Results 1 to 10 of about 112,263 (200)
Evolutionary Applications, 2023 Malaria control uses insecticides to kill Anopheles mosquitoes. Recent successes in malaria control are threatened by increasing levels of insecticide resistance (IR), requiring insecticide resistance management (IRM) strategies to mitigate this problem.
Neil Philip Hobbs +2 more
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Frontiers in Genetics, 2022 Background: Monogenic familial hypercholesterolaemia (FH) is an autosomal dominant disorder characterised by elevated low-density lipoprotein cholesterol (LDL-C) concentrations due to monogenic mutations in LDLR, APOB, PCSK9, and APOE.
Jasmine Gratton +8 more
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Identification of Novel Loci and Candidate Genes for Cucumber Downy Mildew Resistance Using GWAS
Plants, 2020 Downy mildew (DM) is one of the most serious diseases in cucumber. Multiple quantitative trait loci (QTLs) for DM resistance have been detected in a limited number of cucumber accessions.
Xiaoping Liu +6 more
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Obesities, 2022 Obesity, classified as an epidemic by the WHO, is a disease that continues to grow worldwide. Obesity results from abnormal or excessive accumulation of fat and usually leads to the development of other associated diseases, such as type 2 diabetes ...
Tânia Martins +7 more
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Frontiers in Genetics, 2021 There is hope that genomic information will assist prediction, treatment, and understanding of Alzheimer’s disease (AD). Here, using exome data from ∼10,000 individuals, we explore machine learning neural network (NN) methods to estimate the impact of ...
Bradley Monk +7 more
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Frontiers in Plant Science, 2022 Heavy metals are an increasing problem due to contamination from human sources that and can enter the food chain by being taken up by plants. Understanding the genetic basis of accumulation and tolerance in plants is important for reducing the uptake of ...
Timothy Paape +5 more
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Phenome-wide and genome-wide analyses of quality of life in schizophrenia
BJPsych Open, 2021 Background Schizophrenia negatively affects quality of life (QoL). A handful of variables from small studies have been reported to influence QoL in patients with schizophrenia, but a study comprehensively dissecting the genetic and non-genetic ...
Raha Pazoki +6 more
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Clinical and Experimental Hypertension, 2019 Angiotensin I converting enzyme (ACE) gene is one of the most-studied candidate genes related to essential hypertension (EH). Pulse pressure (PP) may reflect vascular stiffness, especially in patients with EH, and has been used to predict EH.
Ningning Wang +8 more
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Clinical and Experimental Hypertension, 2018 Angiotensin converting enzyme (ACE) gene, as a strong candidate gene for essential hypertension(EH), has been extensively studied. In this study, we carried out a population-based case-control study to explore whether ACE gene I/D and A2350G ...
Feifei Sun +5 more
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Agronomy, 2020 Weed management is a challenge for farmers worldwide, and the problem is exacerbated by the spread of weed herbicide resistance. Simulation models that combine population dynamics and genetics are valuable tools for predicting the impact of competing ...
Christoph von Redwitz, Friederike de Mol
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