Results 141 to 150 of about 613,326 (371)

Isolated Limb Perfusion With Melphalan Triggers Immune Activation in Melanoma Patients

Frontiers in Oncology, 2018
Hyperthermic isolated limb perfusion with melphalan (M-ILP) is a treatment option for melanoma patients with metastases confined to the limbs. This study aimed at defining the role of cellular immunity for the clinical response to M-ILP in melanoma ...
Junko Johansson, Junko Johansson, Roberta Kiffin, Roberta Kiffin, Annica Andersson, Annica Andersson, Per Lindnér, Per Lindnér, Peter L. Naredi, Peter L. Naredi, Roger Olofsson Bagge, Roger Olofsson Bagge, Anna Martner, Anna Martner   +13 more
doaj   +1 more source

STUDIES ON TUBERCLE BACILLUS-MONOCYTE RELATIONSHIP [PDF]

, 1959
Jacob Fong, Dennis Chin, Hajime J. Akiyama, Sanford S. Elberg   +3 more
openalex   +1 more source

Ipilimumab-dependent cell-mediated cytotoxicity of regulatory T cells ex vivo by nonclassical monocytes in melanoma patients

Proceedings of the National Academy of Sciences of the United States of America, 2015
Significance mAbs directed to inhibitory immune receptors represent a very promising class of immunotherapeutics. This study suggests a potential mechanism of action of ipilimumab (a fully human anti–cytotoxic T lymphocyte–associated antigen 4), by which
E. Romano, Monika Kusio-Kobiałka, P. Foukas, Petra Baumgaertner, C. Meyer, P. Ballabeni, O. Michielin, B. Weide, P. Romero, D. Speiser   +9 more
semanticscholar   +1 more source

Time‐Controlled Dual Targeting to Program Systemic and Intercellular Transfer of Therapeutic Effects

Advanced Functional Materials, EarlyView.
Aspirin‐liposomes loaded onto monocytes enable inflammation‐triggered targeting and efficient hand‐over of aspirin to inflamed cells. Monocytes uptake a significant portion of aspirin‐liposomes, prolonging therapeutic action. This approach enhances anti‐inflammatory effects through intercellular transfer, demonstrating a translational strategy for ...
Seung Eun Yu, Jueun Kim, Dae‐Hyun Kim, Sewoom Baek, Suji Park, Seyong Chung, Hak‐Joon Sung   +6 more
wiley   +1 more source

THE DESOXYRIBOSE NUCLEIC ACID (DNA) CONTENT OF HUMAN MONOCYTES AND THEIR DERIVATIVES DURING GIANT CELL FORMATION IN VITRO [PDF]

, 1954
Milton N. Goldstein
openalex   +1 more source

Mesenchymal Stem Cells‐Derived Extracellular Vesicles Mimetics as Osteoinductive Mediators for Bone Healing

Advanced Functional Materials, EarlyView.
Mesenchymal stem cell‐derived nanoghosts (MSC‐NGs) mimic naturally secreted extracellular vesicles (MSC‐EVs) in structure and physicochemical properties but can be synthesized at more translatable yields. As osteogenic agents, MSC‐NGs demonstrate superior outcomes compared to MSC‐EVs.
Antoine Karoichan, Ling Li, Celine J. Agnes, Bettina M. Willie, Maryam Tabrizian   +4 more
wiley   +1 more source

A NEOPLASM OF MONOCYTES OF MICE AND ITS RELATION TO SIMILAR NEOPLASMS OF MAN [PDF]

, 1939
J. Fürth
openalex   +1 more source

Microglia and monocytes synergistically promote the transition from acute to chronic pain after nerve injury

Nature Communications, 2016
Microglia and peripheral monocytes contribute to hypersensitivity in rodent models of neuropathic pain. However, the precise respective function of microglia and peripheral monocytes has not been investigated in these models.
Jiyun Peng, N. Gu, Lijun Zhou, Ukpong B Eyo, Madhuvika Murugan, W. Gan, Long-Jun Wu   +6 more
semanticscholar   +1 more source

Monocytes on the Scar's Edge

Journal of the American College of Cardiology, 2012
During the last decades, intensive investigation has revealed diverse pathophysiological mechanisms of adverse remodeling after myocardial infarction (MI), leading to several therapeutic approaches in clinical care of patients after MI.
Ulrich Hofmann, Stefan Frantz
openaire   +3 more sources

Electric Pulse Regulated MXene Based Nanozymes for Integrative Bioelectricity Immuno‐Cancer Therapy

Advanced Functional Materials, EarlyView.
MXenzyme‐mediated bioelectricity cancer therapy (MXenzyme‐BECT) enhances cancer cell death through irreversible depolarization, ion channel disruption, ROS generation, and immunogenic cell death. Computational simulations reveal the electrical mechanisms by which MXenzyme acts on single cells and support to predict treatment parameters. Next‐generation
Sanghee Lee, Seongchan Kim, Eui‐Sang Yu, Sian Lee, Min Jun Ko, Hyojin Lee, Dong‐Hyun Kim   +6 more
wiley   +1 more source