Results 141 to 150 of about 737,831 (351)
Hypoxia is an important hallmark of the tumor microenvironment (TME) in solid tumors and is closely associated with resistance to radiotherapy and a poorer clinical outcome.
Marie-Nicole Theodoraki +12 more
doaj +1 more source
Low tetrahydrobiopterin biosynthetic capacity of human monocytes is caused by exon skipping in 6-pyruvoyl tetrahydropterin synthase [PDF]
Karin Leitner +10 more
openalex +1 more source
IL-1 regulates the IL-23 response to wheat gliadin, the etiologic agent of Celiac Disease [PDF]
Celiac disease (CD) is an autoimmune disease prevalent in ~1% of the general population. CD is unique because both the major genetic (Human Leukocyte Antigen-DQ2/DQ8 alleles) and etiologic factors (dietary glutens) for susceptibility are known.
Alessio Fasano +2 more
core +1 more source
A long‐lived, five‐cell‐type human neurovascular (PENTA) model recreates vascular disorganization and incomplete repair after traumatic brain injury (TBI). By integrating endothelial, glial, neuronal, and immune components within a 3D scaffold, the platform enables time‐resolved analysis of neurovascular remodeling and provides a human‐relevant system ...
Daniel S. Hinrichsen +6 more
wiley +1 more source
Chemotactic and Bactericidal Capacities of Human Newborn Monocytes [PDF]
R Kretschmer +3 more
openalex +1 more source
Design and Synthesis of Peptide‐Polyester Conjugates for Cell‐Mediated Scaffold Degradation
This work describes polycaprolactone (PCL)‐based biomaterials engineered to degrade in response to cell‐secreted proteases. A fast‐degrading peptide (Fast) sequence is integrated into a PCL conjugate backbone to produce a biomaterial that is selectively degraded by multiple cell types compared to its scrambled control (ScrFast).
Korina Vida G. Sinad +7 more
wiley +1 more source
Binding of human C-reactive protein to monocytes: analysis by flow cytometry [PDF]
S P Ballou, Ronald P. Cleveland
openalex +1 more source
ABSTRACT The ascent of novel alternative methods in drug development spotlights the dual needs for improved biological fidelity to in vivo, along with reproducibility, especially in regulatory applications. The need for pre‐clinical models of patient‐derived endometriosis lesions motivates the development of a vascularizable, completely synthetic ...
Lauren Pruett +7 more
wiley +1 more source

