Results 291 to 300 of about 130,905 (336)

Role of Monocyte Chemoattractant Protein-1 and its Receptor,CCR-2, in the Pathogenesis of Bleomycin-Induced Scleroderma

open access: yesJournal of Investigative Dermatology, 2003
Systemic sclerosis is a connective tissue disease characterized by excessive deposition of extracellular matrix in the skin as well as various internal organs.
Toshiyuki Yamamoto
exaly   +2 more sources
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Expression of monocyte chemoattractant protein-1 in meningioma

Journal of Neurosurgery, 1995
✓ Monocyte chemoattractant protein-1 (MCP-1), purified from glioma cell line (U-105MG) culture fluid, attracts monocytes but not neutrophils. Macrophage accumulation is one of the pathological features of meningioma. To investigate the mechanism of macrophage infiltration into meningioma, the expression and localization of MCP-1 in 16 cases of ...
K, Sato   +4 more
openaire   +2 more sources

CCL2 (monocyte chemoattractant protein-1) and cancer

Seminars in Cancer Biology, 2004
Genetic analyses of cancer in humans indicate that chemokines and their receptors are unlikely to play direct roles in pathogenesis. However, these molecules have pleiotropic effects that impact on cancer pathobiology in animal models, and there is evidence that they may do the same in humans. Given their protean properties, chemokines could have tumor-
Ilaria, Conti, Barrett J, Rollins
openaire   +2 more sources

Monocyte chemoattractant protein 1 in luteolysis

Reviews of Reproduction, 2000
Monocyte chemoattractant protein 1 (MCP-1) is a member of the chemokine family of cytokines which are involved in leukocyte physiology and trafficking. Interest in the role of inflammatory cells and their cytokine products in luteolysis has been increasing and there is mounting evidence demonstrating that MCP-1 is involved in luteolysis.
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Monocyte chemoattractant protein-3, but not monocyte chemoattractant protein-2, is a functional ligand of the human monocyte chemoattractant protein-1 receptor.

The Journal of Immunology, 1995
Abstract Monocyte chemoattractant protein (MCP)-2 and -3 are recently identified members of the Cys-Cys chemokine family and are highly homologous to MCP-1. MCP-1, MCP-2, and MCP-3 are potent chemoattractants for monocytes, basophils, and T lymphocytes. In this study, we have examined potential interactions of MCP-2 and MCP-3 with the
C, Franci   +4 more
openaire   +2 more sources

Urinary monocyte chemoattractant protein-1 in renal disease

Clinica Chimica Acta, 2011
Monocyte chemoattractant protein-1 (MCP-1/CCL2) has a critical role in the development of various renal diseases. Data from disease specific experimental animal models and clinical studies confirm that MCP-1 plays an important part in the pathogenesis of renal diseases.
Min Jeong, Kim, Frederick W K, Tam
openaire   +2 more sources

A brief look at the role of monocyte chemoattractant protein-1 (CCL2) in the pathophysiology of psoriasis.

Cytokine, 2017
Psoriasis (PsO) is a chronic skin disorder resulting from the imbalanced interactionbetween infiltrating immune cells and keratinocytes. These immune cells, including monocytes, are able to mediate the immune responses in inflamed skin lesions ...
S. Behfar   +3 more
semanticscholar   +1 more source

Characterization of the Bovine Monocyte Chemoattractant Protein-1 Gene

Biochemical and Biophysical Research Communications, 1994
Bovine monocyte chemoattractant protein-1 (bovine MCP-1) cDNA has recently been characterized and shown to be highly expressed in bovine seminal vesicles. In an attempt to isolate the MCP-1 gene, we screened a bovine genomic lambda EMBL-3 library with an MCP-1 specific probe pH42. A positive clone lambda MCP1 was subjected to restriction analysis and a
Wempe, F., Kuhlmann, J., Scheit, K.
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Very low-density lipoprotein stimulates the expression of monocyte chemoattractant protein-1 in mesangial cells

open access: yesKidney International, 2000
Very low-density lipoprotein stimulates the expression of monocyte chemoattractant protein-1 in mesangial cells.BackgroundElevated plasma levels of very low-density lipoprotein (VLDL) are associated with an increased risk for focal glomerulosclerosis ...
Edward G Lynn, Yaw L Siow, Karmin O
exaly   +2 more sources

Polymorphism of monocyte chemoattractant protein 1 in Crohn's disease

International Journal of Colorectal Disease, 2003
The chemokine MCP-1 is thought to be important for the recruitment of mononuclear cells and the maintenance of inflammation in inflammatory bowel disease. We investigated whether MCP-1 protein expression is correlated with the degree of mucosal inflammation in patients with Crohn's disease. Furthermore, we studied whether a functional single nucleotide
Hans, Herfarth   +6 more
openaire   +2 more sources

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