Results 121 to 130 of about 737,831 (351)

Targeting Post‐Irradiation Thyroid Dysfunction: Electrospun Scaffolds As A Dual‐Action Approach for Antioxidant and Immune Modulation

open access: yesAdvanced Healthcare Materials, EarlyView.
Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim   +5 more
wiley   +1 more source

Evaluation of Clinical and Hematological Inflammatory Profile in Patients Treated for Oral Squamous Cell Carcinoma - A Prospective Cohort Study

open access: yesJournal of Indian Academy of Oral Medicine and Radiology
Background: Cancer treatment can lead to significant morbidities that may persist throughout the life of a patient. Over the past 30 years, there has been no improvement in the percentages of morbidity and mortality of oral squamous cell carcinoma (OSCC)
G Chenchulakshmi   +2 more
doaj   +1 more source

Computational Modeling Meets 3D Bioprinting: Emerging Synergies in Cardiovascular Disease Modeling

open access: yesAdvanced Healthcare Materials, EarlyView.
Emerging advances in three‐dimensional bioprinting and computational modeling are reshaping cardiovascular (CV) research by enabling more realistic, patient‐specific tissue platforms. This review surveys cutting‐edge approaches that merge biomimetic CV constructs with computational simulations to overcome the limitations of traditional models, improve ...
Tanmay Mukherjee   +7 more
wiley   +1 more source

Lipoprotein (a) integrates monocyte-mediated thrombosis and inflammation in atherosclerotic cardiovascular disease

open access: yesJournal of Lipid Research
Elevated levels of lipoprotein (a) [Lp(a)], an apolipoprotein B particle, are causally linked to atherosclerotic cardiovascular disease (ASCVD). Lp(a) is thought to promote ASCVD through multiple mechanisms, including its effects on cholesterol transport,
Robert S. Rosenson   +8 more
doaj   +1 more source

APOPTOSIS INDUCTION IN THE PHAGOCYTIC CELLS BY MYCOBACTERIUM TUBERCULOSISWITH DIFFERENT VIRULENCE [PDF]

open access: yesAnnals of Mechnikov's Institute, 2013
The purpose of this study was to investigate the characteristics of phagocytic cells apoptosis induced in vitro and in vivo by Mycobacterium tuberculosis with different virulence.
Zubriychuk OM, Ilyinskaya IF
doaj  

Muramyl dipeptide mediated immunomodulation on monocyte subsets exerts therapeutic effects in a mouse model of Alzheimer’s disease [PDF]

open access: green, 2020
Adham Fani Malekia   +6 more
openalex   +1 more source

Infusible Extracellular Matrix Biomaterial Enhances Cell‐Specific Pro‐Repair Responses Following Acute Myocardial Infarction

open access: yesAdvanced Healthcare Materials, EarlyView.
We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...
Joshua M. Mesfin   +18 more
wiley   +1 more source

Generation of decellularized human brain tissue for investigating cell-matrix interactions: a proof-of-concept study

open access: yesFrontiers in Bioengineering and Biotechnology
The brain extracellular matrix (ECM) regulates myelin repair and regeneration following a demyelinating event by interacting with neuronal progenitors and immune cells. Therefore, generation and characterization of decellularized human brain tissue (DHBT)
Roemel Jeusep Bueno   +15 more
doaj   +1 more source

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

open access: yesAdvanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami   +4 more
wiley   +1 more source

Transcriptome analysis of classical blood cells reveals downregulation of pro-inflammatory genes in the classical monocytes of long COVID patients

open access: yesFrontiers in Immunology
IntroductionDespite extensive research, the pathogenesis and predispositions underlying long COVID (long-term coronavirus disease 2019) remain poorly understood.MethodsTo address this, we analyzed the immunological landscapes of 44 patients with long ...
Florian Fricke   +10 more
doaj   +1 more source

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