very low-density lipoprotein stimulates the expression of monocyte chemoattractant protein-1 in mesangial cells.BackgroundElevated plasma levels of very low-density lipoprotein (VLDL) are associated with an increased risk for focal glomerulosclerosis ...
Yaw Siow, Karmin O, Edward G Lynn
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Expression of monocyte chemoattractant protein-1 in vascular tissue
Cytokine, 1995We investigated monocyte chemoattractant protein-1 (MCP-1) mRNA expression in rat vascular smooth muscle cells (VSMC) and in human atherosclerotic arteries to test the involvement of MCP-1 in the pathogenesis of atherosclerosis. In Northern blot analysis, MCP-1 mRNA expression was not observed in unstimulated cultured rat vascular smooth muscle cells ...
Y, Seino +6 more
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Targeting monocyte chemoattractant protein-1 signalling in disease
Expert Opinion on Therapeutic Targets, 2003Monocyte chemoattractant protein-1 (MCP-1) has been implicated in many inflammatory and autoimmune diseases. The G-protein-coupled receptor CCR-2B is probably the most important MCP-1 receptor in vivo, and loss of MCP-1 effector function alone is sufficient to impair monocytic trafficking in inflammation models.
Janet, Dawson +3 more
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