Results 101 to 110 of about 78,022 (259)

Stress‐Programmed Immune Niches Fuel TNFR2+ Treg Activation and Drive Neoadjuvant Chemotherapy Resistance in Breast Cancer

Advanced Science, EarlyView.
Single‐cell sequencing reveals stress‐programmed immune states driving TNFα–TNFR2–mediated Treg activation and therapy resistance in breast cancer, while targeting this axis restores antitumor immunity. ABSTRACT The tumor microenvironment (TME) harbors diverse immune cell states that shape therapeutic outcomes in breast cancer.
Zhibo Shao, Xuliren Wang, Han Zhu, Ling Yao, Qi Zhang, Zihan Zhai, Xinyi Lv, Xinyuan Xia, Yi Zhang, Xinya Lu, Xinyi Quan, Jiawen Yang, Xinwei Li, Jieyi Dong, Zhi‐ming Shao, Ruoxi Wang, Bingqiu Xiu, Jiong Wu, Sheng Chen   +18 more
wiley   +1 more source

Clinical diagnostic value of methylated SEPT9 combined with NLR, PLR and LMR in colorectal cancer

BMC Gastroenterology
Purpose This study aimed to investigate clinical diagnostic values of mSEPT9 combined with NLR, PLR and LMR in CRC. Methods 329 subjects composed of 120 CRC patients, 105 polyps patients and 104 healthy participants were prospectively recruited ...
Meiyuan Huang, Shuang Deng, Ming Li, Zhenyu Yang, Jiaxing Guo, Yi Deng, Dongliang Chen, Bokang Yan   +7 more
doaj   +1 more source

Ultrasound‐Boosted Liposomal Prodrug Overcomes Age‐Associated Biodistribution Disparity in Pediatric Solid Tumor Therapy

Advanced Science, EarlyView.
The age‐associated disparity of nanocarrier biodistribution limits the nanotherapeutics of childhood solid tumors. This study developed an ultrasound‐activated liposomal prodrug (CSCPTL) to overcome the age‐associated disparity of off‐target distribution.
Danfei Chen, Junjun Xu, Jian Chen, Jue Hu, Xiaobo Xuan, Haifang Cai, Mingdong Yang, Zhuxian Zhou, Guowei Wang   +8 more
wiley   +1 more source

Lymphocyte-to-monocyte ratio in colorectal cancer patients [PDF]

, 2017
Zofia Stasik, E. Wójcik, Urszula Rychlik, J. Tarapacz, Wojciech M. Wysocki, Kanty Kulpa Jan   +5 more
openalex   +1 more source

The Postoperative Lymphocyte to Monocyte Ratio Change Predicts Poor Clinical Outcome in Patients with Esophageal Squamous Cell Carcinoma Undergoing Curative Resection [PDF]

, 2020
Qian Song, Junzhou Wu, Huifen Jiang, Sheng Wang, Shunv Cai   +4 more
openalex   +1 more source

Impact on the survival of neutrophil-lymphocyte ratio, platelet-lymphocyte ratio, and monocyte-lymphocyte ratio on prognosis in children with Hodgkin lymphoma [PDF]

, 2022
Kübra ERTAN, Aysenur Dogru, Buket Kara, Yavuz Köksal   +3 more
openalex   +1 more source

⁠Engineering Adaptive Immunity in 3D: A Patient‐Specific Lymphoid Model Using Stromal Networks and Peripheral Blood Mononuclear Cells

Advanced Science, EarlyView.
This study presents a 3D lymphoid tissue model engineered from adipose‐derived stem cells differentiated into fibroblastic reticular cell–like networks and co‐cultured with immune cells. The engineered system successfully generates antigen‐specific antibodies and cytokine responses, providing a platform for studying adaptive immunity, vaccine efficacy,
Mei ElGindi, Shaza Karaman, Jeremy Teo
wiley   +1 more source

The Role of Admission Glucose and Inflammatory Markers in Histopathological Features of Atherosclerotic Plaques in Carotid and Femoro-Popliteal Arteries

Medicina
Background and Objectives: Atherosclerosis is a chronic inflammatory disease significantly contributing to cardiovascular morbidity and mortality. This study primarily aims to evaluate the role of baseline blood glucose levels and inflammatory markers in
Mircea Cătălin Coșarcă, Suzana Vasilica Șincaru, Emőke Horváth, Daniela Tatiana Sala, Nicolae Alexandru Lazăr, Ludovic Alexandru Szanto, Marius Mihai Harpa, Cosmin Carașcă, Gergő Ráduly, Paula Bândea, Vasile Adrian Mureșan   +10 more
doaj   +1 more source

The relationship between neutrophil/lymphocyte, monocyte//lymphocyte, platelet/lymphocyte ratios and clinical outcomes after ninety days in patients who were diagnosed as having acute ischemic stroke in the emergency room and underwent a mechanical thro

, 2020
Emre Özgen, Murat Güzel, Çetin Kürşad Akpınar, Murat Yücel, Mehmet Demir, Ahmet Baydın   +5 more
openalex   +2 more sources

Absolute Monocyte Count and Lymphocyte-Monocyte Ratio Predict Outcome in Nodular Sclerosis Hodgkin Lymphoma: Evaluation Based on Data From 1450 Patients [PDF]

, 2015
Tamar Tadmor, Alessia Bari, Luigi Marcheselli, Stefano Sacchi, Ariel Aviv, Luca Baldini, Paolo G. Gobbi, Samantha Pozzi, Paola Ferri, Maria Christina Cox, Nicola Cascavilla, Emilio Iannitto, Massimo Federico, Aaron Polliack   +13 more
openalex   +1 more source