Monocyte chemoattractant protein-1/CCL2 produced by stromal cells promotes lung metastasis of 4T1 murine breast cancer cells. [PDF]
PLoS ONE, 2013 MCP-1/CCL2 plays an important role in the initiation and progression of cancer. Since tumor cells produce MCP-1, they are considered to be the main source of this chemokine.
Teizo Yoshimura +9 more
doaj +13 more sources
The Chemokine MIG is Associated with an Increased Risk of COVID-19 Mortality in Mexican Patients [PDF]
Iranian Journal of Immunology, 2022 Background: Coronavirus disease 2019 (COVID-19) is an emergent viral disease in which the host inflammatory response modulates the clinical outcome. Severe outcomes are associated with an exacerbation of inflammation in which chemokines play an important
Luis Ochoa-Ramirez +10 more
doaj +1 more source
Computational and Structural Biotechnology Journal, 2022 Bundle sheath (BS) cells exhibit dramatically structural differences and functional variations at physiological, biochemical and epigenetic levels as compared to mesophyll (M) cells in maize.
Shentong Tao, Wenli Zhang
doaj +1 more source
Orthopaedic Surgery, 2022 Objective To investigate the changes in proinflammatory cytokines and chemokines, namely, C‐C motif ligand (CCL) 2 and CCL7, in postmenopausal osteoporosis (PMOP) and to develop a new drug, bindarit (Bnd), for PMOP in an ovariectomized (OVX) mouse model.
Shi‐guo Yuan +6 more
doaj +1 more source
Denervated Schwann cells attract macrophages by secretion of leukemia inhibitory factor (LIF) and monocyte chemoattractant protein-1 in a process regulated by interleukin-6 and LIF [PDF]
, 2002 Injury to peripheral nerves results in the infiltration of immune cells, which remove axonal- and myelin-derived material. Schwann cells could play a key role in this process by regulating macrophage infiltration.
Jessen, KR +3 more
core +2 more sources
Rack1 regulates pro-inflammatory cytokines by NF-κB in diabetic nephropathy
Open Medicine, 2022 Diabetic nephropathy (DN) is one of the chronic microvascular diseases of diabetes. Studies revealed that inflammation is involved in the development of DN. However, its mechanisms are not fully clear. Here, we screened DN-related mRNAs by RNA sequencing
Wu Keqian +8 more
doaj +1 more source
The miR-145 rs353291 C allele increases susceptibility to atherosclerosis
Frontiers in Bioscience-Landmark, 2020 Atherosclerosis (AS) is one of the leading causes of death, with variable frequencies in different populations. To this end, we examined whether AS is associated with the miR-145 rs353291 polymorphism and specific rs353291 alleles.
Yu Lv +5 more
doaj +1 more source
Effect of high glucose concentration on the synthesis of monocyte chemoattractant protein-1 in human peritoneal mesothelial cells: Involvement of protein kinase C [PDF]
, 2001 Human peritoneal mesothelial cells (HMC) contribute to the activation and control of inflammatory processes in the peritoneum by their potential to produce various inflammatory mediators.
Haslinger, Bettina +4 more
core +1 more source
Data in Brief, 2016 The data presented in this article are related to the research article entitled “Elevated levels of monocyte chemoattractant protein-1 in the aqueous humor after phacoemulsification” (M. Kawai, T. Inoue, M. Inatani, N. Tsuboi, K. Shobayashi, A. Matsukawa,
Motofumi Kawai +3 more
doaj +1 more source
trans-Chalcone protects male rats against high-fat emulsion-induced pancreatic injury by inhibiting TNF-α and MCP-1 expression [PDF]
مجله پزشکی دانشگاه علوم پزشکی تبریز, 2023 Background. High-fat diet (HFD) intake is linked to ectopic fat deposition in the pancreas. It also causes pancreatic inflammatory lesions. trans-Chalcone is a simple chalcone with protective effects against HFD-induced metabolic disorders.
Elham Karimi-Sales +1 more
doaj +1 more source