Results 111 to 120 of about 1,130,327 (225)

The Evolving Landscape of CHD Genetics: A Contemporary Guide to Genetic Testing and Management

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Congenital heart disease (CHD) is the most common birth defect, affecting an estimated 9.4/1000 infants globally. The genetics of CHD is complex, with most cases thought to have multifactorial aetiology, implicating both genetic and environmental factors.
Bridget R. O'Malley, Gary F. Sholler, Janine Smith, Gillian M. Blue   +3 more
wiley   +1 more source

Genetic Susceptibility to Periodontitis

Journal of Periodontal Research, EarlyView.
Aim: The aim of this narrative review was to identify genes carrying risk alleles associated with an increased risk of periodontitis and to place them in a biological context. Methods: The literature was reviewed based on predefined criteria. Results: The identified genes largely fall into functions linking immune response with tissue repair. The genes
Gesa M. Richter, Arne S. Schaefer
wiley   +1 more source

Established and Emerging Biomarkers to Characterize Persons at Risk for Obesity—Paving the Way for Targeted Clinical Intervention Trials—A Comprehensive Position Paper

Obesity Reviews, EarlyView.
ABSTRACT Despite all efforts, obesity remains a major health concern worldwide, with continuously increasing rates, affecting approx. 14% of the total world population, being as high as 43% in some countries. As obesity is related to numerous comorbidities, including type 2 diabetes, cardiovascular diseases, and some types of cancer, the consequences ...
Farhad Vahid, Victoria Stopa, Laurent Malisoux, Yvan Devaux, Elsa Lamy, Fernando Capela e Silva, Sarah Forberger, Tiziana de Magistris, Antoni Sureda, Margalida Monserrat‐Mesquida, Maria Pérez‐Jiménez, Rajini Nagrani, Maria Giovanna Onorati, Michele Filippo Fontefrancesco, Jonathan Turner, Mahesh S. Desai, Josep Tur, Cristina Bouzas, Gino Gabriel Bonetti, Oliver Riedel, Gitte Ravn‐Haren, Rikke Andersen, Torsten Bohn   +22 more
wiley   +1 more source

Ethical Issues Raised by Interventions to Prevent or Treat Childhood Obesity: A Systematic Qualitative Review

Obesity Reviews, EarlyView.
ABSTRACT Background Efforts to control the global obesity epidemic are increasingly focusing on preventing childhood obesity. A wide range of interventions has been implemented; however, such interventions raise important ethical issues. Aim This study aims to determine systematically the spectrum of ethical issues that are raised by interventions to ...
Marthe Smedinga, Michael Rossiter, Joshua R. Marx, Stuart McLennan   +3 more
wiley   +1 more source

Monogenic Diabetes [PDF]

The Journal of Clinical Endocrinology & Metabolism, 2010
Silvio Inzucchi, Abbas Kitabchi, Julio Rosenstock   +2 more
openaire   +1 more source

Global perspectives on monogenic forms of diabetes

Diabetologia
Abstract Monogenic forms of diabetes represent an uncommon but very heterogeneous subset of the disease, with variable associated clinical features and key differences in treatment options. In this review, we discuss how advances in precision medicine and genomic sequencing have enhanced our understanding of the aetiology and clinical ...
James Russ-Silsby, Milena Teles, Samar S. Hassan, Nancy S. Elbarbary, Cấn Thị Bích Ngọc, Elisa De Franco   +5 more
openaire   +2 more sources

Rethinking Global Obesity Guidelines: Integrating Evidence, Equity and Precision (2014–2026)

Obesity Reviews, EarlyView.
Challenges and evidence in obesity guidelines. ABSTRACT Obesity remains a global health crisis characterized by substantial heterogeneity in diagnosis, management, and policy implementation. Although numerous national and international clinical practice guidelines have been published over the past decade, their translation into evidence‐based and ...
Rosero‐Revelo Ricardo, Tamayo Mateo, Henao Diana, Juan P. Polanco, Cortés David, Juan C. Alba, Giha Valeria, Camargo Camilo, Hernández Eder, Correa Ricardo, Nassar Ricardo, Cabandugama Peminda, Marcio L. Griebeler, Burguera Bartolome   +13 more
wiley   +1 more source

The prevalence of monogenic diabetes in Australia: the Fremantle Diabetes Study Phase II.

, 2017
To determine the prevalence of monogenic diabetes in an Australian ...
Hattersley, Andrew T., Colclough, Kevin, Davis, W. A., Makepeace, A. E., Davis, T. M., Peters, K., Ellard, Sian   +6 more
core   +1 more source

Toward “Obesityomics”: Domain‐Specific Omics in Precision Obesity Medicine with a Brief AI Perspective

Obesity Reviews, EarlyView.
ABSTRACT Background Obesity's global rise has outpaced the effectiveness of “one‐size‐fits‐all” prevention and treatment strategies. The promise of precision medicine lies in addressing the etiological and biological diversity of obesity and transforming it into actionable endotypes.
Nadia Abu Samra, Sara G. I. Suliman, Mohammed Al‐Hadad, Dorret I. Boomsma, Fadwa Alhantoobi, Maithah Alsamahi, Haneen Abufarajallah, Alia Al Tikriti, Zeyar Aung, Selena Richards, Abdulrahim Sajini, Mira Mousa, Fatima Sulaiman, Wael Osman   +13 more
wiley   +1 more source

Monogenic Diabetes — A Case Series

Indian Pediatrics, 2021
Sridevi A, Naaraayan, Raghavan V, Dhakshayani, Rema, Chandramohan   +2 more
openaire   +2 more sources