Results 11 to 20 of about 79,932 (302)
Acta bio-medica : Atenei Parmensis, 2019 Hypertension is a significant public health problem. Thirty percent of cases are caused by a single genetic mutation. Hypertension is the predominant and usually the only manifestation in monogenic hypertension Monogenic hypertension may involve mineralcorticoid-dependent or -independent increase in Na+ transport. Diagnosis is based on routine physical
Precone V. +10 more
openaire +5 more sources
Monogenic Diabetes due to ABCC8/KCNJ11 Mutation: Case Study and Review of Literature [PDF]
, 2020 Monogenic diabetes arises due to mutation in a single-gene and is recognized by their striking familial inheritance pattern. This form of diabetes is inherited in an autosomal dominant or recessive fashion, unlike polygenic Type 1 (autoimmune) or type 2 ...
Wei, C, Bano, G, Karunakaran, V
core +3 more sources
Monogenic Causes of Strokes [PDF]
Genes, 2021 Strokes are the main cause of death and long-term disability worldwide. A stroke is a heterogeneous multi-factorial condition, caused by a combination of environmental and genetic factors. Monogenic disorders account for about 1% to 5% of all stroke cases.
Justyna Chojdak-Łukasiewicz +2 more
openaire +3 more sources
Starting with the differential: Representation of monogenic functions by polynomials of non-monogenic variables [PDF]
, 2023 This paper deals with different power series expansions of generalized holomorphic (monogenic) functions in the setting of Clifford Analysis. Our main concern are generalized Appell polynomials as a special class of monogenic polynomials which have been ...
Cação, I. +3 more
core +2 more sources
Monogenic Cyclotomic compositions [PDF]
Kodai Mathematical Journal, 2021 Let $m$ and $n$ be positive integers, and let $p$ be a prime. Let $T(x)=Φ_{p^m}\left(Φ_{2^n}(x)\right)$, where $Φ_k(x)$ is the cyclotomic polynomial of index $k$. In this article, we prove that $T(x)$ is irreducible over $\mathbb Q$ and that \[\left\{1,θ,θ^2,\ldots,θ^{2^{n-1}p^{m-1}(p-1)-1}\right\}\] is a basis for the ring of integers of $\mathbb Q(θ)$
Harrington, Joshua, Jones, Lenny
openaire +3 more sources
Annual Review of Immunology, 2012 Monogenic autoimmune syndromes provide a rare yet powerful glimpse into the fundamental mechanisms of immunologic tolerance. Such syndromes reveal not only the contribution of an individual breakpoint in tolerance but also patterns in the pathogenesis of autoimmunity.
Mickie H, Cheng, Mark S, Anderson
openaire +2 more sources
The scheme of monogenic generators II: local monogenicity and twists
Research in Number Theory, 2023 30 pages, comments welcome; some results strengthened over last revision.
Sarah Arpin +3 more
openaire +4 more sources
Monogenic Inflammatory Bowel Disease: It's Never Too Late to Make a Diagnosis
Frontiers in Immunology, 2020 Background: More than 50 different monogenic disorders have been identified as directly causing inflammatory bowel diseases, typically manifesting in the first years of life.
Iddo Vardi +36 more
doaj +1 more source
Isolated benign persistent proteinuria with novel association of CUBN (cubilin) variants
Clinical Case Reports, 2023 Key Clinical Message We present two siblings with persistent proteinuria and normal kidney function, each carrying the same compound heterozygous variants in the CUBN gene. The CUBN‐related phenotype appears to be dependent upon both variant type and the
Vivian Shi +5 more
doaj +1 more source
Frontiers in Immunology, 2022 Most B cells produced in the bone marrow have some level of autoreactivity. Despite efforts of central tolerance to eliminate these cells, many escape to periphery, where in healthy individuals, they are rendered functionally non-responsive to ...
Isaac T. W. Harley +7 more
doaj +1 more source