Results 301 to 310 of about 130,905 (336)

Expression of monocyte chemoattractant protein-1 in vascular tissue

Cytokine, 1995
We investigated monocyte chemoattractant protein-1 (MCP-1) mRNA expression in rat vascular smooth muscle cells (VSMC) and in human atherosclerotic arteries to test the involvement of MCP-1 in the pathogenesis of atherosclerosis. In Northern blot analysis, MCP-1 mRNA expression was not observed in unstimulated cultured rat vascular smooth muscle cells ...
Y, Seino, U, Ikeda, M, Takahashi, Y, Hojo, M, Irokawa, T, Kasahara, K, Shimada   +6 more
openaire   +2 more sources

Targeting monocyte chemoattractant protein-1 signalling in disease

Expert Opinion on Therapeutic Targets, 2003
Monocyte chemoattractant protein-1 (MCP-1) has been implicated in many inflammatory and autoimmune diseases. The G-protein-coupled receptor CCR-2B is probably the most important MCP-1 receptor in vivo, and loss of MCP-1 effector function alone is sufficient to impair monocytic trafficking in inflammation models.
Janet, Dawson, Wolfgang, Miltz, Anis K, Mir, Christoph, Wiessner   +3 more
openaire   +2 more sources

Monocyte Chemoattractant Protein-1 in the Intervertebral Disc

Spine, 1998
Monocyte chemoattractant protein-1 was investigated in an experimental rat model using immunohistochemistry.To ascertain the precise mechanism of macrophage recruitment in the early phase of disc resorption.In previous studies, many investigators reported that disc herniation was resorbed by monocytic phagocytosis.
T, Kikuchi, T, Nakamura, T, Ikeda, H, Ogata, K, Takagi   +4 more
openaire   +2 more sources

Cysteinyl leukotrienes induce monocyte chemoattractant protein 1 in human monocytes/macrophages

Clinical & Experimental Allergy, 2005
SummaryBackground Monocytes/macrophages have a cysteinyl leukotriene 1 (CysLT1) receptor, but its function is poorly understood.Objective To elucidate the biological function of the CysLT1 receptor of human monocytes/macrophages.Methods We examined the production of TNF‐α, IL‐1β, IL‐2, IL‐4, IL‐6, IL‐8, IL‐10, monocyte chemoattractant
T, Ichiyama, M, Hasegawa, Y, Ueno, H, Makata, T, Matsubara, S, Furukawa   +5 more
openaire   +2 more sources

Dobutamine Inhibits Monocyte Chemoattractant Protein-1 Production and Chemotaxis in Human Monocytes

Anesthesia & Analgesia, 2003
It has been reported that, in patients with acute myocardial infarction or congestive heart failure, monocyte chemoattractant protein-1 (MCP-1) plays an important role in the development of inflammatory responses and that the level of MCP-1 is correlated with the severity of the disease.
Chi-Yuan, Li, Chien-Sung, Tsai, Sheau-Huei, Chueh, Ping-Ching, Hsu, Jia-Yi, Wang, Chih-Shung, Wong, Shung-Tai, Ho   +6 more
openaire   +2 more sources

Differential Expression of the Isoforms for the Monocyte Chemoattractant Protein-1 Receptor, CCR2, in Monocytes

Biochemical and Biophysical Research Communications, 2002
Two isoforms of human CCR2, the receptor for monocyte chemoattractant protein-1 (MCP-1), have been identified but their relative expression in monocytes and contribution to inflammatory responses mediated by MCP-1 remain uncertain. All available information on CCR2 expression is based on mRNA data because isoform-specific antibodies were not available ...
Seiya, Tanaka, Simone R, Green, Oswald, Quehenberger   +2 more
openaire   +2 more sources

Monocyte Chemoattractant Protein-1(MCP-1)

1995
Abstract MCP-1 was first described as lymphocyte-derived chemotactic factor (LDCF). Other names are tumour cell-derived chemotactic factor (TDCF), glioma-derived monocyte chemotactic factor (GDCF), smooth muscle cell-derived chemotactic factor (SMC-CF), monocyte chemotactic and activating factor (MCAF). The gene of the mouse homologue
T Yoshimura, E J Leonard
openaire   +1 more source

Monocyte chemoattractant protein-1 levels in patients with glomerular disease

American Journal of Kidney Diseases, 1996
Chemokines such as monocyte chemoattractant protein-1 (MCP-1) and interleukin-8 have been implicated in recruiting leukocytes to the glomerulus during immune renal injury. To detect the expression of MCP-1 in human glomerular disease, we measured urinary MCP-1 levels in patients with a variety of glomerulopathies. These data demonstrated that MCP-1 was
B H, Rovin, N, Doe, L C, Tan
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Monocyte chemoattractant protein 1: a potential regulator of monocyte recruitment in inflammatory disease

Molecular Medicine Today, 1996
The appearance of specific types of leukocytes in inflammatory infiltrates may be governed by cell-specific chemoattractants called chemokines. In particular, monocyte chemoattractant protein 1 (MCP-1) has been implicated in diseases characterized by monocyte-rich infiltrates, including atherosclerosis, rheumatoid arthritis and multiple sclerosis ...
openaire   +2 more sources

Monocyte Chemoattractant Protein-1

1999
L, Gu, S C, Tseng, B J, Rollins
openaire   +2 more sources