Results 31 to 40 of about 176,233 (276)

Differential expression of TNFR1 (CD120a) and TNFR2 (CD120b) on subpopulations of human monocytes

open access: yesJournal of Inflammation, 2012
Background Three subpopulations of monocytes can be distinguished in human blood: classical (CD14++CD16−), intermediate (CD14++CD16+), and nonclassical (CD14+CD16++).
Hijdra Daniëlle   +4 more
doaj   +1 more source

The proliferative human monocyte subpopulation contains osteoclast precursors [PDF]

open access: yesArthritis Research & Therapy, 2009
Abstract Introduction Immediate precursors of bone-resorbing osteoclasts are cells of the monocyte/macrophage lineage. Particularly during clinical conditions showing bone loss, it would appear that osteoclast precursors are mobilized from bone marrow into the circulation prior to entering ...
Lari, R, Kitchener, PD, Hamilton, JA
openaire   +3 more sources

MONOCYTE SUBSETS IN HEALTHY ADULTS AND SEPSIS PATIENTS

open access: yesМедицинская иммунология, 2018
Monocytes play a key role in the development of immune response in bacterial infection, because of their phagocytic, antigen-presenting and secretory functions. There are three subpopulations of monocytes: “classical” CD14+CD16-, “intermediate” CD14+CD16+
A. A. Kalashnikova   +4 more
doaj   +1 more source

Acquired Spontaneous Cytotoxicity of K562 in a Subpopulation of Monocytes

open access: yesImmunobiology, 1985
Human peripheral blood monocytes were placed on a discontinuous density gradient of bovine serum albumin and fractionated into five subpopulations. Cells from each subpopulation were assayed for spontaneous cytotoxic activity against K562 tumor cells. Immediately following fractionation, monocytes were not cytotoxic.
J H, Wyckoff   +3 more
openaire   +2 more sources

CD66b+ monocytes represent a proinflammatory myeloid subpopulation in cancer

open access: yesCancer Immunology, Immunotherapy, 2020
Myeloid-derived suppressor cells (MDSC) populate the peripheral blood and contribute to immune regulation in cancer. However, there is limited knowledge on the myeloid cell types with proinflammatory capacities that may serve as opponents of MDSC.
Utku Horzum   +6 more
openaire   +6 more sources

Profiling of the Three Circulating Monocyte Subpopulations in Human Obesity [PDF]

open access: yesThe Journal of Immunology, 2015
Abstract Three subpopulations of circulating monocytes have been described: CD142+CD16− (classical monocytes [CM]), CD142+CD16+ (intermediate monocytes [IM]), and CD14+CD162+ (nonclassical monocytes [NCM]). We previously showed that obesity is associated with an increased proportion of IM and NCM.
Devevre, Estelle   +5 more
openaire   +3 more sources

The significance of macrophage polarization subtypes for animal models of tissue fibrosis and human fibrotic diseases

open access: yesClinical and Translational Medicine, 2015
The systemic and organ‐specific human fibrotic disorders collectively represent one of the most serious health problems world‐wide causing a large proportion of the total world population mortality.
Peter J Wermuth, Sergio A Jimenez
doaj   +1 more source

TRANSCRIPTOMIC HETEROGENEITY OF MONOCYTES AND ITS CONTRIBUTION TO THE FORMATION OF THE IMMUNE MICROENVIRONMENT IN PROSTATE CANCER

open access: yesМедицинская иммунология, 2019
Our current knowledge of the transcriptomic characteristics of monocyte populations in prostate cancer remains very limited. This is due to the complexity of studying heterogeneous circulating immune cells, which is caused by the variability of cell ...
Yu. V. Sharifyanova   +6 more
doaj   +1 more source

Distinct gene expression patterns for CD14++ and CD16++ monocytes in preeclampsia

open access: yesScientific Reports, 2022
Preeclampsia (PE) is a serious gestational complication affecting the life of a mother and child. The immunophenotype and gene expression profile of isolated blood monocyte subpopulations of pregnant women with PE have not been studied before.
Vishnyakova Polina   +12 more
doaj   +1 more source

Monocyte subset distribution and surface expression of HLA-DR and CD14 in patients after cardiopulmonary resuscitation

open access: yesScientific Reports, 2021
Systemic inflammation is a major feature of the post-cardiac arrest syndrome. The three monocyte subpopulations are thought to play an important role in this inflammatory state because they are endowed with numerous pattern recognition receptors, such as
Alexander Asmussen   +7 more
doaj   +1 more source

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