Synthesis of prostaglandins by subpopulations of human peripheral blood monocytes
Prostaglandins, 1979The ability of monocytes/macrophages to regulate various aspects of immunologic responses may in part depend on their release of soluble substances such as prostaglandins. Using quantitative gas-liquid chromatography/mass spectrometry, prostaglandin E2 was found to be the major prostaglandin synthesized in culture by human peripheral blood monocytes ...
M E, Goldyne, J D, Stobo
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Monocyte subpopulations and cardiovascular risk in chronic kidney disease
Nature Reviews Nephrology, 2012Chronic microinflammation and its cellular hallmark, monocyte activation, contribute substantially to the tremendous burden of cardiovascular disease (CVD) in patients with chronic kidney diseases (CKD). Monocyte heterogeneity is widely acknowledged. Cell-surface expression of CD14 and CD16 defines three functionally and phenotypically distinct subsets
Heine, GH +13 more
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Characteristics of Human Monocyte Subpopulations with the use of Flow Cytometer
1982Human monocytes separated from peripheral blood by Ficoll-Hypaque and by adherence to serum-coated dishes showed a bimodal volume distribution measured with a fluorescence activated cell sorter. The rate of the fluorescein diacetate hydrolysis by small monocytes was lower than that of large ones.
M, Kávai, E, Bodolai, J, Szöllösi
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Heterogeneity of human blood monocytes: the CD14+CD16+ subpopulation
Immunology Today, 1996Abstract Previously, human blood monocyte subpopulations were defined by approaches that required their isolation, such as differential sedimentation or adherence. Therefore, enumeration of subpopulations and their analysis in disease remained difficult.
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Aberrations in Post-trauma Monocyte (Mø) Subpopulation
The Journal of Trauma: Injury, Infection, and Critical Care, 1990Appearance of increased proportions of monocytes bearing the 72kd(FcRI) receptor for IgG correlated to aberrant monocyte (MO) functions, depressed immune functions, and poor clinical outcome. The trauma patients' FcRI+ MO subpopulation produced the majority of their elevated IL-6, TNF alpha, TGF beta, and PGE2.
Miller-Graziano, Carol L. +3 more
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Fc receptors specific for IgE on subpopulations of human lymphocytes and monocytes
Clinical Immunology and Immunopathology, 1980Abstract Fc receptors for IgE (Fcϵ) were detected on human lymphocytes and monocytes by rosette assays employing ox (E0) or chicken (Ec) erythrocytes coated with human myeloma IgE. Peripheral blood from normal donors contained 1.2 ± 0.6% Fc ϵ + lymphocytes and 23 ± 8% Fc ϵ + monocytes. Over 90% of the Fc ϵ +
H L, Spiegelberg, F M, Melewicz
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Identification and characterization of monocyte subpopulations from patients with bronchial asthma
Journal of Allergy and Clinical Immunology, 1995Monocytes are inflammatory cells that accumulate in the airway in asthma. Monocytes constitute a heterogenous cell population in normal subjects. The heterogeneity of monocytes from nine patients with mild asthma and nine normal subjects was studied by means of discontinuous density gradient centrifugation with use of bovine serum albumin.
K, Tomita +6 more
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Characterization of human monocyte subpopulations by flow cytometry.
Immunology, 1982Human monocytes separated from peripheral blood by Ficoll-Hypaque and by adherence to serum-coated dishes show a bimodal volume distribution measured with a fluorescence-activated cell sorter. In the first peak of size distribution histogram of living mononuclear cells, lymphocytes and small monocytes were characterized by latex phagocytosis and non ...
M, Kávai, E, Bodolay, J, Szöllösi
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A subpopulation of tissue remodeling monocytes stimulates revascularization of the ischemic limb
Science Translational MedicineDespite decades of effort aimed at developing clinically effective cell therapies, including mixed population mononuclear cells, to revascularize the ischemic limb, there remains a paucity of patient-based studies that inform the function and fate of candidate cell types.
Ashish S. Patel +12 more
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A critical view of monocyte subpopulations in human hypercholesterolemia
Atherosclerosis, 2016Latet, Sam C. +5 more
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