Results 21 to 30 of about 112,263 (200)

Balanced Combinations of Polygenes [PDF]

Nature, 1964
SCHARLOO1 has discussed certain of our results2 in relation to what he purports is a summary of Mather's ideas concerning polygenic balance. We feel it necessary to criticize his communication inasmuch as it seems to us misleading in at least four ways.
J M, THODAY, J B, GIBSON
openaire   +4 more sources

Common polygenic risk for autism spectrum disorder (ASD) is associated with cognitive ability in the general population [PDF]

, 2015
Cognitive impairment is common among individuals diagnosed with autism spectrum disorder (ASD) and attention-deficit hyperactivity disorder (ADHD). It has been suggested that some aspects of intelligence are preserved or even superior in people with ASD ...
Starr, J., D J Porteous, Hocking, L J, Porteous, D. J., Thomson, P A; id_orcid, Hocking, L. J., Davies, G., Medland, S E, S E Medland, Hocking, L.J., Wright, M.J., Porteous, D J, J Starr, Lupton, M. K., Hall, L.S., Montgomery, G W, Clarke, T.-K., Medland, S.E., Pattie, A., Martin, N.G., Liewald, D.C., Padmanabhan, S., Deary, I J, C Hayward, Smith, B.H., Hall, L S, Smith, B. H.; id_orcid, Fernandez-Pujals, A. M., Wright, M J, G W Montgomery, Hansell, N K, D C Liewald, Hall, L. S., N K Hansell, Wright, M. J., N G Martin, Hayward, C., S Cox, Liewald, D. C., Cox, S., Starr, J, Montgomery, G. W., I J Deary, Thomson, P. A., B H Smith, Deary, I. J., Fernandez-Pujals, A M, Lupton, M K, Hayward, C; id_orcid, M K Lupton, Davies, Gail, P A Thomson, Clarke, T-K, A M McIntosh, Hansell, N. K., Hansell, N.K., MacIntyre, D J; id_orcid, MacIntyre, D. J., L J Hocking, Smith, B. H., Cox, S, Fernandez-Pujals, A.M., Thomson, P.A., McIntosh, A M; id_orcid, M J Wright, Martin, N. G., Porteous, D.J., G Davies, Montgomery, G.W., Smith, B H, A M Fernandez-Pujals, McIntosh, A. M., A Pattie, D J MacIntyre, McIntosh, A.M., Clarke, T. K., S Padmanabhan, Medland, S. E., Pattie, A, Liewald, D C, L S Hall, Lupton, M.K., T-K Clarke, Padmanabhan, S, Martin, N G, MacIntyre, D.J., Deary, I.J.   +86 more
core   +1 more source

Polygenic prediction of the phenome, across ancestry, in emerging adulthood. [PDF]

, 2017
Identifying genetic relationships between complex traits in emerging adulthood can provide useful etiological insights into risk for psychopathology. College-age individuals are under-represented in genomic analyses thus far, and the majority of work has
Cooke, Megan, Salvatore, Jessica E, Moore, Ashlee A, Moscati, Arden, Aliev, Fazil, Savage, Jeanne E, Dick, Danielle, Edwards, Alexis C, Adkins, Daniel E, Bacanu, Silviu A, Peterson, Roseann, Webb, Bradley T, Riley, Brien P, Docherty, Anna R, Kendler, Kenneth S   +14 more
core   +1 more source

On Flexible finite polygenic models for multiple-trait evaluation [PDF]

, 2002
Finite polygenic models (FPM) might be an alternative to the infinitesimal model (TIM) for the genetic evaluation of pedigreed multiple-generation populations for multiple quantitative traits.
Bink, M.C.A.M.
core   +1 more source

Genetic testing for familial hypercholesterolemia—past, present, and future

Journal of Lipid Research, 2021
In the early 1980s, the Nobel Prize winning cellular and molecular work of Mike Brown and Joe Goldstein led to the identification of the LDL receptor gene as the first gene where mutations cause the familial hypercholesterolemia (FH) phenotype.
Marta Futema, Alison Taylor-Beadling, Maggie Williams, Steve E. Humphries   +3 more
doaj   +1 more source

The impact of known breast cancer polygenes on critical illness insurance [PDF]

, 2015
Genetic studies indicate that the inherited risk of breast cancer is mediated by the well-studied major genes BRCA1 and BRCA2, and a polygenic component, probably with many genes each making a small contribution. Recently, seven polygenes have been found
Macdonald, Angus Smith; id_orcid, Adams, Craig, Donnelly, Catherine   +2 more
core   +1 more source

Plant and pathogen genomics: essential approaches for stem rust resistance gene stacks in wheat

Frontiers in Plant Science, 2023
The deployment of disease resistance genes is currently the most economical and environmentally sustainable method of crop protection. However, disease resistance genes can rapidly break down because of constant pathogen evolution, particularly when they
Matthias Jost, Megan A. Outram, Kathy Dibley, Jianping Zhang, Ming Luo, Michael Ayliffe   +5 more
doaj   +1 more source

Are genetic risk factors for psychosis also associated with dimension-specific psychotic experiences in adolescence? [PDF]

, 2014
Psychosis has been hypothesised to be a continuously distributed quantitative phenotype and disorders such as schizophrenia and bipolar disorder represent its extreme manifestations.
Plomin, Robert, Freeman, D, Daniel Freeman, Angelica Ronald (346752), Sieradzka, D., Robert Plomin (27675), Dominika Sieradzka (549507), Cardno, Alastair G., Power Robert A., Power, Robert, Cardno, A.G., McGuire, P, McGuire, Philip, Angelica Ronald, Sieradzka Dominika, Alastair G Cardno, Ronald, Angelica, Ronald, A, Philip McGuire (325649), Robert Plomin, Sieradzka, Dominika, Freeman, Daniel, Power, RA, Power, R.A., Cardno Alastair G., Ronald Angelica, Robert A. Power (549508), Meaburn, Emma L, McGuire, P., Cardno, AG, Dudbridge Frank, Freeman Daniel, Dominika Sieradzka, Frank Dudbridge, Robert A Power, Meaburn Emma L., Meaburn, EL, Sieradzka, D, Alastair G. Cardno (549510), Plomin, R., Dudbridge, Frank, Daniel Freeman (549509), Meaburn, Emma L., Plomin Robert, Freedman, D., Power, Robert A, Plomin, R, Cardno, Alastair G, Emma L. Meaburn (397318), McGuire Philip, Philip McGuire, Dudbridge, F, Frank Dudbridge (102283), Emma L Meaburn   +53 more
core   +1 more source

Polygenic Index Inventories Documentation [PDF]

, 2021
This guide documents the key information regarding the construction and use of polygenic indexes (PGIs) for the National Longitudinal Study of Adolescent to Adult Health (Add Health) as part of the Resource Profile and User Guide of the Polygenic Index ...
Cesarini, David, Benjamin, Dan, Harris, Kathleen Mullan, Levitt, Brandt, Turley, Patrick, Okbay, Aysu   +5 more
core   +1 more source

Inheritance of Mesotrione Resistance in an Amaranthus tuberculatus (var. rudis) Population from Nebraska, USA

Frontiers in Plant Science, 2018
A population of Amaranthus tuberculatus (var. rudis) evolved resistance to 4-hydroxyphenylpyruvate dioxygenase (HPPD) inhibitor herbicides (mesotrione, tembotrione, and topramezone) in Nebraska.
Maxwel C. Oliveira, Todd A. Gaines, Amit J. Jhala, Stevan Z. Knezevic   +3 more
doaj   +1 more source